Safety and clinical outcomes of remdesivir in hospitalised COVID-19 patients: a retrospective analysis of active surveillance database입원 COVID-19 환자에서 Remdesivir의 안전 및 임상 결과 : 활발한 감시 데이터베이스의 후 향적 분석Research Article Published on 2022-01-042022-09-10 Journal: BMC Infectious Diseases [Category] SARS, 치료제, [키워드] Active surveillance Administered adverse event Analysis Antibiotics cardiac disease Clinical outcome clinical status Comorbidities concomitant medications conducted COVID-19 Data analysis Data collection database diabete diabetes died Factor High-flow oxygen hospitalised hospitalised patient Hospitalised patients hypertension increased liver enzyme increased liver enzymes India liver enzymes low-flow oxygen management mechanical ventilation men Mortality mortality rate nausea nausea and vomiting non-invasive ventilation oxygen Oxygen therapy Patient patients receiving Remdesivir Result Retrospective analysis Retrospective studies Safety safety profile significantly higher significantly lower steroid Steroids Subgroup analyses subgroup analysis supplementary material treatment for COVID-19 used data vomiting with COVID-19 [DOI] 10.1186/s12879-021-07004-8 PMC 바로가기 [Article Type] Research Article
The Predictive Value of Cell Blood Count Parameters to Diagnose Pulmonary Embolism in Patients with SARS-CoV-2 Infection: A Case Control StudyArticle Published on 2022-01-042022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] acute pulmonary embolism Analysis angio Biomarker Blood case control study CBC Cell Clinical practice Computed tomography conducted Control coronavirus coronavirus infectious disease-2019 correlation count COVID-19 COVID-19 patient COVID-19 patients diagnostic Embolism excluded Exploratory analysis hospitalised incidence Infection investigated Lymphocyte count material mean platelet volume Mortality mortality rate neutrophil Neutrophil-to-lymphocyte ratio NLR parameter Patient Platelet platelet-to-lymphocyte ratio Population predictor Prognosis prognostic biomarker pulmonary Pulmonary Scintigraphy Result SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome-coronavirus 2 significant difference Univariate analysis value Volume [DOI] 10.3390/antibiotics11010060 PMC 바로가기 [Article Type] Article
Impact of COVID-19 on Hospital Admissions for COPD Exacerbation: Lessons for Future CareArticle Published on 2022-01-012022-10-30 Journal: Medicina [Category] COVID-19, SARS, [키워드] Admission Admissions behavioural chronic COPD COVID-19 COVID-19 pandemic death Diagnosis driving Effect England Future hospital Hospital admission hospitalised Impact implication In-hospital lesson limit material measure Mortality Multiple no increase Obstructive oxygen pandemic Patient PCR test physical positive COVID-19 presenting pulmonary disease rates of admission reduced reduction in regression analysis Respiratory failure SARS-CoV-2 severity Transmission triggered Ventilation viral infection [DOI] 10.3390/medicina58010066 PMC 바로가기 [Article Type] Article
Ambulatory care management of 69 patients with acute severe ulcerative colitis in comparison to 695 inpatients: insights from a multicentre UK cohort study695명의 입원 환자와 비교하여 급성 중증 궤양성 대장염 환자 69명의 외래 치료 관리: 영국 다기관 코호트 연구의 통찰력Multicenter Study Published on 2022-01-012022-09-11 Journal: BMJ open gastroenterology [Category] SARS, 치료기술, [키워드] acceptability age ambulatory Ambulatory care ambulatory patient ambulatory patients Analysis Aside bowel Care Cohort cohort study cohorts colectomy collected Corticosteroid COVID-19 criteria detect Diagnosis discharged disease disease phenotype Effectiveness Eligible patients evaluated flexible flexible sigmoidoscopy Follow-up Health Service health service research hospital Hospital admission hospital management hospitalised IBD IBD clinical index Inflammatory Inflammatory bowel disease intravenous less management Mortality multicentre no significant difference no significant differences outcome outcome measure Pathways Patient patients treated performed phenotype physician post-hoc analysis Primary outcome PROTECT readmission recruited registration number required rescue secondary secondary outcome Secondary outcomes Steroids Stool culture subsequent surgery surgery for IBD therapy Treatment Treatment outcome ulcerative colitis used data [DOI] 10.1136/bmjgast-2021-000763 PMC 바로가기 [Article Type] Multicenter Study
Hospitalisation and mortality from COVID-19 in Mexican indigenous people: a cross-sectional observational studyObservational Study Published on 2022-01-012022-10-05 Journal: Journal of epidemiology and community health [Category] SARS, 임상, [키워드] 95% CI adjusted being Care Characteristics Clinical practice COVID-19 cross-sectional death Deprivation diabetes effort Ethnic groups Health healthcare higher odd higher risk hospital equipment hospitalisation hospitalised hypertension individuals inequalities laboratory-confirmed male Ministry of Health MoH morbidity Mortality obesity Older outcome outcomes Patient patients patients with COVID-19 Probability PROTECT resource SARS-CoV-2 SARS-COV-2 infection Sociodemographic used data Variation with COVID-19 [DOI] 10.1136/jech-2020-216129 PMC 바로가기 [Article Type] Observational Study
Rivaroxaban versus no anticoagulation for post-discharge thromboprophylaxis after hospitalisation for COVID-19 (MICHELLE): an open-label, multicentre, randomised, controlled trialRandomized Controlled Trial Published on 2022-01-012022-10-05 Journal: Lancet (London, England) [Category] 임상, [키워드] 1:1 95% CI allergic reaction Analysis anticoagulation assigned Asymptomatic Bayer blinded Brazil carried Clinical outcome conducted Controlled trial COVID-19 D-dimer D-dimer level death discharged Efficacy elevated eligibility enrolled FIVE Follow-up high risk hospital discharge hospitalisation hospitalised increased risk intensive care intention-to-treat intention-to-treat analysis intention-to-treat population major bleeding multicentre occurred Open-label outcome Patient patients prevention primary analysis randomised Randomised trial Randomly receive Registered registry risk rivaroxaban screened Standard dose study group symptomatic Thromboembolism Thromboprophylaxis thrombotic event Trial Two patient venous Venous Thromboembolism with COVID-19 withdrawal of consent [DOI] 10.1016/S0140-6736(21)02392-8 PMC 바로가기 [Article Type] Randomized Controlled Trial
COVID-19 hospital prevalence as a risk factor for mortality: an observational study of a multistate cohort of 62 hospitalsObservational Study Published on 2022-01-012022-10-05 Journal: BMJ Quality & Safety [Category] SARS, 임상, [키워드] 95% CI accounted adjusted Admission analysed AOR averaged Care Clinical risk factors Cohort COVID-19 COVID-19 mortality COVID-19 patient death declined evaluated health system hospital hospital medicine hospitalised increase in linear mixed model Mortality mortality (standardised mortality ratios). multivariable analysis pandemic Patient patients with COVID-19 Prevalence prevalence of COVID-19 Probability random effect remained risk factor SARS-COV-2 infection Support Volume with COVID-19 [DOI] 10.1136/bmjqs-2021-013721 PMC 바로가기 [Article Type] Observational Study
Thrombosis-related circulating miR-16-5p is associated with disease severity in patients hospitalised for COVID-19혈전증 관련 순환 miR-16-5p는 COVID-19로 입원한 환자의 질병 중증도와 관련이 있습니다Article Published on 2022-01-012022-09-11 Journal: RNA Biology [Category] 바이오마커, [키워드] 95% CI ACE2 ACE2 receptor activated acute respiratory syndrome acute respiratory syndrome coronavirus Admission amyloid amyloid beta Analysis angiotensin Angiotensin-converting enzyme app approach Area baseline baseline expression Beta bioinformatic analysis bioinformatics Bioinformatics analysis Biomarker Blood Blood cells body mass CALM1 calmodulin can be used changes in chronic obstructive circulating class Co-expression analysis Coagulation composite endpoint condition Control Coronary artery coronavirus coronavirus disease Coronavirus infection COVID-19 COVID-19 complications COVID-19 patient cyclin dataset death diabete diabetes Diabetes Mellitus diagnostic disease disease severity EGFR ELAVL1 enzyme expression expression level expression levels expressions family Fibronectin Filamin FLNA FN1 Follow-up Gene Expression Genes growth factor healthy controls healthy volunteer heat Heat shock heat shock protein hospital hospitalised hospitalized COVID-19 patient HSP90AA1 Human hypercoagulable in silico in silico prediction independent predictor independent predictors individual inflammatory reaction intensive care interquartile let-7b-5p Like member microRNA MicroRNAs miR-155 miR-16-5p miRNA miRNAs Multivariate analysis Myocardial nuclear pathway Pathways Patient patients hospitalized patients with COVID-19 performed peripheral Peripheral blood phosphatase play role polymerase chain positive Predictive prognostic biomarker Prognostic biomarkers Protein PTEN qRT-PCR Quantitative receptor Regulatory RNA SARS-CoV-2 selected Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Severity of infection silico prediction silico predictions Stratification tensin the healthy THROMBOPLASTIN thrombosis thrombotic Toll-like receptor TP53 UBC ubiquitin utility White blood cells [DOI] 10.1080/15476286.2022.2100629 PMC 바로가기 [Article Type] Article
Outcomes of Ayurvedic care in a COVID-19 patient with hypoxia – A case reportCase report Published on 2022-01-012022-10-05 Journal: Journal of Ayurveda and Integrative Medicine [Category] 신약개발, [키워드] Administered administration anorexia Asymptomatic Ayurveda breathing difficulty Care Case report chills Clinical improvement cough COVID-19 COVID-19 patient CRP discharged drug fatigue Fever headache high risk hospital hospitalised hypoxia indicated integrative medicine Intervention Loss of Smell loss of taste Medicine nasal obesity outcome oxygen support Oxygen therapy Patient plasma positive presenting progression remained RT-PCR SARS CoV 2 severe disease symptomatic tested Treatment Vitamin [DOI] 10.1016/j.jaim.2020.10.006 [Article Type] Case report
SARS-CoV-2 infection among hospitalised pregnant women and impact of different viral strains on COVID-19 severity in Italy: a national prospective population-based cohort study입원한 임산부의 SARS-CoV-2 감염과 이탈리아의 COVID-19 심각도에 대한 다양한 바이러스 균주의 영향: 국가 전향적 인구 기반 코호트 연구Article Published on 2022-01-012022-09-11 Journal: BJOG : an international journal of obstetrics and [Category] SARS, 변종, [키워드] 95% CI Admission age Asymptomatic Birth rate citizenship clinician Cohort Cohort studies Comorbidity country COVID-19 COVID-19 disease COVID-19 illness COVID-19 pneumonia COVID-19 severity death described Hospital admission hospitalised hospitals ICU ICU admission intensive care intensive care unit Italian Italy Maternal maternal age Migration mode multivariate analyses National Neonatal Neonatal Mortality obesity Occurrence outcome outcomes Pneumonia population-based cohort Pregnancy pregnant women Preterm birth prospective cohort study remained reported required Research risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral severe COVID-19 disease severe COVID-19 illness severity significant increase Stillbirth strain ventilatory support viral strain virus variant virus variants wild-type women [DOI] 10.1111/1471-0528.16980 PMC 바로가기 [Article Type] Article