Critical – Page 15 – Communicable Diseases Research

Performance evaluation of the Roche Elecsys® Anti-SARS-CoV-2 immunoassays by comparison with neutralizing antibodies and clinical assessment

Article

Published on 2022-09-152022-11-15
Journal: PLoS ONE [Category] SARS, 진단, 치료기술, 치료제,

MiRNA-SARS-CoV-2 dialogue and prospective anti-COVID-19 therapies

MiRNA-SARS-CoV-2 대화 및 전향적인 항-COVID-19 치료법

Review

Published on 2022-09-152022-09-11
Journal: Life sciences [Category] COVID19(2023년), MERS, SARS, 바이오마커, 변종, 비임상, 진단, 치료기술, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 adverse effect adverse effects Affect antiviral response approach approved Biomarker caused Cell signaling chance Clinical significance Comorbidities coronavirus Coronavirus-2 country COVID-19 COVID-19 illness COVID-19 infection COVID-19 pathogenesis COVID-19 patient Critical death detect differential expression disease disease onset disease pathology effort etiology expression FDA focus Host host cell host inflammatory response host miRNA host miRNAs identify Infection life cycle microRNA miRNA miRNAs molecular interaction non-coding RNA offer pathogen Pathogen-host interaction patients with COVID-19 post-transcriptionally quest reduce respiratory respond RNA RNA silencing SARS Coronavirus SARS coronavirus 2 SARS coronavirus 2. SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 virus Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severity Signaling target gene the SARS-CoV-2 virus therapy treat Treatment Viral viral miRNA viral miRNAs
[DOI] 10.1016/j.lfs.2022.120761 PMC 바로가기 [Article Type] Review

Robust and efficient COVID-19 detection techniques: A machine learning approach

Article

Published on 2022-09-152022-11-15
Journal: PLoS ONE [Category] SARS, 치료기술, 치료제,

SARS-CoV-2 Omicron sublineages exhibit distinct antibody escape patterns

Article

Published on 2022-09-142022-10-06
Journal: Cell Host & Microbe [Category] COVID19(2023년), SARS, 변종, 진단,

Circulating pyruvate is a potent prognostic marker for critical COVID-19 outcomes

Article

Published on 2022-09-142022-11-15
Journal: Frontiers in Immunology [Category] SARS, 바이오마커,

[키워드] abundance acute phase acute respiratory syndrome Alter Analysis approach assays body mass index C-reactive protein circulating clinical decision Compromised coronavirus COVID-19 COVID-19 pathogenesis COVID-19 patient creatinine criterion Critical Critically ill cut-off value determine disease disrupt driven by dysregulation energy-related metabolites evaluated Extracellular fluorometric quantification Glucose Health Host Host immune response immune response implicated IMPROVE Increased independent predictor Infection Lactate mechanisms metabolism metabolite metabolomics mitochondrial outcome outcomes Patient Potential biomarker Prognosis Prognostic marker provided pyruvate quantification Quantitative recruited risk SARS-CoV-2 SARS-COV-2 infection semi-targeted metebolomics. serum severe COVID-19 illness severity Signaling Stratification Support validation cohort virus
[DOI] 10.3389/fimmu.2022.912579 PMC 바로가기

SARS-CoV-2 Infection and Pregnancy: Maternal and Neonatal Outcomes and Placental Pathology Correlations

Article

Published on 2022-09-142022-11-15
Journal: Viruses [Category] SARS, 진단, 치료기술,

[키워드] accumulating amniotic Analysis anti-SARS-CoV-2 Autopsy available data Blood Care clinical Clinical characteristics Clinical management correlation Course COVID-19 Critical demise elevated Evidence fetal Hospital stay IgM antibody levels IHC immunoexpression immunohistochemistry implication Infant Infants Infection initial Laboratory results Maternal maternal and neonatal outcome Nasopharyngeal swab Neonatal outcome pathological finding pathology patients Placenta placental Placental infection placental pathology positive Positive test Pregnancy pregnant women risk RT-PCR RT-PCR testing SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 genome SARS-CoV-2-positive patients SARS-CoV-2-specific IgG selected serum significantly study group Surveillance Transmission umbilical cord blood vertical transmission was performed women
[DOI] 10.3390/v14092043 PMC 바로가기

Photochemical Identification of Auxiliary Severe Acute Respiratory Syndrome Coronavirus 2 Host Entry Factors Using μMap

Article

Published on 2022-09-142022-11-16
Journal: Journal of the American Chemical Society [Category] SARS, 변종,

Targeting Doublecortin-Like Kinase 1 (DCLK1)-Regulated SARS-CoV-2 Pathogenesis in COVID-19

Article

Published on 2022-09-142022-11-15
Journal: Journal of Virology [Category] SARS, 치료기술, 치료제,

[키워드] Activation amplified amplify analyzed blocked Blood Cell chemokine chronic liver disease Chronic Liver Diseases circulating comorbid disease Comorbidity contribute controls correlated COVID-19 COVID-19 patients Critical cytokine cytokine secretion DCLK1 DDCLK1 decrease disease severity dysregulation expression Factor Factors Gain growth factor hospitalized patient Host Hyperinflammatory response immune Immune cell immune response immunosuppressive in viral in vitro infected cells Inflammation Inflammatory cytokine inflammatory pathway inhibition inhibitor Innate immunity involved kinase Live virus liver livers loss of function lung Lung disease Macrophage mononuclear cell mononuclear cells Mortality neutrophil normalized Pathogenesis pathology Patient Peripheral blood potential therapeutic target Prevalence pro-inflammatory profile proinflammatory promoted promoter Protein S100A9 SARS-CoV-2 SARS-CoV-2-infected cell secretion severity of COVID-19 Signaling subject targeting Treatment Viremia virus production virus replication with COVID-19 β-catenin
[DOI] 10.1128/jvi.00967-22 PMC 바로가기

Enhancing the Immunogenicity of RBD Protein Variants through Amino Acid E484 Mutation in SARS-CoV-2

Article

Published on 2022-09-132022-11-15
Journal: Viruses [Category] SARS, 변종, 진단, 치료기술,

Contribution of Coronavirus-Specific Immunoglobulin G Responses to Complement Overactivation in Patients with Severe Coronavirus Disease 2019

Article

Published on 2022-09-132022-11-15
Journal: The Journal of Infectious Diseases [Category] SARS, 진단,

[키워드] Activation acute respiratory syndrome addition Analysis and antibodies antibody C1q circulating classical classical pathway common cold common cold coronavirus common cold Coronaviruses complement complement system coronavirus coronavirus disease correlated COVID-19 Critical demonstrated develop disease disease severity greater healthy control hospitalized patient IgG response immune complex Immunoglobulin Immunoglobulin G implicated mechanism moderate modify outcome overactivation Pathogenesis Patient patients with COVID-19 plasma response responsible RNA SARS-CoV-2 severe COVID-19 severe patients severity systemically therapeutic strategy with COVID-19
[DOI] 10.1093/infdis/jiac091 PMC 바로가기