Invasive pulmonary aspergillosis in critically ill patients with severe COVID-19 pneumonia: Results from the prospective AspCOVID-19 study중증 COVID-19 폐렴이 있는 중환자의 침습성 폐 아스페르길루스증: 전향적 AspCOVID-19 연구 결과Research Article Published on 2021-03-172022-09-10 Journal: PLoS ONE [Category] SARS, 치료기술, [키워드] affected age Analysis APACHE II score approach both groups bronchial lavage clinical parameter Clinical parameters Cohort collected Combination Complication controls COVID-19 COVID-19 cohort COVID-19 pneumonia Critically ill Critically ill patient critically ill patients defined diagnosed diagnostic early stage evaluate finding galactomannan help high mortality rate ICU ICU admission identify incidence invasive Invasive pulmonary aspergillosis IPA Laboratory Logistic regression Logistic regression analyses matched controls mechanical ventilation median Mortality not different outcome Patient Pneumonia prevalent pulmonary aspergillosis regression analysis Result risk factor Risk factors screened severe COVID-19 Severe COVID-19 pneumonia severe viral pneumonia Study protocol timepoint Viral Viral pneumonia Virological [DOI] 10.1371/journal.pone.0238825 PMC 바로가기 [Article Type] Research Article
Successful pulsed methylprednisolone and convalescent plasma treatment in a case of a renal transplant recipient with COVID-19 positive pneumonia: a case reportCase Report Published on 2021-03-162022-10-28 Journal: The Pan African Medical Journal [Category] COVID-19, MERS, [키워드] Affect cadaver Case report caused convalescent plasma Convalescent plasma therapy convalescent plasma treatment cough COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients death disease Fever FIVE Follow-up immunosuppressive male Methylprednisolone Moderate COVID-19 mortality rate Patient performed plasma Pneumonia positive presenting protocol pulse steroid therapy radiological improvement recipient recipients renal Renal transplantation Respiratory system Severe COVID-19 pneumonia Shortness of breath specific treatment therapy Thorax tomography Treatment with COVID-19 Wuhan, China [DOI] 10.11604/pamj.2021.38.273.28577 PMC 바로가기 [Article Type] Case Report
Tocilizumab improves survival in severe COVID-19 pneumonia with persistent hypoxia: a retrospective cohort study with follow-up from Mumbai, IndiaTocilizumab, 지속적인 저산소증이 있는 중증 COVID-19 폐렴의 생존율 향상: 인도 뭄바이에서 추적 관찰한 후향적 코호트 연구Observational Study Published on 2021-03-052022-09-01 Journal: BMC Infectious Diseases [Category] SARS, 신약개발, 임상, 진단, [키워드] 95% CI addition analysed Analysis Care China CO-RADS control group Controlled trial controlled trials controls coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 admission COVID-19 cytokine storm COVID-19 patient COVID-19 pneumonia Cox regression analysis CT-severity score cytokine Cytokine storm death defined FiO2 Follow-up high mortality hospital hyperinflammatory state Hyperinflammatory syndrome hypoxia IBM IL-6 IL-6 receptor IMPROVE independent predictor independent predictors India Interlukin-6 intravenously less log rank median minute monoclonal antibody Mortality multivariate multivariate Cox regression multivariate Cox regression analysis Mumbai non-rebreathing mask observational study oxygen oxygen saturation paO2/fiO2 PaO2/FiO2 ratio Patient predictor reported Result retrospective retrospective cohort study saturation severe coronavirus disease Severe COVID-19 pneumonia significantly SPSS standard care statistical analysis supplemental oxygen survival therapy Tocilizumab Treatment triggered was performed [DOI] 10.1186/s12879-021-05912-3 PMC 바로가기 [Article Type] Observational Study
Mobile-Assisted Virtual Bonding Enables Breast Milk Supply in Critically Ill Mothers With COVID-19: A Reflection on the Feasibility of TelelactationObstetrics/Gynecology Published on 2021-03-042022-10-31 Journal: Cureus [Category] COVID-19, [키워드] addition Anxiety auditory bonding Breast Breastfeeding coronavirus disease COVID -19 COVID-19 Critically ill E-health ENhance generate Health hospital Ill impair involved Iran lactation milk Mobile health mother Newborn newborn infant offered offspring outcome pandemic Reflection Severe COVID-19 pneumonia shown supply telehealth telelactation [DOI] 10.7759/cureus.13699 PMC 바로가기 [Article Type] Obstetrics/Gynecology
Tracheal Tube Obstruction Due to Hemoptysis Associated With Pulmonary Infarction in a Patient With Severe COVID-19 PneumoniaEmergency Medicine Published on 2021-02-272022-10-31 Journal: Cureus [Category] COVID-19, [키워드] accompanied acute respiratory syndrome Admission Anticoagulant anticoagulant therapy Blood Case report coronavirus COVID-19 Cytokine storm decrease Diagnosis discharged Disseminated intravascular coagulation dropped eight endotracheal tube excessive immune response extracorporeal membrane oxygenation Factor hemoptysis hospital Hypoxemia hypoxic incidence Infarction Inflammation initiated intensive care Intubated Japanese obstruction oxygen saturation PaO Patient patients with COVID-19 Pharyngeal swab positive pulmonary pulmonary embolism (PE) risk of infection severe coronavirus disease Severe COVID-19 pneumonia suction suggested Support tested the patient thrombotic complication Thrombotic complications tracheal tube tube ventilator Volume VV-ECMO were used [DOI] 10.7759/cureus.13599 PMC 바로가기 [Article Type] Emergency Medicine
Auto-antibodies against type I IFNs are associated with severe COVID-19 pneumoniaI형 IFN에 대한 자가 항체는 심각한 COVID-19 폐렴과 관련이 있습니다Comment Published on 2021-02-262022-09-12 Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, MERS, 진단, [키워드] Infectious diseases Severe COVID-19 pneumonia Type I IFN [DOI] 10.1038/s41392-021-00514-6 PMC 바로가기 [Article Type] Comment
Clonal expansion and activation of tissue-resident memory-like T H 17 cells expressing GM-CSF in the lungs of patients with severe COVID-19중증 COVID-19 환자의 폐에서 GM-CSF를 발현하는 조직 상주 기억 유사 T H 17 세포의 클론 확장 및 활성화Research Article Published on 2021-02-232022-09-12 Journal: Science Immunology [Category] Fulltext, MERS, 진단, [키워드] Activation acute respiratory distress acute respiratory distress syndrome Analysis Autoimmune diseases Bacterial bacterial pneumonia BAL Blood Bronchoalveolar lavage Bronchoalveolar lavage fluid CD8 Cell cell type cells cellular characterized Clinical course clonal expansion clone Cohort cohort of patient collected contribute coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia CSF2 cytokine cytokine expression profile disease severity elevated expressing feature Generation GM-CSF helper high mortality hyperinflammation identify IL-17A IL17A Immune cell immune cell type immune cells immune response Immunopathogenesis interactome investigated involved lung lung damage Lung injury Lung pathology lung tissue Lungs Macrophage macrophages mechanism memory T cell moderate disease pathogenic Patient patients with COVID-19 Pneumonia protein level pulmonary T respiratory distress Respiratory distress syndrome serum severe coronavirus disease severe COVID-19 Severe COVID-19 pneumonia single-cell subsequent syndrome T cell T cell response T cells T helper TCR Th17 cells Therapies tissues Transcriptome Viral viral clearance viral infection [DOI] 10.1126/sciimmunol.abf6692 PMC 바로가기 [Article Type] Research Article
Bowel necrosis in patient with severe case of COVID-19: a case reportCase Report Published on 2021-02-222022-10-28 Journal: BMC Surgery [Category] COVID-19, MERS, [키워드] bowel Bowel necrosis Case report COVID-19 Critically ill general surgery high mortality rate manifestation Manifestations Necrosis Patient Severe case Severe COVID-19 pneumonia the disease was performed with COVID-19 [DOI] 10.1186/s12893-021-01104-7 PMC 바로가기 [Article Type] Case Report
Long-term sero-positivity for IgG, sequelae of respiratory symptoms, and abundance of malformed sperms in a patient recovered from severe COVID-19심각한 COVID-19에서 회복된 환자에서 IgG에 대한 장기 혈청 양성, 호흡기 증상의 후유증 및 기형 정자 풍부Case Reports Published on 2021-02-082022-09-12 Journal: European Journal of Clinical Microbiology & Infect [Category] MERS, SARS, 진단, [키워드] Affect airway Antiviral Chest Chest CT chest pain China collected cough Course COVID-19 Hypoxemia IgG Immunoglobulin Infection Laboratory Lung function morphology nocturnal Patient Pneumonia positive Quality of life rehabilitation Reproductive function Respiratory function respiratory problem respiratory symptoms severe coronavirus disease severe COVID-19 Severe COVID-19 pneumonia Sex hormones Shortness of breath sleep apnea suffered syndrome Treatment [DOI] 10.1007/s10096-021-04178-6 PMC 바로가기 [Article Type] Case Reports
Clinical Characteristics and Outcome of Patients With Severe COVID-19 Pneumonia at a Public Sector Hospital in Karachi, PakistanAnesthesiology Published on 2021-02-032022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Absolute lymphocyte count accounted Acute kidney injury acute respiratory distress acute respiratory syndrome Administered Admission age ARDS average Benazir Bhutto C-reactive protein cardiac complication clinical Clinical characteristics co-morbidities co-morbidity comorbid conditions complications conducted confirmed case coronavirus COVID COVID-19 Critical CRP CRS Cytokine release syndrome death demographics develop disease Factor Fever Final hospital hypertension intensive care unit Karachi lack LDH leukocyte males mechanical ventilation median moderate Mortality MOST neutrophil lymphocyte ratio NIV NLR non-invasive ventilation Non-survivors Odds ratio Older age on mechanical ventilation outcome Pakistan parameter Patient patients patients died patients with COVID-19 PCR peaked Platelet Pneumonia polymerase chain positive predominant public sector reported SARS-CoV2 Sepsis Severe COVID-19 pneumonia Shortness of breath statistically significant Steroids survival analysis Survivors Symptom syndrome the median Tocilizumab was done [DOI] 10.7759/cureus.13107 PMC 바로가기 [Article Type] Anesthesiology