HLA-C*04:01 Affects HLA Class I Heterozygosity and Predicted Affinity to SARS-CoV-2 Peptides, and in Combination With Age and Sex of Armenian Patients Contributes to COVID-19 SeverityHLA-C*04:01 SARS-CoV-2 펩티드에 대한 HLA 클래스 I 이형접합 및 예측된 친화도에 영향을 미치고 아르메니아 환자의 연령 및 성별과 함께 COVID-19 심각도에 기여Immunology Published on 2022-02-032022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] 95% CI advanced age affinity affinity to SARS-CoV-2 age Antigen Armenian population Armenians association Asymptomatic Asymptomatic COVID-19 AUC carriers change class contribute contributed Control COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 severity COVID-19 susceptibility decrease deficiency demographic variable disease severity disease symptom distribution dose-dependent manner Effect examined Frequency Genotype Health heterozygosity HLA HLA allele HLA classical genes HLA-B HLA-B*51:01 HLA-C HLA-C*04:01 HLA-C*04:01 allele HLA-I heterozygosity homozygous Hospitalization host immunity incidence Infection Interaction leukocyte loci Male sex outcome Patient patients peptide Personalized medicine predicted Prevalence Protective provided recognize risk SARS-CoV-2 SARS-CoV-2 coronavirus SARS-CoV-2 peptides severe COVID-19 severity severity risk modelling Sex significant increase significantly subgroup the disease the SARS-CoV-2 translated Variability [DOI] 10.3389/fimmu.2022.769900 PMC 바로가기 [Article Type] Immunology
Effects of laser acupuncture tele-therapy for rheumatoid arthritis elderly patientsRandomized Controlled Trial Published on 2022-02-012022-10-05 Journal: Lasers in medical science [Category] COVID19(2023년), SARS, 임상, [키워드] 1:1 addition aerobic antioxidant approach Arthritis assigned ATP autoimmune disorder C-reactive protein (CRP COVID-19 pandemic CRP disease disorder Effect effective elderly Elderly patient functional Geriatrics group Health Assessment IL-6 Inflammatory marker interleukin-6 Laser Laser acupuncture marker MDA methotrexate oxidative Patient physical Prognosis questionnaire Randomly reduction Rheumatoid rheumatoid arthritis significant increase significantly statistically significant statistically significant difference Tele-rehabilitation the patient treated Treatment [DOI] 10.1007/s10103-021-03287-0 PMC 바로가기 [Article Type] Randomized Controlled Trial
The Detrimental Impact of the COVID-19 Pandemic on Major Trauma Outcomes in the Netherlands: A Comprehensive Nationwide StudyObservational Study Published on 2022-02-012022-10-05 Journal: Annals of surgery [Category] COVID19(2023년), SARS, 임상, [키워드] addition admitted to ICU adverse effect analyses average Brain Care caused Comprehensive COVID-19 COVID-19 pandemic evaluate hospital ICU ICUs Impact increased mortality Injury less Major major trauma moderate Mortality mortality rates multivariable logistic regression Netherlands Observational cohort study outcome Patient predicted registry resource severity significant increase trauma trauma patient treated was performed was recorded [DOI] 10.1097/SLA.0000000000005300 PMC 바로가기 [Article Type] Observational Study
Anti-SARS-CoV-2 mRNA vaccines as inducers of humoral response against apolipoprotein A-1?Apolipoprotein A-1에 대한 체액 반응의 유도제로서의 Anti-SARS-CoV-2 mRNA 백신?Article Published on 2022-02-012022-09-12 Journal: European Journal of Clinical Investigation [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] AAA1 Affect anti-SARS-CoV-2 anti-SARS-CoV-2 mRNA vaccines anti-SARS-CoV-2 vaccine apolipoprotein A-1 association autoantibodies Autoimmune Autoimmune response baseline Biomarker collected components COVID-19 density first vaccination fraction healthy control healthy controls humoral IgG IgG level IgG response immunoassays individual individuals induce inducer injection lipoprotein Local median mRNA vaccine mRNA-based observé outcomes Patient patients Population populations Prognosis Protein protocol raised recipient retrieved rheumatoid arthritis SARS-CoV-2 second vaccination serology shown significant increase Symptom systemic translate vaccination were measured were recorded [DOI] 10.1111/eci.13713 PMC 바로가기 [Article Type] Article
Effects of COVID-19 pandemic on intensive rehabilitation after severe acquired brain injuriesObservational Study Published on 2022-02-012022-10-05 Journal: Neurological Sciences [Category] COVID19(2023년), SARS, 임상, [키워드] Admission affected Brain case mix Clinical data Cohort collected component COVID-19 COVID-19 pandemic decrease discharge disorder Disorders of consciousness Effect functional health emergency health system Hemorrhagic Stroke Injury Intensive material median age median time pandemic Patient reduction rehabilitation Retrospective study Severe acquired brain injuries. Side-effect significant increase [DOI] 10.1007/s10072-021-05709-x PMC 바로가기 [Article Type] Observational Study
COVID-19 and dys-regulation of pulmonary endothelium: implications for vascular remodelingReview article Published on 2022-02-012022-10-05 Journal: Cytokine & growth factor reviews [Category] COVID19(2023년), SARS, 바이오마커, 치료기술, [키워드] Activation affected Angiogenesis Biomarker blood vessels caused claimed clinical manifestation connection COVID-19 COVID-19 pathogenesis Cytokine storm distress endothelial cells Endotheliitis Endothelium Evidence facilitate feature Functional respiratory imaging implication indicated infect Inner Intussusceptive angiogenesis kidney lack limit limitation liver lung mechanical ventilation Non-invasive organ overcome patients with COVID-19 priming rapid process recent reported required significant increase spike glycoprotein splitting the disease thrombosis TMPRSS2 unique Vascular Vascular remodeling vasoconstriction vessel viral entry virus [DOI] 10.1016/j.cytogfr.2021.10.003 [Article Type] Review article
COVID-19 outcomes of patients with gynecologic cancer in New York City: An updated analysis from the initial surge of the pandemicObservational Study Published on 2022-02-012022-10-05 Journal: Gynecologic oncology [Category] Coronavirus, 임상, [키워드] 95% confidence interval acute respiratory syndrome age Analysis anti-cancer treatment association Black race Cancer Chemotherapy Cohort Comorbidity coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 complications COVID-19 diagnosis COVID-19 hospitalization COVID-19 infection death Diagnosis Factor Fatality rate Gynecologic cancer hospital Hospitalization hospitalized patients ICU admission increased risk Infection initial interquartile range Invasive mechanical ventilation IQR Logistic regression malignancy mechanical ventilation Mortality multivariable analysis New York New York City Odds ratio oncology patient outcome outcomes pandemic Patient patients died performance status Predictive required SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) significant increase smoking survived the median therapy with COVID-19 [DOI] 10.1016/j.ygyno.2021.12.004 PMC 바로가기 [Article Type] Observational Study
COVID-19 in Southeast Asia: current status and perspectives동남아시아의 COVID-19: 현황 및 전망Review Published on 2022-02-012022-09-11 Journal: Bioengineered [Category] COVID19(2023년), SARS, 변종, [키워드] activities activity acute respiratory syndrome Alpha Asia B.1.1.529 B.1.1.7 B.1.351 B.1.617.2 Beta catastrophic closure common variants coronavirus 2 coronavirus disease coronavirus disease-2019 country Coverage COVID-19 COVID-19 situation COVID-19 vaccination COVID-19 vaccine damages Delta distribution Economy Effect green infections Medical resources Occurrence omicron Omicron variant outbreak pandemic Perspective perspectives. Prevent public health regions respiratory SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significant increase social distancing Southeast Asia Spread threat Threats Vaccine variant variants of concern virus variants VOCs zone [DOI] 10.1080/21655979.2022.2031417 PMC 바로가기 [Article Type] Review
Efficacy of lopinavir–ritonavir combination therapy for the treatment of hospitalized COVID-19 patients: a meta-analysisMeta-Analysis Published on 2022-01-312022-10-31 Journal: Future Virology [Category] COVID-19, [키워드] adverse events Antiviral benefit body temperature Clinical use combination therapy control group COVID-19 demonstrated Efficacy Efficacy and safety evaluate hospitalized COVID-19 hospitalized COVID-19 patient hospitalized COVID-19 patients incidence lack Lopinavir Lopinavir–ritonavir material mechanical ventilation meta-analyses Meta-analysis Mortality observational study outcome outcomes Randomized Ritonavir SARS-CoV-2 SARS-CoV-2 test significant increase therapy Treatment [DOI] 10.2217/fvl-2021-0066 PMC 바로가기 [Article Type] Meta-Analysis
Organ donation in the time of COVID-19: the Israeli experience one year into the pandemic—ethical and policy implicationsOriginal Research Article Published on 2022-01-312022-10-30 Journal: Israel Journal of Health Policy Research [Category] COVID-19, SARS, [키워드] addressed admitted to ICU Brain center changes in collected COVID-19 COVID-19 pandemic death Deceased decrease Donor donors emotional health-care hospital Hospitalized ICU implication Implications information Interaction kidney limitation Living kidney donation National NTC organ Organ donation pandemic Patient Registered resources Result significant increase significantly Support Transplant transplantation [DOI] 10.1186/s13584-022-00519-8 PMC 바로가기 [Article Type] Original Research Article