Comparison of Antibody Class-Specific SARS-CoV-2 Serologies for the Diagnosis of Acute COVID-19급성 COVID-19 진단을 위한 항체 종류별 SARS-CoV-2 혈청학 비교Article Published on 2021-03-192022-09-12 Journal: Journal of Clinical Microbiology [Category] SARS, 진단, [키워드] acute respiratory syndrome Analysis analyzed antibodies AUC benefit Clinical severity complementary confidence interval coronavirus coronavirus disease COVID-19 Critical Cutoff Diagnosis diagnostic diagnostic value disease evaluated Evidence examined false-positive result hospitalized patient hospitalized patients IgA IgG IgG and IgM IgM IgM antibody immunodiagnostics Immunoglobulin Infection intubation limitation management optical Patient PCR PCR testing PCR-negative RBD Receptor binding domain SARS-CoV-2 SARS-COV-2 infection sensitivity Sensitivity and specificity Seroconversion serological test serology serology testing serology tests spike Suspected symptom onset utility [DOI] 10.1128/JCM.02026-20 PMC 바로가기 [Article Type] Article
Validation of an admission coagulation panel for risk stratification of COVID-19 patientsCOVID-19 환자의 위험 계층화를 위한 입원 응고 패널의 검증Research Article Published on 2021-03-192022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료기술, [키워드] 95% CI abnormality Activation Admission African American age Atlanta clinical clinical outcomes Coagulation coagulation panel Cohort complex complications coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Cutoff D-dimer Deep vein Deep vein thrombosis dimer effective Endpoint female FIBRIN hospital ICU admission identify intubation Ischemic Stroke marker monomer Mortality Myocardial infarction Negative predictive value Observational cohort study outcome parameter Patient plasma Predictive value Pulmonary embolism risk risk stratification sensitivity stroke thrombin thrombosis thrombotic thrombotic complication Thrombotic complications thrombotic event Thrombotic events validation [DOI] 10.1371/journal.pone.0248230 PMC 바로가기 [Article Type] Research Article
Serum ferritin levels in inflammation: a retrospective comparative analysis between COVID-19 and emergency surgical non-COVID-19 patients염증에서의 혈청 페리틴 수치: COVID-19와 응급 수술 비-COVID-19 환자 간의 후향적 비교 분석Observational Study Published on 2021-03-082022-09-01 Journal: World Journal of Emergency Surgery : WJES [Category] 바이오마커, 임상, 진단, [키워드] Acute inflammation affected Analysis appear change COVID Covid negative patients COVID-19 Cutoff Cytokine storm defined disease ferritin ferritin level group hepcidin implicated Infection Inflammation inflammatory process Inflammatory response interquartile range involved IQR iron Iron metabolism leucocytosis Leukocytosis Mann-Whitney test marker mechanism median metabolism Modification negative patients non-COVID-19 patient pathogenic Patient phlogistic Prognostic factor Prognostic factors progression Result retrospective Retrospective analysis SARS-CoV-2 SARS-COV-2 infection Sepsi Serum ferritin significantly higher Spread surgery surgical Swab the median total blood Transferrin two-tailed [DOI] 10.1186/s13017-021-00354-3 PMC 바로가기 [Article Type] Observational Study
Diagnostic accuracy of subjective dyspnoea in detecting hypoxaemia among outpatients with COVID-19: a retrospective cohort studyCOVID-19 외래 환자의 저산소혈증 감지에서 주관적 호흡곤란의 진단 정확도: 후향적 코호트 연구Article Published on 2021-03-082022-09-11 Journal: BMJ Open [Category] SARS, 치료기술, [키워드] 95% CI Accuracy Canada Care COVID-19 COVID-19 patients criteria cut-off Cutoff defined diagnosed diagnosing diagnostic Diagnostic accuracy diagnostic tests Dyspnoea evaluated high-risk patient High-risk patients hospital hypoxaemia Infectious diseases likelihood ratio majority management measure Medical Research Council Mild-to-moderate NPV Outpatient oxygen oxygen saturation Oxygenation Patient patients with COVID-19 PPV Predictive Predictive value primary analysis public health retrospective cohort study sensitivity specificity study period Subjective to define Toronto treated Virtual care was used with COVID-19 [DOI] 10.1136/bmjopen-2020-046282 PMC 바로가기 [Article Type] Article
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials단회 투여 및 ChAdOx1 nCoV-19(AZD1222) 백신의 면역원성 및 효능에 대한 추가 투여 시간의 영향: 4건의 무작위 시험에 대한 통합 분석Meta-Analysis Published on 2021-03-062022-09-10 Journal: Lancet (London, England) [Category] MERS, SARS, 임상, [키워드] 1:1 95% CI addition administration Ageusia All participants Analysis Anosmia antibody antibody levels Antibody Response Antibody responses approved assigned AstraZeneca AZD1222 baseline binding antibody booster dose booster doses Brazil category ChAdOx1 ChAdOx1 nCoV-19 Clinical research Coalition control group control vaccine cough COV005 COVID-19 COVID-19 disease COVID-19-related death Cutoff death defined described dose doses double-blind Efficacy Emergency use Endpoint Evidence evidence of exclusion exploratory Exploratory analyses Exploratory analysis Fever finding first dose FIVE Follow-up for inclusion foundation funding geometric mean geometric mean ratio GMR had no Hospital admission immunoassay immunogenicity immunogenicity data independent indicated individual Infection initial Innovation interim analysis ISRCTN89951424 less lower dose Medicine Medicines Medicines and Healthcare products Regulatory Agency Melinda Gate Melinda Gates N protein NAAT NAAT-positive swab network neutralisation NIHR no evidence of nucleic acid nucleic acid amplification nucleic acid amplification test observation offered Older outcomes Oxford pandemic participant phase 2/3 phase 3 study positive swab primary analysis primary endpoint Primary outcome prime-boost interval priming PROTECT pseudovirus randomised controlled Randomised trial Randomly receive receiving recruited regimen Registered regulatory authority response Safety saline placebo SARS-COV-2 infection SARS-CoV-2 N protein second dose secondary Serious Adverse Events seronegative Seven Shortness of breath single-blind Single-dose South South Africa Standard dose subset supported Swab swabs Symptom symptomatic COVID-19 disease symptomatic infection Telle the primary endpoint the timing the vaccine Trial vaccination Vaccine vaccine efficacy Valley Viral Viral particles [DOI] 10.1016/S0140-6736(21)00432-3 PMC 바로가기 [Article Type] Meta-Analysis
Prognostic Values of Serum Ferritin and D-Dimer Trajectory in Patients with COVID-19COVID-19 환자에서 혈청 페리틴 및 D-이량체 궤적의 예후 값Article Published on 2021-03-052022-09-10 Journal: Viruses [Category] SARS, 바이오마커, [키워드] acute lung injury AUC Care Cerner Clinical outcome clinical outcomes Cohort Course COVID-19 COVID-19 infected patient COVID-19 pandemic COVID-19 patient COVID-19 patients Cutoff cytokine Cytokine storm Cytokine storm syndrome Cytokines D-dimer determine dimer disease course Elevation females ferritin Health Hospitalization house in-hospital mortality invasive Laboratory Laboratory results logistic-regression models Longitudinal data Lung injury male Mortality multiorgan failure optimal prognostic cutoffs patients patients with COVID-19 predict pro-inflammatory cytokine pro-inflammatory cytokines professional prognostic Prognostic value repeated Research resource resulting retrospective serum Serum ferritin syndrome the disease trajectory value ventilator were used with COVID-19 [DOI] 10.3390/v13030419 PMC 바로가기 [Article Type] Article
Investigating the effect of national government physical distancing measures on depression and anxiety during the COVID-19 pandemic through meta-analysis and meta-regressionReview Article Published on 2021-03-022022-10-29 Journal: Psychological Medicine [Category] COVID-19, MERS, SARS, [키워드] Anxiety Asia burden China CINAHL citation conducted content COVID-19 COVID-19 pandemic current Cutoff database Depression disorders eligibility criteria Epidemic Europe GAD-7 Government Health healthcare providers impacted implementation implication index individual Intervention likelihood limitation Local lowest measure Mental Disorders mental health mental health services Meta-analysis meta-regression National objective original outcomes Oxford participant patients PHQ-9 physical distancing measure physical distancing measures positive Prevalence PsycINFO public transport Region reported response Result social isolation Support Web of Science were assessed [DOI] 10.1017/S0033291721000933 PMC 바로가기 [Article Type] Review Article
The difference between IgM and IgG antibody prevalence in different serological assays for COVID-19; lessons from the examination of healthcare workersCOVID-19에 대한 다양한 혈청학적 분석에서 IgM과 IgG 항체 유병률의 차이; 의료 종사자 시험의 교훈Article Published on 2021-03-012022-09-12 Journal: International immunopharmacology [Category] MERS, SARS, 진단, [키워드] Accuracy analyzed antibody Antibody prevalence Antibody testing Characteristics chemiluminescence immunoassay CLIA Community COVID-19 Cutoff determine evaluate healthcare worker higher risk IgG IgG and IgM IgM IgM and IgG immunochromatography Infection participant performed positive Prevalence promote proportion quantitative antibody test rapid test kit required Research Serological assay serology assay [DOI] 10.1016/j.intimp.2020.107360 PMC 바로가기 [Article Type] Article
Estimating the cumulative incidence of SARS-CoV-2 with imperfect serological tests: Exploiting cutoff-free approaches불완전한 혈청 검사로 SARS-CoV-2의 누적 발생률 추정: 차단 없는 접근 방식 활용Research Article Published on 2021-02-262022-09-12 Journal: PLoS Computational Biology [Category] MERS, 진단, [키워드] Accuracy antibody Antibody Response Antibody responses approach Asymptomatic asymptomatic infection Blood can be used circumvent confirmed case confirmed cases controls cumulative cumulative incidence Cutoff determine distribution elicit error estimate estimation False negative false negative results False positive fraction Guidance identify incidence individual individuals Infection leads less marker measure Measures Mild mixture model outperform pandemic parameter pathogen Pathogens Population Prevalence provided quantitative test required SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 pandemic SARS-CoV-2 specific antibodies SARS-CoV-2 specific antibody Sensitivity and specificity sera serological serological test Serological testing Serological tests seropositive seropositive individual seropositive individuals Serosurvey Serosurveys serum specific antibodies specific type specific types statistical statistical inference the SARS-CoV-2 to define yielding [DOI] 10.1371/journal.pcbi.1008728 PMC 바로가기 [Article Type] Research Article
Estimating COVID-19 Pneumonia Extent and Severity From Chest Computed TomographyPhysiology Published on 2021-02-152022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] 95%CI adjusted Admission age association AUC average Computed tomography Concentration controls correlated COVID-19 COVID-19 patient CRP CT-estimated lung volume CT-estimated lung weight Cutoff deep learning defined differential diagnosis evaluate examined expressed extension healthy subject ICU lung Mild moderate Mortality outcomes Patient Pneumonia predicted Predictive R 2 radiological Result ROC analysis severe pneumonia severity severity of COVID-19 Sex significantly higher Stratification variables ventilatory support Volume was used were assessed Z-score [DOI] 10.3389/fphys.2021.617657 PMC 바로가기 [Article Type] Physiology