Early Virus Clearance and Delayed Antibody Response in a Case of Coronavirus Disease 2019 (COVID-19) With a History of Coinfection With Human Immunodeficiency Virus Type 1 and Hepatitis C Virus인간 면역 결핍 바이러스 1형 및 C형 간염 바이러스와의 동시 감염 이력이 있는 코로나바이러스 질병 2019(COVID-19)의 경우 조기 바이러스 제거 및 지연된 항체 반응Case Reports Published on 2020-11-192022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, [키워드] acute respiratory syndrome antibody Antibody Response Coinfection coronavirus coronavirus disease COVID-19 Delayed HCV hepatitis C highlight history HIV-1 Host Human Human immunodeficiency virus immune dysfunction Immune status Infection plasma response SARS-CoV-2 SARS-CoV-2 clearance SARS-CoV-2 RNA Type virus [DOI] 10.1093/cid/ciaa408 PMC 바로가기 [Article Type] Case Reports
Glasgow Early Treatment Arm Favirpiravir (GETAFIX) for adults with early stage COVID-19: A structured summary of a study protocol for a randomised controlled trialLetter Published on 2020-11-192022-10-29 Journal: Trials [Category] COVID-19, SARS, [키워드] 1:1 48 hours able to swallow accompany addition age Alexandra Algorithm ALT Antiviral Arm AST authority baseline Blinding Breastfeeding childbearing clinical clinically clinician co-morbidities co-morbidity Concomitant medication contribute control arm COVID COVID-19 COVID-19 infection COVID-19 test death defined dialysis disease dissemination doses drug duration of symptom early early stage effective Efficacy eight element Elizabeth EudraCT European excluded experimental arm Factor Favipiravir female females first positive greater haemofiltration Health hereditary xanthinuria history hospital hospitalisation hypersensitivity hypertension Hypothesis impairment in-patient Infection Infirmary information Inpatient ISARIC4C ISRCTN Loading dose maintenance dose male measure mechanism medication men metabolite negative number obesity objective offered open label Other outcome Outpatient Oxygen therapy parallel group participant Patient patients patients with COVID-19 pharmacokinetic pharmacokinetics Point positive pregnancy test pregnant Primary outcome principal investigator protocol random randomisation randomised randomised controlled trial Randomised trial receive recruit recruited recruitment reducing reference Registered Regulating reported risk risk of death Safety Sample size SARS-CoV-2 sequence severe hepatic impairment severity Severity of disease Sex Standard Standard of care standard treatment standard treatment alone status Study protocol Symptom the primary endpoint the WHO Tolerability Total treated Treatment treatment allocation treatment for COVID-19 Trial ULN undergo union university website WHO with COVID-19 women [DOI] 10.1186/s13063-020-04891-1 PMC 바로가기 [Article Type] Letter
Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV): A structured summary of a study protocol for a randomised controlled trialCOVID-19(ZILU-COV)로 인한 급성 저산소 호흡 부전 환자의 질루코플란: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-11-192022-08-13 Journal: Trials [Category] SARS, 임상, [키워드] 24 hour 24 hours acute hypoxic respiratory failure acute lung injury acute respiratory distress syndrome addition Adult patient alveolar pressure antibiotic Antibiotics anticipated arterial pressure Bacterial blinded Blinding Caregivers ceftriaxone characterized ciprofloxacin clinical Clinical course Combination comparator comparator Patients complement complement C5 inhibition complement pathways complement system component components control arm control group COVID-19 COVID-19 patient CT scan Cytokine release syndrome defined discharge discharged patient discharged patients disease dissemination Effect Efficacy and safety element eligibility criteria EudraCT exclusion criteria experimental arm Fungal infection history hospital discharge hospitalized patient hospitalized patients hospitals hypoxia hypoxic respiratory failure ICU ICUs Identifier improving oxygenation inclusion criteria individual Infection inhibiting inhibitor Interactive Web Response System invasive IV infusion LDH lead lung Lung injury lymphopenia Mechanical mechanical ventilation median meningococcal disease meningococcal infections number objective Open-label open-label trial outcome oxygen oxygen) Oxygenation pandemic PaO parameters Partial participant Participants Patient Phase 2 predict predisposition primary endpoint promote prophylactic antibiotics protocol randomisation randomised randomised controlled trial randomization Randomized receive recent recruited recruitment REDCap Registered repair mechanism Respiratory failure response Sample size SARS-COV-2 infection Serum ferritin SIGN SpO2 Standard of care status Study protocol subcutaneously supplemental oxygen supplementary material System systemic cytokine release syndrome Trial Trial registration Ventilation Version Web website zilucoplan [DOI] 10.1186/s13063-020-04884-0 PMC 바로가기 [Article Type] Letter
Prognostic Impact of Prior Heart Failure in Patients Hospitalized With COVID-19COVID-19로 입원한 환자의 이전 심부전의 예후 영향Article Published on 2020-11-172022-09-11 Journal: Journal of the American College of Cardiology [Category] Coronavirus, 변종, 유전자 메커니즘, [키워드] 95% confidence interval adjusted adjusted odds ratio adverse outcome adverse outcomes age aldosterone angiotensin Characteristics classification clinical Clinical characteristics conducted coronavirus coronavirus disease coronavirus disease-2019 COVID-19 described Ejection fraction Electronic health records etiology failure functional heart heart failure higher risk history hospital Hospitalized Impact in-hospital mortality increased risk inhibitor intensive care intensive care unit left ventricular ejection fraction LVEF mechanical ventilation Mortality Mount Sinai New York City Odds ratio outcome Patient patients hospitalized Renin renin-angiotensin-aldosterone system renin-angiotensin-aldosterone system inhibitor. Retrospective analysis revision System ventricular ventricular ejection with COVID-19 women [DOI] 10.1016/j.jacc.2020.09.549 PMC 바로가기 [Article Type] Article
The Natural History and Transmission Potential of Asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 Infection무증상 중증급성호흡기증후군 코로나바이러스 2 감염의 자연사 및 전파 가능성Major Articles and Commentaries Published on 2020-11-152022-09-10 Journal: Clinical Infectious Diseases: An Official Publicat [Category] MERS, SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis Asymptomatic asymptomatic individual Asymptomatic individuals Chain Reaction city clearance Clinical data collected conducted Contact coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 Coronaviruses COVID-19 detectable enrolled Enrollment faster Follow-up history Ho Chi Minh imported cases individual Infection less natural natural history NTS pandemic participant participated polymerase chain polymerase chain reaction positive Potential Probability Prospective Study quarantine respiratory Result RT-PCR RT-PCR testing Saliva saliva samples SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA Swab swabs Symptom symptomatic symptomatic individuals symptomatic participant symptomatic participants tested transmission potential Travel Vietnam Viral viral clearance Viral load virus [DOI] 10.1093/cid/ciaa711 PMC 바로가기 [Article Type] Major Articles and Commentaries
How History of Medicine Helps Us Understand COVID-19 ChallengesArticle Published on 2020-11-012023-07-06 Journal: Public health reports (Washington, D.C. : 1974) [Category] SARS, [키워드] COVID-19 history pandemic preparedness social distancing [DOI] 10.1177/0033354920961132 PMC 바로가기
Long COVID: don’t consign ME/CFS to historyComment Published on 2020-11-012023-07-11 Journal: Nature [Category] SARS, [키워드] funding history Medical research [DOI] 10.1038/d41586-020-03136-0 [Article Type] Comment
From cholera to COVID-19: How pandemics have shaped the development of anaesthesia and intensive care medicineArticle Published on 2020-11-012023-07-11 Journal: Anaesthesia and intensive care [Category] SARS, [키워드] anaesthesia cholera COVID-19 Critical care Diphtheria Ebola Epidemic history history of medicine HIV/AIDS Influenza intensive care pandemic SARS vCJD war and epidemics. [DOI] 10.1177/0310057X20969701
The Long History of Vitamin C: From Prevention of the Common Cold to Potential Aid in the Treatment of COVID-19Immunology Published on 2020-10-282022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Affect AID Athletes available data boost immunity category Cold common Concentration conditions COVID-19 Critical diabetics Effect frail elderly subjects General population Health high risk High-dose history hospitalized patients immune function immune response immune system Infection infections Inflammation Long modulate non-communicable diseases obese physiological plasma Pneumonia positive Potential prevention recommendation reduce Respiratory disease respiratory infection risk SARS-CoV2 infection significantly subgroup subject Support susceptibility Treatment treatment for COVID-19 viral infections Vitamin Vitamin C vitamin C supplementation [DOI] 10.3389/fimmu.2020.574029 PMC 바로가기 [Article Type] Immunology
Evaluation of the efficacy and safety of favipiravir and interferon compared to lopinavir/ritonavir and interferon in moderately ill patients with COVID-19: a structured summary of a study protocol for a randomized controlled trialLetter Published on 2020-10-272022-10-29 Journal: Trials [Category] COVID-19, MERS, SARS, [키워드] 1:1 Adverse drug reaction allergy allocation sequence antibody tests anticipated Arm ARMS assigned Bandar Abbas Blinding block randomization Breastfeeding carried China cirrhosis clinical Clinical improvement company Computed tomography conditions Confirmed Control control group Controlled trial COVID-19 criteria Critical Department Diagnosis dissemination dose Efficacy and safety element evaluate Favipiravir Fever FIVE generate Hepatitis history Hospital stay Hospitalization ill patient in both groups incidence India infection with SARS-CoV-2 interferon intervention group Iran liver diseases Lopinavir/ritonavir nasopharyngeal sample number objective Open-label Other outcome parallel-group participant Patient patients Phase 3 Placebo Pneumonia polymerase chain Primary outcome protocol random randomization Randomized Randomized controlled trial receive registry renal respiratory routine care RT-PCR Sample size SARS-CoV-2 screened secondary outcome single-center Study protocol treatment arm Trial trial protocol two group Viral load web-based system website X-ray Zhejiang [DOI] 10.1186/s13063-020-04747-8 PMC 바로가기 [Article Type] Letter