Clinical utility of targeted SARS-CoV-2 serology testing to aid the diagnosis and management of suspected missed, late or post-COVID-19 infection syndromes: Results from a pilot service implemented during the first pandemic wave코로나19 감염 후 의심되는 누락, 후기 또는 사후 감염 증후군의 진단 및 관리를 지원하기 위한 표적 SARS-CoV-2 혈청 검사의 임상적 유용성: 첫 번째 유행성 유행 기간 동안 구현된 파일럿 서비스의 결과Clinical Trial Published on 2021-04-072022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 임상, 진단, 치료기술, 치료제, [키워드] anti-spike antibodies anti-spike antibody antibodies benefit Care central London Characteristics children clinical clinical utility COVID-19 COVID-19 pandemic defined detect detectable diagnose diagnoses Diagnosis experience feasibility First wave followed by help hospital Immunosuppression indication indications individual Infection infection control Interpretation Intervention lateral flow immunoassay LFIA LFIAs management pandemic participant Patient PCR positive performed positive individual practicality Probability provided Pulmonary embolism required Result SARS-CoV-2 SARS-CoV-2 RNA serological Serological assay serological assays Serological testing serology serology testing serum service specificity Surescreen triggered urgency utility were recorded [DOI] 10.1371/journal.pone.0249791 PMC 바로가기 [Article Type] Clinical Trial
Back to normal; serological testing for COVID‐19 diagnosis unveils missed infectionsShort Communication Published on 2021-03-252022-10-04 Journal: Journal of medical virology [Category] SARS, 진단, 치료법, 치료제, [키워드] acute respiratory syndrome Algorithm back Blood coronavirus coronavirus disease COVID‐19 COVID‐19 Diagnosis diagnostic eight evaluate gold standard heterogenous IgG IgM immunofluorescence assay Immunoglobulin Infection Infectious disease median median age NAAT nucleic acid amplification nucleocapsid protein offer Patient patients Pneumonia positive Result RNA SARS‐CoV‐2 SARS‐CoV‐2 Seroconversion serologic tests serological Serological testing serology testing symptom onset tested the spike protein viral tropism [DOI] 10.1002/jmv.26949 PMC 바로가기 [Article Type] Short Communication
Epidemiological analysis of a COVID-19 outbreak associated with an infected surgeonShort Paper Published on 2021-03-252022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, [키워드] activity Analysis applied Asymptomatic Contact Control COVID-19 COVID-19 outbreak hcp Head and neck surgery Healthcare professional hospital Hospital infection household contact IgM In-hospital occur Otorhinolaryngology outbreak Patient performed Personal protective equipment positive quarantine recommendation remained risk SARS-CoV-2 serological test Serological testing subject surgeon surgical Surgical procedures swabs Symptom tested transmission of SARS-CoV-2 [DOI] 10.1017/S0950268821000650 PMC 바로가기 [Article Type] Short Paper
Diagnostic Value of IgM and IgG Detection in COVID-19 Diagnosis by the Mobile Laboratory B-LiFE: A Massive Testing Strategy in the Piedmont Region모바일 연구소 B-LiFE에 의한 COVID-19 진단에서 IgM 및 IgG 검출의 진단적 가치: 피에몬테 지역의 대규모 테스트 전략Article Published on 2021-03-242022-09-10 Journal: International Journal of Environmental Research an [Category] SARS, 진단, 치료기술, 치료법, [키워드] acute infectious disease age Analysis antibodies asymptomatic individual Asymptomatic individuals Care caused Cohort consequence coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19 cases COVID-19 outbreak detect detection detection rate Diagnosis domain emerging biological threats first responders Health Health care help IgG IgM and IgG individual Infectious disease Italy Laboratory Large-scale testing massive Mobile moderate Novel coronavirus nucleocapsid protein performed Piedmont police positively correlated Prevalence professionals Protein Public Health Preparedness RBD protein Region residence responders S-RBD SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 NP antibody SARS-CoV-2 spike SARS-CoV-2 spike receptor-binding domain Seroconversion seroconverted Serological testing Seroprevalence serum serum antibodies serum antibody Sex Strategy Surveillance Testing the SARS-CoV-2 value volunteers Whole blood [DOI] 10.3390/ijerph18073372 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Infection and Antibody Response in a Symptomatic Cat from Italy with Intestinal B-Cell Lymphoma장 B 세포 림프종이 있는 이탈리아의 증상이 있는 고양이의 SARS-CoV-2 감염 및 항체 반응Case Reports Published on 2021-03-232022-09-01 Journal: Viruses [Category] SARS, 진단, 치료기술, [키워드] ( RdRP acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 anti-SARS-CoV-2 antibody assumption B-cell lymphoma best cats Chain Reaction clinical condition clinical disease Clinical signs close contact Comorbidities Comorbidity companion animal condition contact with coronavirus coronavirus disease Coronavirus-2 cough COVID-19 detectable discharge disease domestic cat envelope Evidence gastrointestinal disease Human human-to-feline transmission IgG Immunoglobulin Infection intestinal investigated Italy knowledge molecular Neutralizing activity ocular oropharyngeal swab pandemic polymerase chain polymerase chain reaction positive provide RBD RdRP real-time reverse transcriptase Receptor binding domain reported respiratory respiratory tract response reverse transcriptase Reverse transcriptase polymerase chain reaction RNA-dependent RNA polymerase RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral RNA Serological testing serology Seropositivity severe acute respiratory syndrome Coronavirus sneeze susceptible sVNT tested Transmission Viral Virus neutralization [DOI] 10.3390/v13030527 PMC 바로가기 [Article Type] Case Reports
Clustering and longitudinal change in SARS-CoV-2 seroprevalence in school children in the canton of Zurich, Switzerland: prospective cohort study of 55 schools스위스 취리히 주의 학교 아동에서 SARS-CoV-2 혈청 유병률의 클러스터링 및 종단적 변화: 55개 학교의 전향적 코호트 연구Article Published on 2021-03-172022-09-11 Journal: The BMJ [Category] Fulltext, SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age children class Clustering cohort study Community community transmission coronavirus credible interval determine diagnosed District Europe explained Health highest increase in Keeping logistic regression models longitudinal change longitudinal changes moderate no significant differences occurred outcome pandemic parent parents participated preventive measure Prospective prospective cohort study provided questionnaire Questionnaires Randomly reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 pandemic SARS-CoV-2 seroprevalence School Schools second wave selected serological result serological results Serological testing serology serology test serology tests seronegative seropositive Seropositivity Seroprevalence severe acute respiratory syndrome Coronavirus significant difference Sociodemographic stratified summer Switzerland Symptom the SARS-CoV-2 transmission of SARS-CoV-2 Uncertainty variance variants of SARS-CoV-2 [DOI] 10.1136/bmj.n616 PMC 바로가기 [Article Type] Article
Genetic testing and serological screening for SARS-CoV-2 infection in a COVID-19 outbreak in a nursing facility in Japan일본의 한 요양시설에서 코로나19 발생 시 SARS-CoV-2 감염에 대한 유전자 검사 및 혈청학적 스크리닝Research Article Published on 2021-03-152022-09-01 Journal: BMC Infectious Diseases [Category] 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antibody test Antibody testing antibody tests Asymptomatic caused Combination conducted coronavirus coronavirus disease COVID-19 COVID-19 outbreak Critical Dementia died epicenter evaluated Fever Genetic healthcare personnel impacted individual individuals infected individuals Infection Japan Mortality Nasopharyngeal swab nasopharyngeal swabs Negative PCR number of infected Nursing facility outbreak PCR PCR positivity PCR testing PCR-positive performed prevalent quantitative assay respiratory Result SARS-CoV-2 SARS-COV-2 infection serological serological test Serological testing Serological tests severe acute respiratory syndrome Coronavirus Spread supplementary material termination unit [DOI] 10.1186/s12879-021-05972-5 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 Testing of 11,884 Healthcare Workers at an Acute NHS Hospital Trust in England: A Retrospective AnalysisMedicine Published on 2021-03-122022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Asymptomatic Bame clinical cohorts Community contributing to COVID-19 dataset deaths demographic factor Deprivation England estimates Factor foundation groups HCW HCWs health-care healthcare worker healthcare workers (HCWs) hospital Hospitalization ICU Increased increased risk increases in Infection infection levels infection with SARS-CoV-2 logistic regression model management NHS Nosocomial infection Nurses occupational risk analysis and management outcome PCR testing positive Retrospective analysis risk robust SARS-CoV-2 SARS-CoV-2 IgG Seroconversion Serological testing Seropositivity statistically significant symptomatic Testing Trust with COVID-19 worker [DOI] 10.3389/fmed.2021.636160 PMC 바로가기 [Article Type] Medicine
Evaluation of the effect of melatonin in patients with COVID-19-induced pneumonia admitted to the Intensive Care Unit: A structured summary of a study protocol for a randomized controlled trial중환자실에 입원한 COVID-19 유발 폐렴 환자에서 멜라토닌의 효과 평가: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-03-082022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 ABG allergy allocation sequence anticipated Arm ARMS arterial blood arterial blood gas Bandar Abbas Blinding block randomization Blood blood gas Breastfeeding C-reactive protein C-RP clinical clinical symptom Clinical symptoms clinical trial clinical trials company comparator conducted Control control group COVID-19 criteria Definitive definitive diagnosis diagnosis of COVID-19 disease Diseases disorders dissemination dose Effect element feature ferritin gelatin generate history ICU inclusion criteria Inflammation intensive care unit intervention group Iran Laboratory Lactate lactate dehydrogenase LDH lung involvement mechanical ventilation melatonin Ministry of Health mortality rate number objective Open-label open-label trial outcome parallel-group participant Participants Patient patients pharmaceutical Pharmaceutical Company Placebo Pneumonia Pregnancy Primary outcome Primary outcomes protocol random randomization randomize Randomized Randomized controlled trial regimen Registered registration date registration number registry renal RT-PCR Sample size screened secondary outcome Secondary outcomes Serological testing Seven severe pneumonia severely ill patient severely ill patients single-center standard treatment status Study protocol supplementary material therapeutic Trial trial protocol Trial registration twice a day underlying diseases Version web-based system website [DOI] 10.1186/s13063-021-05162-3 PMC 바로가기 [Article Type] Letter
The Conundrum of Giglio Island: Unraveling the dynamics of an apparent resistance to COVID-19 – A descriptive studyResearch Article Published on 2021-03-022022-10-31 Journal: Computational and Structural Biotechnology Journal [Category] COVID-19, [키워드] 2019-nCoV Abstract acid Asymptomatic asymptomatic infection baseline carried Cohort conducted COVID-19 cross-reactivity develop Endemic female Giglio Island hypotheses IgM island Italy Local male median age molecular analysis NAAT objective occurred positive positive result Prevalence protective factor Rapid test Result risk RT-qPCR Saliva SARS-CoV-2 SARS-CoV-2 seroprevalence serologic serological Serological testing subject Symptom Test viruses was performed [DOI] 10.1016/j.csbj.2021.02.008 PMC 바로가기 [Article Type] Research Article