Analysis of COVID-19 Incidence and Severity Among Adults Vaccinated With 2-Dose mRNA COVID-19 or Inactivated SARS-CoV-2 Vaccines With and Without Boosters in SingaporeArticle Published on 2022-08-012022-11-16 Journal: JAMA Network Open [Category] SARS, 변종, [키워드] 95% CI adjusted Against age Assessing BBIBP-CorV BNT162b2 booster cohort study Combination combinations CoronaVac COVID-19 COVID-19 vaccination death defined determine dose Effectiveness eligible Estimated greater homologous inactivated individual Infection intensive care Moderna mRNA mRNA COVID-19 vaccine mRNA vaccine mRNA-1273 no significant difference Older omicron outcome Pfizer-BioNTech provided reduction Reinfection SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 vaccination SARS-CoV-2 vaccine SARS-CoV-2 variant severe COVID-19 severe disease Sex Singapore Sinopharm Sinovac supplemental oxygen time interval vaccination Vaccine vaccine dose waned was determined were excluded women [DOI] 10.1001/jamanetworkopen.2022.28900 PMC 바로가기
Durability of Heterologous and Homologous COVID-19 Vaccine Boosts이종 및 동종 COVID-19 백신의 내구성 향상Article Published on 2022-08-012022-09-11 Journal: JAMA Network Open [Category] SARS, 변종, 진단, [키워드] Ad26 Ad26.COV2.S Adenovirus age Analysis Antibody Response Antibody responses Asian assays binding black BNT162b2 BNT162b2 vaccine boost Boston CD4+ T-cell CD8+ Cellular immune response cellular immune responses cohort study COVID-19 COVID-19 vaccine cytokine Data analysis declined elicited evaluate evaluated female Follow-up functional antibody response Heterologous heterologous prime-boost Hispanic homologous humoral humoral immune responses immune response immune responses immunization immunogenicity individual intracellular cytokine staining involved IQR Latino Massachusetts median Messenger RNA mRNA mRNA vaccine Neutralizing neutralizing antibodies titer neutralizing antibody occurred of BNT162b2 omicron outcome participant peaked potential benefit potential benefits prime-boost regimen rapid increase regimen repeated response SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants T-cell responses These data Vaccine was performed were assessed white [DOI] 10.1001/jamanetworkopen.2022.26335 PMC 바로가기 [Article Type] Article
Long-Term Outcomes after Vaccine-Induced Thrombotic Thrombocytopenia백신 유도성 혈전성 혈소판 감소증 후 장기 결과Article Published on 2022-08-012022-09-11 Journal: Viruses [Category] SARS, 진단, 치료기술, [키워드] acute phase Adenovirus adenovirus-based affected antibody Anticoagulants anticoagulation appear Arterial thrombosis AZD1222 bleeding cerebral venous sinus thrombosis ChAdOx1 ChAdOx1 nCoV-19 Cohort Cohort studies cohort study Complication coronavirus Corticosteroids COVID-19 D-dimer detectable diagnosed Diagnosis died dimer Direct discharge discharged eculizumab effective elevated enrolled Follow-up hospital hospital discharge Immunoglobulin in some Intravenous immunoglobulin IVIG limit management nCoV neurological nine observation occurred one patient oral anticoagulant outcome Patient patients PF4 Platelet platelet activation positive prothrombotic condition remained respiratory respiratory syndrome coronavirus respiratory syndrome coronavirus 2 Safe SARS-CoV-2 serious complication Seven severe respiratory syndrome single-center Sinus thrombosis survived Symptom symptom onset syndrome the disease thrombocytopenia thromboembolic Thromboembolic event Thromboembolic events thrombosis thrombotic Thrombotic thrombocytopenia Treatment two patients vaccination Vaccine venous venous sinus were given [DOI] 10.3390/v14081702 PMC 바로가기 [Article Type] Article
Examination of SARS-CoV-2 In-Class Transmission at a Large Urban University With Public Health Mandates Using Epidemiological and Genomic Methodology역학 및 게놈 방법론을 사용하여 공중 보건 위임을 받은 대도시 대학에서 SARS-CoV-2 클래스 내 전파 검사Article Published on 2022-08-012022-09-11 Journal: JAMA Network Open [Category] Coronavirus, SARS, 유전자 메커니즘, 치료기술, [키워드] activities activity analyzed average Campus causative agent Chain Reaction class cohort study conducted Contact tracing COVID-19 detectable disease transmission driving Eligible participants event Evidence examination examined faculty Genetic individual Infection instance involved outcome participant Participation physical distancing polymerase chain polymerase chain reaction Polymerase chain reaction testing Positive test Public public health ranged risk robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 transmission Sequencing suggested surveillance testing Transmission transmission of SARS-CoV-2 universities university urban vaccination variety whole genome Whole genome sequencing [DOI] 10.1001/jamanetworkopen.2022.25430 PMC 바로가기 [Article Type] Article
Comparison of Severe Maternal Morbidities Associated With Delivery During Periods of Circulation of Specific SARS-CoV-2 Variants특정 SARS-CoV-2 변이체의 순환 기간 동안 분만과 관련된 심각한 산모 이환율의 비교Multicenter Study Published on 2022-08-012022-09-11 Journal: JAMA Network Open [Category] SARS, 변종, [키워드] age Alpha Alpha variant amplification analyzed association B.1.1.7 B.1.617.2 cause center characterized clinical variable cohort study complications Control COVID-19 defined delivery Delta delta variant demographic and clinical variables disease control dominant evaluate event events Evidence evidence of example health system highest Hospitalization individual Infection IQR Maternal median morbidity multicenter nucleic acid nucleic acid amplification test Odds ratio omicron outcome outcomes over pandemic Patient patients with SARS-CoV-2 Period predominant pregnant patient pregnant patients prevention preventive measures Primary outcome reflected Respiratory complications retrospective cohort study risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleic acid secondary Secondary outcomes severity of COVID-19 significantly higher Specific Strains test result the SARS-CoV-2 type strain Variation viral strain viral strains was increased while wild-type strain [DOI] 10.1001/jamanetworkopen.2022.26436 PMC 바로가기 [Article Type] Multicenter Study
Predictive performance and clinical application of COV50, a urinary proteomic biomarker in early COVID-19 infection: a prospective multicentre cohort studyResearch article Published on 2022-08-012022-10-05 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 진단, [키워드] 95% CI Accuracy adjusted age Analysis AUC baseline Biomarker BMI capillary electrophoresis Care characteristic cohort study Comorbidities country COVID-19 dataset death died Disease progression eight Euro European country finding France funding Germany Greece high risk hospital hospitalisation Infection interim analysis less Logistic regression marker Markov chain Mild-to-moderate Ministry of Health Mortality multicentre North Odds ratio outcomes participant Participants PCR-confirmed PCR-confirmed COVID-19 peptide pilot study Poland predicted Predictive Probability progression proteomic recruited reducing reduction resulting risk SARS-CoV-2 SARS-CoV-2 pandemic Sex Spain threshold Treatment was used WHO [DOI] 10.1016/S2589-7500(22)00150-9 [Article Type] Research article
Association of Receiving a Fourth Dose of the BNT162b Vaccine With SARS-CoV-2 Infection Among Health Care Workers in Israel이스라엘 의료 종사자들 사이에서 SARS-CoV-2 감염 BNT162b 백신 4차 접종 협회Multicenter Study Published on 2022-08-012022-09-11 Journal: JAMA Network Open [Category] SARS, 변종, [키워드] 95% CI adjusted hazard ratio age Analysis benefit BNT162b BNT162b2 BNT162b2 vaccine both groups Breakthrough infection Chain Reaction cohort study COVID-19 COVID-19 infection COVID-19 infections Cox proportional hazard Critical death dose evaluate female hazard ratio HCW HCWs Health care Health care worker health care workers hospital Hospital staff infection rate medical staff Ministry of Health mitigate multicenter cohort study occurred omicron Omicron variant outcome polymerase chain polymerase chain reaction Polymerase chain reaction test positive receiving recipient reduced reduction Regression model Relative risk risk SARS-CoV-2 severe disease Symptom test result tested vaccination vaccination rate Vaccine vaccine dose variant was performed worker [DOI] 10.1001/jamanetworkopen.2022.24657 PMC 바로가기 [Article Type] Multicenter Study
Duration of Symptoms and Association With Positive Home Rapid Antigen Test Results After Infection With SARS-CoV-2SARS-CoV-2 감염 후 증상 기간 및 양성 가정 신속 항원 검사 결과와의 연관성Article Published on 2022-08-012022-09-12 Journal: JAMA Network Open [Category] SARS, 진단, [키워드] Antigen association cohort study Duration duration of symptom home positive Rapid Result SARS-CoV-2 SARS-COV-2 infection Test [DOI] 10.1001/jamanetworkopen.2022.25331 PMC 바로가기 [Article Type] Article
Comparison of Laboratory and Hemodynamic Time Series Data Across Original, Alpha, and Delta Variants in Patients With Multisystem Inflammatory Syndrome in ChildrenArticle Published on 2022-08-012022-11-16 Journal: Pediatric critical care medicine : a journal of th [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome all subject Alpha variant assist children Cohort cohort study Continuous coronavirus Delta delta variant entire cohort evaluated extracorporeal membrane oxygenation had more hemodynamic hospital Hospitalization ICU Infection Inflammatory INR Laboratory laboratory parameter Laboratory results LOS male measurement mechanical ventilation median age median value medication MIS-C Modification Mortality occurred original outcome parameter Patient Potassium Prothrombin time Sery severity sodium Symptom syndrome Tachycardia time Treatment protocol variant variants variants of concern ventricular WBCs [DOI] 10.1097/PCC.0000000000002976 PMC 바로가기
Quality of life, respiratory symptoms, and health care utilization 1 year following outpatient management of COVID-19: a prospective cohort study Research Published on 2022-07-292022-10-05 Journal: Scientific Reports [Category] 임상, 치료법, [키워드] 95%CI adjusted assessment Care characterized cohort study COVID-19 determine employment EQ-5D Exercise limitation female Follow-up Health Impact IMPROVE independent Infection IQR likelihood Linear regression management median mild infection pathophysiology persistent primary care prospective cohort study Quality Quality of life reported Research respiratory symptom respiratory symptoms risk risk factor scored Sex significantly subject Symptom [DOI] 10.1038/s41598-022-17243-7 [Article Type] Research