Neutrophil-mediated oxidative stress and albumin structural damage predict COVID-19-associated mortality호중구 매개 산화 스트레스와 알부민 구조적 손상은 COVID-19 관련 사망률을 예측합니다Research Article Published on 2021-11-252022-09-12 Journal: eLife [Category] MERS, 진단, [키워드] accumulated albumin analyzed Anti-inflammatory anticoagulation antioxidant Blood blood sample candidate COVID-19 mortality COVID-19 treatment critically ill COVID-19 patients critically ill patients died Evidence faster Fatty acid functions healthy individual Human human serum albumin damage hydrogen peroxide in-hospital mortality indicated Kaplan–Meier survival analysis marker means median Mortality neutrophil Neutrophils non-survivor Non-survivors outcome oxidative stress parameter Patient plasma predict predicted Protein recruited reduced risk serum albumin severe patients significantly subject survivor the mean Transport Whole blood [DOI] 10.7554/eLife.69417 PMC 바로가기 [Article Type] Research Article
Construction and Application of an Intelligent Response System for COVID-19 Voice Consultation in China: A Retrospective StudyMedicine Published on 2021-11-232022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] accounted Algorithm Analysis analyzed application Beijing character China China Unicom clinics close contact collected construction consultation contribute COVID-19 Cross-infection develop Diagnosis Effects Efficiency error functions groups Guidance healthcare healthcare services implementation individual information inquiry intelligent response system lowest machine-learning measure medical services Mobile National Health Commission novel coronavirus disease outbreak physical proportion provided Public Quantitative Rate resources response statistical System Treatment voice voice consultation [DOI] 10.3389/fmed.2021.781781 PMC 바로가기 [Article Type] Medicine
The impact of e-learning during COVID-19 pandemic on students’ body aches in PalestineArticle Published on 2021-11-172022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, SARS, [키워드] activities body ache correlated country COVID-19 pandemic Duration Effect Epidemiology evaluate functions Google form Health occupations increase increase in Musculoskeletal Musculoskeletal pain Pain pandemic participant participated questionnaire severity subject university [DOI] 10.1038/s41598-021-01967-z PMC 바로가기 [Article Type] Article
Mobile Apps Leveraged in the COVID-19 Pandemic in East and South-East Asia: Review and Content AnalysisReview Published on 2021-11-112022-10-31 Journal: JMIR mHealth and uHealth [Category] COVID-19, MERS, SARS, [키워드] addition Analysis analyzed Apple Applications Asia Asian Characteristics China conducted content coronavirus COVID-19 COVID-19 case COVID-19 pandemic COVID-19 vaccination database Descriptive statistics determine Digital health dissemination early stage East eHealth eligible examined function functions Google Play Government Health health monitoring Health policy highlight Hong Kong Indonesia information Japan majority Malaysia management mandatory media mHealth Mobile Mobile App mobile apps Mobile health MOST objective Other pandemic population subset public health public health measure quarantine raising released resource Result review RStudio searched Singapore South Korea Support supported Taiwan telehealth Telemedicine the timing Vaccine variety website were used [DOI] 10.2196/32093 PMC 바로가기 [Article Type] Review
MEDTEC Students against Coronavirus: Investigating the Role of Hemostatic Genes in the Predisposition to COVID-19 SeverityArticle Published on 2021-11-092022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] MTHFR 95%CI acute respiratory syndrome ADAMTS13 Analysis association Association analysis Characteristics characterized clinical heterogeneity Cohort conducted Control coronavirus coronavirus disease COVID-19 COVID-19 severity database degree distribution Engineering evidenced extreme functions General population Genes Genetic Genetic predisposition Hemostasis Hemostatic hemostatic genes Host intrinsic investigated Italian Manifestations median Medicine Meta-analysis MTHFR MTR pandemic performed polygenic risk score polymorphism predicted predisposition PROC Regeneron risk role SARS-CoV-2 severe COVID-19 severe COVID-19 patient severity significantly single-nucleotide student susceptibility THBS2 the disease Thromboembolic events university variant virus with COVID-19 [DOI] 10.3390/jpm11111166 PMC 바로가기 [Article Type] Article
The Impact of the COVID-19 Pandemic on the Composition of Dietary Supplements and Functional Foods Notified in PolandArticle Published on 2021-11-092022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] changed characterized concerning COVID COVID-19 COVID-19 pandemic determine dietary dietary supplement dietary supplements Effects food functional functions Health highest Impact increase in ingredient mineral Minerals pandemic Poland Potassium promoted Psychological Registered shown significantly higher therapy Vitamin vitamins were used [DOI] 10.3390/ijerph182211751 PMC 바로가기 [Article Type] Article
Circulation and Evolution of SARS-CoV-2 in India: Let the Data Speak인도에서 SARS-COV-2의 순환 및 진화 : 데이터가 말하자Article Published on 2021-11-082022-09-10 Journal: Viruses [Category] MERS, SARS, 변종, [키워드] Analysis approaches being characteristic circulating Cluster Clustering Comparative genomics Complete confirmed case confirmed cases constellation contributed country COVID-19 COVID-19 pandemic deaths Delta Evolution of SARS-CoV-2 evolutionary dynamics function functions genetics genomes sequenced glycosylation immune evasion impacted implication India isolate lack Lineage lineage diversity Local Mutation neutralization pandemic Phylogenetic tree Phylogeny Population genetics Positive selection reported SARS-CoV-2 sequenced sequencing coverage Site spike Spike protein Spread state Substitution substitutions Surveillance tree topology union variant of concern variant of interest variants variants of concern variants of interest Variation virus bioinformatics virus–host interactions VOCs VOIs [DOI] 10.3390/v13112238 PMC 바로가기 [Article Type] Article
Beta-Glucans from Fungi: Biological and Health-Promoting Potential in the COVID-19 Pandemic EraReview Published on 2021-11-062022-10-31 Journal: Nutrients [Category] COVID-19, MERS, [키워드] β-glucans anticancer Antiviral Bacteria Bioactivity Biological biological response modifier characterized COVID-19 food functions immune immunomodulatory properties immunomodulatory property key factor macrofungi Mushrooms plants polysaccharide Potential recent receptor SARS-CoV-2 Structure Treatment Viral diseases [DOI] 10.3390/nu13113960 PMC 바로가기 [Article Type] Review
Selection for constrained peptides that bind to a single target proteinArticle Published on 2021-11-032022-10-29 Journal: Nature Communications [Category] COVID-19, MERS, SARS, [키워드] adhere Antibiotics bind binding build diagnostics E. coli enzyme Escherichia coli expression functions identify in vivo microbial Natural product synthesis pathway peptide produced Protein Receptor binding domain RNA polymerase Secondary Metabolite Selection Signaling spike Synthetic biology target protein the SARS-CoV-2 was performed [DOI] 10.1038/s41467-021-26350-4 PMC 바로가기 [Article Type] Article
New Insights Into Drug Repurposing for COVID-19 Using Deep Learning딥 러닝을 사용하여 COVID-19에 대한 약물 용도 변경에 대한 새로운 통찰력Review Published on 2021-11-012022-09-11 Journal: IEEE transactions on neural networks and learning [Category] MERS, 신약개발, 치료제, [키워드] Accessibility Accuracy Activation adopted Algorithms approach approaches black box complex complex diseases coronavirus disease Coronavirus disease 2019 COVID-19 Critical deep deep learning develop disease Diseases drug effective effective drugs functions identify improvement Improvements insight interpretability learning New patients Precision referred to Repurposed drug Repurposed drugs repurposing Spread the disease transmitted treat treating COVID-19 Treatment treatment strategy [DOI] 10.1109/TNNLS.2021.3111745 PMC 바로가기 [Article Type] Review