A one-step, one-pot CRISPR nucleic acid detection platform (CRISPR-top): Application for the diagnosis of COVID-19원스텝, 원팟(one-pot) CRISPR 핵산 검출 플랫폼(CRISPR-top): 코로나19 진단을 위한 애플리케이션Article Published on 2021-10-012022-09-11 Journal: Talanta [Category] SARS, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplification application applied can be used Cas12b causative agent clinic clinical sample clinical samples clinically collected complexity Contamination coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CRISPR CRISPR-Top cross-contamination cross-reactivity detect diagnosis of COVID-19 diagnostic diagnostic test diagnostic tests DNA followed by Frame increase Laboratory lateral flow limit of detection Non-COVID-19 nucleic acid Nucleic acid detection ORF1ab performed platform positive positive result primary care reaction risk RNA RT-PCR SARS-CoV-2 SARS-CoV-2 detection severe acute respiratory syndrome Coronavirus specificity swab samples target temperature These data [DOI] 10.1016/j.talanta.2021.122591 PMC 바로가기 [Article Type] Article
SARS-CoV-2 among inmates aged over 60 during a COVID-19 outbreak in a penitentiary complex in Brazil: Positive health outcomes despite high prevalence브라질의 교도소 단지에서 COVID-19 발생 중 60세 이상 수감자 중 SARS-CoV-2: 높은 유병률에도 불구하고 긍정적인 건강 결과Article Published on 2021-10-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Asymptomatic Brazil Care case finding Chain Reaction Comorbidities complex contributed coronavirus COVID-19 COVID-19 outbreak death District evaluated Federal District Health health condition health monitoring hospitalisation measure outbreak outcome outcomes Periodic Polymerase chain reaction testing positive positive result Post-infection Prevalence prisons promote Public public health Rapid test reported symptoms reverse transcriptase SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Surveillance symptomatic symptomatic patient Symptomatic patients Symptoms was performed were infected were recorded [DOI] 10.1016/j.ijid.2021.03.080 PMC 바로가기 [Article Type] Article
Prevalence of SARS-CoV-2 infection in the workplace: results of a year of investigation in the Marche Nord companies직장 내 SARS-CoV-2 감염 유병률: Marche Nord 기업에서 1년 동안 조사한 결과Article Published on 2021-10-012022-09-11 Journal: Acta bio-medica : Atenei Parmensis [Category] SARS, 치료기술, [키워드] activate activity adoption affected association carried close contact contact with COVID-19 pandemic Ct value diagnostic E gene Health highlight IgG IgM immunochromatographic test Infection Internal control Marche measure multiplex Nasopharyngeal swab observation Pesaro positive positive result protocols rapid serological test Rapid serological tests RdRP real-time RT-PCR RNA RNase P SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection SARS-CoV-2 virus Serological tests Spread Support Swab tested the SARS-CoV-2 the SARS-CoV-2 virus Total total RNA transmission of SARS-CoV-2 university Urbino Viral RNA was performed Workplace [DOI] 10.23750/abm.v92iS6.12238 PMC 바로가기 [Article Type] Article
Mild and Asymptomatic COVID-19 Convalescents Present Long-Term Endotype of Immunosuppression Associated With Neutrophil Subsets Possessing Regulatory Functions경증 및 무증상 COVID-19 회복기 조절 기능을 보유한 호중구 하위 집합과 관련된 면역 억제의 장기 엔도타입 제시Immunology Published on 2021-09-292022-09-11 Journal: Frontiers in Immunology [Category] SARS, 진단, 치료기술, [키워드] activated addition affecting Analysis anti-CD3 anti-SARS-CoV-2 Asymptomatic Asymptomatic COVID-19 asymptomatic infection autologous Blood Cancer CD8 Cell Complication Concentration convalescent convalescent sera coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 convalescents described disease elevated endotype enrolled expansion FACS function functions GM-CSF granulocyte-macrophage colony stimulating factor (GM-CSF) Granulocytic granulocytic myeloid-derived suppressor cells (PMN-MDSCs) healthy donor IgG immune response Immunosuppression immunosuppressive Infection inhibit long-COVID low-density low-density neutrophils (LDNs) lymphopenia mAb Mild myeloid cell myeloid cells NDN Neutralizing Neutralizing antibodies neutrophil neutrophil dysfunction Neutrophils normal density neutrophils past PCR test PD-L1 positive result present proliferation Propagation Regulatory responsible SARS-CoV-2 SARS-COV-2 infection serum sample serum samples severe lymphopenia significantly higher subpopulation suppressor cells T cell T cells T-cell tendency These cells was used were used Whole blood [DOI] 10.3389/fimmu.2021.748097 PMC 바로가기 [Article Type] Immunology
Performance of anti-SARS-CoV-2 antibody testing in asymptomatic or mild COVID-19 patients: A retrospective study in outbreak on a cruise ship무증상 또는 가벼운 CovID-19 환자에서 항 -SARS-COV-2 항체 검사의 성능 : 유람선 발병에 대한 후 향적 연구Research Article Published on 2021-09-282022-09-10 Journal: PLoS ONE [Category] SARS, 진단, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgM antibody Antibody responses Antibody testing Antibody titer Antibody titers Asymptomatic blood sample Blood samples collected coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic COVID-19 patient Cruise ship Diagnosis electrochemiluminescence immunoassay ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated false-negative Follow-up Genetic Genetic testing IgG antibodies IgG antibody IgM antibodies IgM antibody immunochromatographic assay initial lateral flow lateral flow immunochromatographic assay Mild mild COVID-19 patient mild COVID-19 patients nucleocapsid objective outbreak Patient performance positive result required respiratory responses Result Retrospective study Sample SARS-CoV-2 significantly lower specificity Spike protein Spike proteins the patient titer titers total antibodies total antibody used to evaluate was performed were measured [DOI] 10.1371/journal.pone.0257452 PMC 바로가기 [Article Type] Research Article
Factors affecting duration of SARS-Cov-2 viral shedding in mildly symptomatic patients isolated in a community facilityResearch Article Published on 2021-09-272022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] affecting age Asymptomatic baseline Characteristics clinical collected Community Comorbidities Comorbidity concomitant medications consecutive patient CRP cut-off Factor feature identify individual Infection interquartile range Isolation laboratory investigation majority median Mild mildly symptomatic patient negative RT-PCR objective Patient patients positive result radiologic raised required Result retrospective cohort study SARS-CoV-2 RNA viral Swab symptomatic symptomatic case symptomatic COVID-19 systematic analysis Tachycardia Taking Transmission vector viral shedding vital signs [DOI] 10.1371/journal.pone.0257565 PMC 바로가기 [Article Type] Research Article
Risk factors for recurrent positive results of the nucleic acid amplification test for COVID-19 patients: a retrospective study코로나19 환자에 대한 핵산 증폭 검사에서 반복적으로 양성 반응을 보이는 위험인자: 후향적 연구Research Article Published on 2021-09-232022-09-12 Journal: Human Cell [Category] MERS, 진단, [키워드] 95% CI Bilirubin Child chloride Concentration contribute cough coughing COVID-19 Dyspnea Factor first positive groups help Hospital stay Hospitalization identify increased risk Incubation period independent risk factor Isolation Maternal Multivariable regression analysis NAAT Negative retest nucleic acid amplification nucleic acid amplification tests Patient positive positive result Positive retest potassium concentration presenting proportion public health reduce Retrospective study SARS-CoV-2 serum Surveillance symptom onset Transmission with COVID-19 [DOI] 10.1007/s13577-021-00618-9 PMC 바로가기 [Article Type] Research Article
Network assessment and modeling the management of an epidemic on a college campus with testing, contact tracing, and maskingResearch Article Published on 2021-09-172022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] assumed average average path calculated Clustering college Community Compliance Contact tracing Course degree disease transmission distribution Effectiveness Efficacy Enrollment Epidemic epidemic peak Epidemics Factor Frequency high-density implication individuals infections Interaction Intervention liberal management network positive result Probability proportion random reducing SARS-CoV-2 Simulation skewed Spread student Test the disease USA was tested were assessed were used [DOI] 10.1371/journal.pone.0257052 PMC 바로가기 [Article Type] Research Article
A single dose of the Biontech/Pfizer BNT162b2 vaccine protected elderly residents from severe COVID‐19 during a SARS‐coronavirus‐2 outbreak in a senior citizen home in GermanyShort Report Published on 2021-09-162022-10-30 Journal: Immunity, Inflammation and Disease [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Antigen asymptomatic individual BNT162b2 BNT162b2 vaccine Bremen coronavirus COVID‐19 COVID‐19 symptoms dose Effectiveness first dose Germany Hospitalized infected individual infections Lineage Local Mild mild symptoms outbreak PCR positive positive result prevented processes reported Result RT‐PCR SARS‐CoV‐2 SARS‐CoV‐2 genome single dose single vaccine tested vaccination Vaccine viral/retroviral [DOI] 10.1002/iid3.532 PMC 바로가기 [Article Type] Short Report
The utilization of hydroxychloroquine to reduce the main signs and symptoms of COVID-19 patients, a cross-sectional studyCase-controlled Study Published on 2021-09-162022-10-04 Journal: Annals of Medicine and Surgery [Category] 신약개발, 치료제, [키워드] accumulate Acidic alkaline all subject analyzed Area Area under the curve (AUC) Arm Asymptomatic COVID-19 AUC benefit body temperature breath cell membranes cells Chloroquine clinical trial Concentration coronavirus cough COVID-19 COVID-19 patient COVID-19 positive patient cross-sectional Diagnosis effective Efficacy evaluate Fever Follow-up function HCQ Hydroxychloroquine inclusion criteria increase Infection Loading dose lysosome Lysosomes maintenance dose no significant effect non-randomized objective Open-label participant Patient patients penetrate positive positive result presenting Prevent receive reduce reducing Result severe disease Shortness of breath statistically subject Symptom symptomatic symptoms of COVID-19 Trial two groups utilization variable Viral load were used while [DOI] 10.1016/j.amsu.2021.102867 PMC 바로가기 [Article Type] Case-controlled Study