SARS

[키워드] acetyl active site Amino acid amino acid residue Analysis antiviral activity caused Characteristics characterized Concentration concentrations contributed coronavirus COVID-19 demonstrated derivative Drug discovery Efficacy enzyme evaluated exhibited Host host cells hydrogen Hydrogen bond hydrogen bonds hydrolysis in vitro ingredient inhibit inhibitor inhibitors inhibitory inhibitory activity Juglone M pro M(pro) inhibitors molecular docking studies much higher naphthoquinone Naphthoquinones non-toxic outbreak peptide polyprotein positive control positive-sense single-stranded RNA protease proteinase Replication replication of SARS-CoV-2 Research RNA coronavirus SARS SARS-CoV-2 significantly suppress tested Transcription Vero E6 Vero E6 cell VERO E6 cells Viral virus
[DOI] 10.1016/j.ejmech.2021.113789 PMC 바로가기 [Article Type] Article