Antigen production and development of an indirect ELISA based on the nucleocapsid protein to detect human SARS-CoV-2 seroconversion인간 SARS-CoV-2 혈청전환을 검출하기 위한 뉴클레오캡시드 단백질에 기초한 간접 ELISA의 항원 생산 및 개발Article Published on 2021-12-012022-09-11 Journal: Brazilian journal of microbiology : [publication o [Category] MERS, 진단, 치료법, [키워드] Accuracy controls COVID-19 COVID-19 case COVID-19 cases described detect determine develop ELISA ELISA kit enzyme-linked immunosorbent enzyme-linked immunosorbent assay Escherichia coli exposure to expressed head Head-to-head comparison helping homogeneity human SARS-CoV-2 humoral Humoral response identify immunization Immunological test mass production nucleocapsid protein Protein purified qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 nucleocapsid sensitivity Sensitivity and specificity sera Seroconversion serological assays the SARS-CoV-2 Vaccines was used [DOI] 10.1007/s42770-021-00556-6 PMC 바로가기 [Article Type] Article
Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsuleLianhuaqingwen Capsule을 투여 한 후 글리 시르 시리 사르 우랄 렌 시스 뿌리 (Gancao)에서 유래 한 슈도 알로 스테 겐 화합물의 약동학 적 식별Clinical Trial Published on 2021-12-012022-08-31 Journal: Acta pharmacologica Sinica [Category] 바이오마커, 임상, 치료제, [키워드] 11β-hydroxysteroid dehydrogenase 2 24-hydroxyglycyrrhetic acid access acid activated bile characterized China circulating metabolite colonic colonic microbiota Combination component components Compound condition COVID-19 COVID-19 treatment dehydrogenase exposure to facilitate feces Gancao-induced pseudoaldosteronism glycyrrhetic acid Glycyrrhiza uralensis glycyrrhizin hepatic human kidney Human plasma implication in vitro induce inhibit inhibiting intestinal intestinal absorption LianhuaQingwen licorice licorice-induced pseudoaldosteronism. liquiritigenin liver membrane permeability metabolism metabolite microbiota pharmacokinetic plasma protein Plasma Protein Binding Protein binding receiving renal Safe Saponin significant level systemic Therapeutic benefit Transport Treatment treatment for COVID-19 tubular reabsorption Volunteer volunteers [DOI] 10.1038/s41401-021-00651-2 PMC 바로가기 [Article Type] Clinical Trial
DrugWAS: Drug-wide Association Studies for COVID-19 Drug RepurposingDrugWAS: COVID-19 약물 용도 변경에 대한 약물 전반의 협회 연구Article Published on 2021-12-012022-09-11 Journal: Clinical Pharmacology and Therapeutics [Category] MERS, 신약개발, [키워드] 95% CI 95% confidence interval Admission Analysis applied association azelastine center clinical trials cohort study coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 diagnosis COVID-19 disease COVID-19 severity death Dextromethorphan diphtheria toxoid drug drugs Efficacy EHR EHR data Electronic health record estradiol ethinyl estradiol exposure to fatty acids Flaxseed fluticasone Health health record ibuprofen identify IMPROVE intensive care intensive care unit list lower risk mechanical ventilation multivariable logistic regression Odds ratio omega-3 Omega-3 fatty acids outcomes overlap pandemic patients with COVID-19 performed pertussis vaccine pneumococcal polysaccharide vaccine Potential treatment Primary outcome Propensity score pseudoephedrine randomized clinical trial repurposing retrospective cohort risk of death secondary Secondary analyses Secondary outcomes significantly tetanus toxoid ubidecarenone university Vaccine Vaccines was selected Weighting [DOI] 10.1002/cpt.2376 PMC 바로가기 [Article Type] Article
Automatic detection of COVID-19 vaccine misinformation with graph link prediction그래프 링크 예측으로 코로나19 백신 잘못된 정보 자동 감지Article Published on 2021-12-012022-09-11 Journal: Journal of biomedical informatics [Category] SARS, 치료기술, 치료제, [키워드] addition Automatic automatic detection automatically COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines dataset detect Efficacy experimental results exposure to function Hesitancy highest Intervention knowledge Knowledge graph knowledge graph embedding language machine machine learning media misinformation natural natural language natural language processing platform provided social media Spread target the vaccine Vaccine Vaccine hesitancy vaccine misinformation. Vaccines Volume [DOI] 10.1016/j.jbi.2021.103955 PMC 바로가기 [Article Type] Article
Factors Associated with Mental Health Outcomes: Results from a Tertiary Referral Hospital in Lebanon during the COVID-19 Pandemic정신 건강 결과와 관련된 요인: COVID-19 팬데믹 기간 동안 레바논에 있는 3차 의뢰 병원의 결과Article Published on 2021-12-012022-09-11 Journal: The Libyan journal of medicine [Category] SARS, 치료기술, [키워드] altruism Anxiety association caused conducted coronavirus disease COVID-19 COVID-19 outbreak COVID-19 pandemic COVID-19 patients cross-sectional cross-sectional study death demographics Depression depressive detect dimensions exposure to Factor finding Fisher General population HCW HCWs healthcare worker Healthcare workers hospital impacts increased risk Lebanon less mental health participated positive preparedness Referral reported Result risk Risk perception risk perceptions risks. Stress suggested Tertiary the disease variables were used [DOI] 10.1080/19932820.2021.1901438 PMC 바로가기 [Article Type] Article
COVID-19 among children seeking primary paediatric care with signs of an acute infection급성 감염의 징후가 있는 1차 소아과 진료를 찾는 어린이들 사이의 COVID-19Case Reports Published on 2021-12-012022-09-11 Journal: Acta paediatrica (Oslo, Norway : 1992) [Category] SARS, 진단, 치료기술, [키워드] acute infection Care children Clinical finding Clinical findings clinics collected correlated cough COVID-19 detectable determine Evidence evidence of exposure to Factor female Fever Gastrointestinal symptom infected with SARS-CoV-2 Infection infection with SARS-CoV-2 infections Influenza median age not differ out-patient paediatrics participated positive primary care respiratory respiratory tract infection rhinitis Sample SARS-CoV-2 SARS-CoV-2 RNA seeking Seven significantly Symptom tested [DOI] 10.1111/apa.16101 PMC 바로가기 [Article Type] Case Reports
Exposure to COVID-19 during the First and the Second Wave of the Pandemic and Coronavirus-Related PTSD Risk among University Students from Six Countries—A Repeated Cross-Sectional StudyArticle Published on 2021-11-262022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] association conducted coronavirus disease country COVID-19 COVID-19 pandemic COVID-19 symptom COVID-19 symptoms cross-national cross-sectional Cutoff death Depression Diagnosis economic status evaluated exposure to Exposure to COVID-19 female gender Gender Germany Hospitalized increase in moderate pandemic participant Poland post-traumatic Prevalence PTSD quarantine repeated risk Russia second severity Slovenia Stress student students syndrome Turkey Ukraine university Wave worsened worsening [DOI] 10.3390/jcm10235564 PMC 바로가기 [Article Type] Article
COVID-19 Infection Among Women in Iran Exposed vs Unexposed to Children Who Received Attenuated Poliovirus Used in Oral Polio Vaccine경구 소아마비 백신에 사용된 약독화된 소아마비 바이러스에 감염된 어린이와 노출되지 않은 이란 여성의 COVID-19 감염Research Published on 2021-11-242022-09-12 Journal: JAMA Network Open [Category] MERS, 진단, 폴리오, [키워드] 95% CI age Analysis Care Chain Reaction children cohort study conducted COVID-19 COVID-19 infection COVID-19 vaccine develop diagnosed diagnosed with COVID-19 evaluate exclusion criteria exposure exposure to finding Follow-up group had no Health Health care Health Organization Importance incidence of COVID-19 Inclusion inclusion and exclusion criteria individual Infection Infectious disease Infectious diseases innate immune system IQR Iran less Live attenuated vaccine Live attenuated vaccines longitudinal cohort study measure median mother objective OPV oral organization participant Petroleum Point polio Polio vaccine Poliovirus Probability protective effect Received receiving Relevance Result SARS-CoV-2 setting significantly Stimulation study period study population survival curve Survival curves symptomatic symptomatic COVID-19 symptomatic infection Vaccine with COVID-19 women [DOI] 10.1001/jamanetworkopen.2021.35044 PMC 바로가기 [Article Type] Research
Seroprevalence of SARS-CoV-2 Antibodies Among Children in School and Day Care in Montreal, Canada캐나다 몬트리올의 학교 및 탁아소 어린이들 사이에서 SARS-CoV-2 항체의 혈청 유병률Research Published on 2021-11-232022-09-10 Journal: JAMA Network Open [Category] MERS, SARS, 변종, 진단, 치료기술, 치료제, [키워드] 95% CI absence adjusted age analyzed baseline Canada Chain Reaction children clinical symptom Clinical symptoms cohort study collected COVID-19 COVID-19 pandemic COVID-19 symptom Day dried blood spot Dried blood spots ELISA enrolled enzyme-linked immunosorbent enzyme-linked immunosorbent assay epicenter estimate Étude exposure exposure to female finding First wave Importance individuals information learning mass vaccination measure Mild mild symptoms minority group Montreal Montreal, Canada MOST objective open outcome parent parents participant Participants Point positive Potential primary schools provide provided question questionnaire Racial Relevance Result RT-PCR SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody School Schools secondary schools selected serological seropositive Seroprevalence setting Sociodemographic tested the mean Transmission vaccination variants of concern were infected white [DOI] 10.1001/jamanetworkopen.2021.35975 PMC 바로가기 [Article Type] Research
Seroprevalence of SARS-CoV-2 in a Large Cohort of Italian Police Officers이탈리아 경찰의 대규모 집단에서 SARS-CoV-2의 혈청 유병률Article Published on 2021-11-202022-09-12 Journal: International Journal of Environmental Research an [Category] MERS, SARS, 진단, [키워드] 95% CI Asymptomatic case baseline booster category country COVID-19 COVID-19 vaccine cross-sectional cross-sectional study dose dysgeusia dysosmia exposure to identify IgG and IgM Influenza Italian Italy MOST Neutralizing antibodies neutralizing antibody northern regions occupational exposure Officer participated police police officers positive predictor Prognostic value Region reported risk SARS-CoV-2 SARS-COV-2 infection seropositive seropositive subject seropositive subjects Seropositivity Seroprevalence Sex state subject Symptom vaccination was tested [DOI] 10.3390/ijerph182212201 PMC 바로가기 [Article Type] Article