respiratory diseases – Page 15 – Communicable Diseases Research

Therapeutic Potential of Mesenchymal Stem Cells and Their Products in Lung Diseases—Intravenous Administration versus Inhalation

Review

Published on 2021-02-072022-10-28
Journal: Pharmaceutics [Category] COVID-19,

ECIEN-2020 study: the effect of COVID-19 on admissions for non-COVID-19 diseases

Observational Study

Published on 2021-02-012022-10-05
Journal: World Journal of Pediatrics [Category] 임상,

[키워드] Admission Admissions adopted affecting age analyzed average caused center Characteristics conducted coronavirus disease COVID-19 COVID-19 pandemic described disease Diseases duration of symptoms Effect Epidemiology First wave health system highlight Hospital admission Hospitalization intensive care measure Non-COVID-19 pandemic past medical history Pathologies Patient pediatric percentage preventive measure pulmonary diseases reduction in Respiratory Coronavirus respiratory diseases SARS-CoV-2 Sex significant changes in significantly Spain Symptoms tertiary referral hospital was performed
[DOI] 10.1007/s12519-020-00406-9 PMC 바로가기 [Article Type] Observational Study

COVID-19 and active primary tuberculosis in a low-resource setting: A case report

Case report

Published on 2021-02-012022-10-05
Journal: Annals of Medicine and Surgery [Category] 신약개발,

Mucociliary Respiratory Epithelium Integrity in Molecular Defense and Susceptibility to Pulmonary Viral Infections

Review

Published on 2021-01-292022-10-28
Journal: Biology [Category] COVID-19,

[키워드] acute respiratory disease acute respiratory syndrome airways arising Bearing Cell cellular and molecular changes in chronic respiratory disease ciliary ciliated ciliated cells clearance coronavirus Coronavirus disease-19 Coronavirus-2 COVID-19 Defense develop directional disrupt driven by dysfunction elicit epithelial epithelium Genetic goblet cells Health healthy help host infection Human implication include individual Infection integrity Interaction involved lethal infection lung lung cilia maintain management MCC mechanism microbial infection microbial infections molecular molecular component Mucociliary clearance Mucus nasopharynx novel virus pandemic pathogen pathophysiology Patient predicted Protein pulmonary Pulmonary function regulate respiratory Respiratory disease respiratory diseases respiratory epithelium Respiratory system respiratory tract SARS-CoV-2 viral simple Surveillance susceptible transcriptional
[DOI] 10.3390/biology10020095 PMC 바로가기 [Article Type] Review

Unraveling the Interconnection Patterns Across Lung Microbiome, Respiratory Diseases, and COVID-19

Cellular and Infection Microbiology

Published on 2021-01-282022-10-31
Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS,

[키워드] characteristic contributed COVID-19 disease Genome sequencing Gut Health healthy individuals Immunity influence interconnection intestinal knowledge lung lung immunity lung in health and disease Lung microbiome lung-gut axis methodology microbial Microbiome microbiota Pathogenesis pattern progression provide reported respiratory Respiratory disease respiratory diseases SARS-CoV-2 thought
[DOI] 10.3389/fcimb.2020.619075 PMC 바로가기 [Article Type] Cellular and Infection Microbiology

The Central Role of Fibrinolytic Response in COVID-19—A Hematologist’s Perspective

COVID-19에서 섬유소 용해 반응의 중심 역할 - 혈액 전문의의 관점

Review

Published on 2021-01-282022-09-12
Journal: International Journal of Molecular Sciences [Category] 진단,

[키워드] ACE acute respiratory diseases acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome aldosterone angiotensin angiotensin-converting enzyme 2 ARDS balance Characteristics contagious coronavirus coronavirus disease cough Course COVID-19 drug target Evidence fatigue Fever fibrinolysis fibrinolytic fibrinolytic system headache host cells hypercoagulable Hypercoagulable state Infection inhibitor involved kidney lesion lesions lung MERS Middle East Middle East respiratory syndrome Novel coronavirus novel coronavirus disease other organ other organs Pathogenesis pathway patients with COVID-19 plasminogen activator inhibitor 1 (PAI-1) pulmonary complications RAAS receptor Renin renin-aldosterone-angiotensin-system (RAAS) respiratory respiratory diseases respiratory distress Respiratory distress syndrome respiratory tract infection response role SARS-CoV-2 Severe acute respiratory syndrome severe pneumonia sore throat Spike protein spike protein of SARS-CoV-2 syndrome the spike protein tissue plasminogen activator Transmission uPA Urokinase-Type Plasminogen Activator Viral viral illnesses
[DOI] 10.3390/ijms22031283 PMC 바로가기 [Article Type] Review

Clinical features and natural history of the first 2073 suspected COVID-19 cases in the Corona São Caetano primary care programme: a prospective cohort study

Infectious Diseases

Published on 2021-01-122022-10-28
Journal: BMJ Open [Category] COVID-19, Fulltext, MERS,

[키워드] Ageusia Anosmia arthralgia assist Brazil Care clinical Clinical data Community consecutive patient Corona cough COVID-19 COVID-19 case COVID-19 cases cycle threshold death Diagnosis Epidemiology Fatality rate fatigue feature Fever finding hospital hospitalisation hospitalised Infection Infectious diseases men Mild Most patient myalgia obesity offered Older age older patients Patient platform population-based cohort positive COVID-19 positive patient presenting primary care prospective cohort study public health respiratory diseases RT-PCR SARS-CoV-2 serology serology testing seropositive severe cases Symptom symptom onset tested transcriptase Virological with COVID-19
[DOI] 10.1136/bmjopen-2020-042745 PMC 바로가기 [Article Type] Infectious Diseases

Antiviral activity of lambda-carrageenan against influenza viruses and severe acute respiratory syndrome coronavirus 2

인플루엔자 바이러스 및 중증급성호흡기증후군 코로나바이러스 2에 대한 람다-카라기난의 항바이러스 활성

Article

Published on 2021-01-122022-09-10
Journal: Scientific Reports [Category] 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration Antiviral antiviral activity antiviral agent body weight broad spectrum cause Cell culture cell lysate cell lysates cell surface receptor cell surface receptors circulating Concentration coronavirus culture supernatant culture supernatants dose-dependent manner Drug discovery enveloped RNA viruses expression host cell host cells Influenza influenza A Influenza virus inhibited intranasal lambda-carrageenan macromolecule mice Microbiology Mortality plaque Plaque titration polysaccharide preventing infection progeny purified reduced reductions in respiratory respiratory diseases respiratory viruses RNA viruses SARS-CoV-2 severe acute respiratory syndrome Coronavirus sulfated suppressed Toxicity Viral viral challenge Viral protein Viral proteins virus virus entry virus production viruses western blot Western blot analysis
[DOI] 10.1038/s41598-020-80896-9 PMC 바로가기 [Article Type] Article

Genetic Dissection of the Regulatory Mechanisms of Ace2 in the Infected Mouse Lung

Immunology

Published on 2021-01-082022-11-01
Journal: Frontiers in Immunology [Category] COVID-19,

[키워드] ACE2 ACE2 sequence acute lung injury Analysis analyzed approaches Bayesian Body weight loss BXD family caused chromosome core Coronaviruses defined disease disease risk disease severity Dissection enzyme epithelial cells expression expression level function gene co-expression network gene product H1N1 Hierarchical Host host response identify include Infection Influenza influenza A virus lung Lung infection Lung injury MAPK membrane-bound MERS-CoV mice modulate molecular morbidity and mortality mouse mRNA level network analysis outcome parental participated potential therapeutic target primary human airway Protein pulmonary quantified respiratory diseases RNA-Seq SARS-CoV SARS-CoV-2 Sepsis severity signaling pathways significantly strain TNF transcript Transcriptome variant viral infection viral infections Viral load viremia network weight loss WGCNA
[DOI] 10.3389/fimmu.2020.607314 PMC 바로가기 [Article Type] Immunology

A structured summary of a study protocol for a multi-center, randomized controlled trial (RCT) of COVID-19 prevention with Kampo medicines (Integrative Management in Japan for Epidemic Disease by prophylactic study: IMJEDI P1 study)

Kampo 의약품을 사용한 COVID-19 예방에 대한 다기관, 무작위 대조 시험(RCT) 연구 프로토콜의 구조화된 요약(예방 연구에 의한 전염병에 대한 일본의 통합 관리: IMJEDI P1 연구)

Letter

Published on 2021-01-062022-08-31
Journal: Trials [Category] MERS, 임상, 치료제,

[키워드] 1:1 administration age allergic Analysis appearance Arm ARMS assumed Asymptomatic balancing Blinding body temperature calculated capture cardiovascular disease Chain Reaction clinical clinical trials cloud condition Control control group cough COVID-19 diabetes disappearance dissemination doctor dosage dropout rate drug edema effective element Endpoint exclusion criteria failure Fever Final final analysis final analysis) Frequency group hands healthy history hospital Hospitalization hypertension hypokalaemia Hypothesis ICU Immunosuppressant immunosuppressants incidence of COVID-19 incidence rate incidence rates include inclusion criteria Infection infection rate Inflammation interim analysis interstitial pneumonia intervention group investigator Japan Japanese Kampo Kampo medicines liver dysfunction lung malaise management mechanical ventilation Medicine number numbness objective observation period oral administration oral administration) outcome package parallel-group participant Patient PCR PCR positive per day Period pharmaceutical Placebo placebo group Placebo tablets positive result power power of 80% pregnant Prevent Prophylactic prophylactic study protocol randomised Randomized Randomized controlled trial RCT receive recruited Registered Registration registry required Research respiratory respiratory diseases respiratory inflammation risk factor Risk factors Safety Sample size SARS-CoV-2 RNA secondary Secondary outcomes Shock Shortness of breath significantly skin rash sputum study drug study period Study protocol supplementary material Symptom Symptoms symptoms of COVID-19 Tablet Taking Taste the placebo group Trial Trial registration Two-arm university upper respiratory verification Viral viral infection Vital website
[DOI] 10.1186/s13063-020-04939-2 PMC 바로가기 [Article Type] Letter