Early Phases of COVID-19 Are Characterized by a Reduction in Lymphocyte Populations and the Presence of Atypical MonocytesImmunology Published on 2020-12-092022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] 28-day mortality acute respiratory syndrome Admission association Atypical CD14 CD3+ CD4+ cell CD8+ Cell cells characterized composed coronavirus coronavirus disease COVID-19 Diagnosis died early phase evaluated expression HLA-DR Immune profile immune profiling immunological change include Infection Inflammation Inflammatory biomarker IQR lymphocyte lymphocytopenia mean value median value monocyte Monocytes mononuclear cell mononuclear cells natural killer pathogen patients patients with COVID-19 Peripheral blood Peripheral blood mononuclear cells phase Population Presence preserved reduced reduction responsible Result SARS-CoV-2 side scatter subpopulation [DOI] 10.3389/fimmu.2020.560330 PMC 바로가기 [Article Type] Immunology
Alignment of virus-host protein-protein interaction networks by integer linear programming: SARS-CoV-2Research Article Published on 2020-12-072022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] aligned alignment Analysis carried caused Consensus coronavirus coronavirus SARS-CoV-2 COVID-19 Drug discovery effort functional human protein Infection Infectious disease lack linear motivation new virus pandemic preserved programming protein-protein interaction Research Result SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 proteins Scientific community similarity viral infection virus replication Virus-host interactions [DOI] 10.1371/journal.pone.0236304 PMC 바로가기 [Article Type] Research Article
Metabolic impact of weight loss induced reduction of adipose ACE-2 – Potential implication in COVID-19 infections?Randomized Controlled Trial Published on 2020-12-012022-10-05 Journal: Metabolism: clinical and experimental [Category] SARS, 임상, [키워드] ACE-2 adipose Adipose tissue Affect age analyzed angiotensin BMI cell entry changes in characterized Clamp control group COVID-19 downregulation enzyme expression Glucose improvement insulin insulin resistance Insulin sensitivity Intervention ISI liver metabolic metabolism modulation mRNA expression not affected obesity Potential predicted preserved Randomized receptor reduction Regulation responsible SARS-CoV-2 sensitivity Skeletal muscle subject subjects tissue tissue metabolism Trial was measured was reduced weight weight loss [DOI] 10.1016/j.metabol.2020.154401 PMC 바로가기 [Article Type] Randomized Controlled Trial
No Evidence of SARS-CoV-2 Circulation in Rome (Italy) during the Pre-Pandemic Period: Results of a Retrospective SurveillanceArticle Published on 2020-11-162022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] acute respiratory syndrome affected both viruses characterized collected coronavirus country COVID-19 COVID-19 outbreak COVID-19 pandemic Critical detectable Diagnostic method epidemiological and etiological surveillance evaluated evidence of health authorities hospital in some infection prevalence Influenza influenza-like syndrome investigated investigator Italian Italy Laboratory Local Nasopharyngeal swab pandemic Patient Pneumonia positive preserved radiological recorded reported Result Rome routine monitoring SARS-CoV-2 SARS-CoV-2 RT-PCR Spread Study protocol syndrome tested the SARS-CoV-2 virus WHO with COVID-19 World Health Organization [DOI] 10.3390/ijerph17228461 PMC 바로가기 [Article Type] Article
Peripheral Neuropathy as a Complication of SARS-Cov-2Internal Medicine Published on 2020-11-122022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Analysis Awareness baseline Brain C-reactive protein cerebrospinal fluid Clinical outcome Complication Copper deficiency Corticosteroid cough COVID-19 creatinine kinase CSF described Diagnosis early treatment elevated lactate dehydrogenase fatigue fevers FIVE Guillain-barrè syndrome healthy intravenous Intravenous immunoglobulin lack magnetic resonance imaging management Methylprednisolone Mild myalgia nasal congestion neurologic neurological manifestation Neurological symptoms Neuropathy onset of symptoms Pain Patient patients peripheral Peripheral Neuropathy positive post-viral preserved replaced reported respiratory symptom SARS-CoV-2 serum shown sore throat spinal fluid steroid symptomatic improvement tested Treatment unlikely vitamin B6 was done weakness [DOI] 10.7759/cureus.11452 PMC 바로가기 [Article Type] Internal Medicine
COVID-19: through the eyes through the front line, an international perspectiveMeeting Report Published on 2020-11-072022-10-28 Journal: Antimicrobial Resistance and Infection Control [Category] Coronavirus, SARS, [키워드] absence addition ancestor average Care Centralized control COVID-19 COVID-19 virus death Disparities Efficiency eye globe Government greater healthcare Healthcare system highest Infection International Lock downs Mask Masks misinformation Netherlands Other pandemic Pandemics Personal protective equipment Personal rights Personnel protection equipment Perspective PPE preparation preserved prevented provided public health recommendation risk SARS-CoV-2 severe deficiency Singapore social distancing Spain Strategic stockpile the United State The United States United States worker safety [DOI] 10.1186/s13756-020-00850-2 PMC 바로가기 [Article Type] Meeting Report
Rescue therapy with inhaled nitric oxide and almitrine in COVID-19 patients with severe acute respiratory distress syndromeResearch Published on 2020-11-042022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] acute respiratory distress Almitrine ARDS association baseline Blood caused Combination Compliance conducted COVID-19 COVID-19 patient evaluate females hemodynamic highlight hypoxic increase in Inhaled iNO intubated patient male mechanism median median age nitric oxide no correlation Oxygenation PaO pathophysiology Patient patients performed pilot study preserved primary endpoint proning rescue respiratory Respiratory system Result severe COVID-19 severe hypoxemia syndrome therapy Variation vascular dysfunction Vascular function vasoconstriction were assessed [DOI] 10.1186/s13613-020-00769-2 PMC 바로가기 [Article Type] Research
Serum-IgG responses to SARS-CoV-2 after mild and severe COVID-19 infection and analysis of IgG non-responders경증 및 중증 COVID-19 감염 후 SARS-CoV-2에 대한 혈청-IgG 반응 및 IgG 무반응자 분석Research Article Published on 2020-10-212022-08-13 Journal: PLoS ONE [Category] COVID-19, Medicine and Health Sciences, MERS, SARS, [키워드] Abbott Abbott Laboratories Abbott Laboratory age Analysis antibody Antibody titers Architect clinically Cohort cohort of patient Concentration COVID-19 COVID-19 patient detectable develop female Follow-up house iFlash IgG IgG antibodies IgG antibody IgG level IgG responses Immunity imperative Interpretation knowledge median Mild Mild symptom mild symptoms Neutralizing antibodies non-responder Nucleocapsid proteins Patient preserved quantified Receptor binding remained response Result SARS-CoV-2 SARS-CoV-2-specific IgG Seroconversion seroconvert seroconverted Serological assay seronegative serum severe COVID-19 Severe COVID-19 Infection severe symptom severe symptoms severity of symptoms significantly shorter specific IgG antibodies spike and nucleocapsid proteins spike-protein symptom onset time virus-neutralizing antibodies virus-neutralizing antibody [DOI] 10.1371/journal.pone.0241104 PMC 바로가기 [Article Type] Research Article
Abnormal left ventricular global longitudinal strain by speckle tracking echocardiography in COVID-19 patientsCOVID-19 환자의 반점 추적 심초음파 검사에 의한 비정상적인 좌심실 전체 세로 변형Short Communication Published on 2020-10-092022-09-12 Journal: Future Cardiology [Category] MERS, SARS, 진단, [키워드] Abstract Affect affected cardiovascular system Cell Cohort coronavirus COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients determine died discharge discharged Ejection Ejection fraction eyes fraction healthy heart muscle Implications Infection LVEF material measure myocardial strain imaging no correlation no significant difference outcome Patient patients who survived patients with COVID-19 preserved prognostic significantly lower Speckle tracking echocardiography Survivors the patient transthoracic echocardiography ventricular was measured was reduced [DOI] 10.2217/fca-2020-0121 PMC 바로가기 [Article Type] Short Communication
The stroke mothership model survived during COVID-19 era: an observational single-center study in Emilia-Romagna, ItalyCovid-19 Published on 2020-10-082022-10-30 Journal: Neurological Sciences [Category] Coronavirus, MERS, SARS, [키워드] Admissions adopted Care center Cohort combined treatment COVID-19 COVID-19 pandemic demographic factor Effect Emilia-Romagna Epidemiology high variability hospital Hospitalization hospitalizations Ischemic Stroke Italy less Logistic no difference pandemic Patient patients preserved prevalent proportion reduced reduction reperfusion reported Result retrospective significantly single-center study slight increase stroke survived to define Transient ischemic-attack Treatment [DOI] 10.1007/s10072-020-04754-2 PMC 바로가기 [Article Type] Covid-19