A Novel Bacterium-Like Particle Vaccine Displaying the MERS-CoV Receptor-Binding Domain Induces Specific Mucosal and Systemic Immune Responses in MiceArticle Published on 2019-08-292022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] acute respiratory illness bacterium-like particles binding activity candidate vaccine cellular displaying domain enhancer fusion protein GEM Human humoral immune response infections intestinal tract intranasal administration intranasally Lactococcus linker Local MERS-CoV MERS-CoV RBD mice Middle East motif mucosal mucosal immune New coronavirus novel outbreak Particle Prevent PROTECT Protein raised RBD respiratory syndrome coronavirus response Specific substrate Subunit vaccine systemic tested the RBD Vaccine were used [DOI] 10.3390/v11090799 PMC 바로가기 [Article Type] Article
Salmonella Typhi outer membrane protein STIV is a potential candidate for vaccine development against typhoid and paratyphoid feverarticle Published on 2019-05-312024-09-01 Journal: Immunobiology [Category] 살모넬라증, [키워드] Cell mediated immune response humoral immune response paratyphoid Salmonella enterica serovar Paratyphi Salmonella enterica serovar Typhi STIV Subunit vaccine typhoid [Article Type] article
Evaluation of the protective effect of immunization spf DBA/2J mice with selected bacterial, recombinant Hsp60 antigens during Salmonella Enteritidis challengearticle Published on 2019-03-312024-09-01 Journal: Microbial Pathogenesis [Category] 살모넬라증, [키워드] experimental challenge Hsp60 Recombinant protein Salmonella Enteritidis Subunit vaccine [Article Type] article
[High expression and immunogenicity analysis of HA globular head domain of H5 subtype avian influenza virus produced in Pichia pastoris]Article Published on 2019-01-252023-06-22 Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology [Category] 조류인플루엔자, [키워드] H5N1 influenza viruses hemagglutinin Pichia pastoris Subunit vaccine [DOI] 10.13345/j.cjb.180142
Pathogenicity and immunogenicity of attenuated porcine epidemic diarrhea virus PC22A strain in conventional weaned pigsResearch Article Published on 2019-01-112022-10-28 Journal: BMC veterinary research [Category] Coronavirus, MERS, [키워드] adjuvant Administered age antibody Antibody Response cause caused Cell culture cells diarrhea Efficacy elicit epidemic diarrhea evaluated fecal genetics greater group IgA IgG inactivated induce inoculated intestinal Live attenuated vaccine mortality rate mucosal immune mucosal immunity multiple dose naïve Neonatal Neutralizing PEDV porcine epidemic diarrhea virus (PEDV) post inoculation pregnant priming regimen response Result resulting RNA Safe serum subunit Subunit vaccine supplementary material tested The United States vaccination Vaccine vaccine candidates Viral RNA Viral RNA shedding virulent virus Weaned pigs [DOI] 10.1186/s12917-018-1756-x PMC 바로가기 [Article Type] Research Article
Cost-effectiveness of vaccination of immunocompetent older adults against herpes zoster in the Netherlands: a comparison between the adjuvanted subunit and live-attenuated vaccines네덜란드에서 면역력이 있는 노인에 대한 대상포진 백신 접종의 비용 효과성: 보조제가 포함된 서브유닛 백신과 생백신의 비교Research Article Published on 2018-12-062023-05-22 Journal: BMC Medicine [Category] Fulltext, 대상포진, 수두, 홍역, [키워드] cost-effectiveness herpes zoster live-attenuated vaccine Post-herpetic neuralgia Subunit vaccine vaccination [DOI] 10.1186/s12916-018-1213-5 PMC 바로가기 [Article Type] Research Article
Transcriptional response to a prime/boost vaccination of chickens with three vaccine variants based on HA DNA and Pichia-produced HA proteinComparative Study Published on 2018-11-012023-06-21 Journal: Developmental and comparative immunology [Category] 조류인플루엔자, [키워드] chicken DNA vaccine Heterologous prime/boost vaccination Influenza Spleen transcriptome Subunit vaccine [DOI] 10.1016/j.dci.2018.07.001 [Article Type] Comparative Study
Human β-defensin 2 plays a regulatory role in innate antiviral immunity and is capable of potentiating the induction of antigen-specific immunityResearch Published on 2018-08-082022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] activate Activation Adaptive immune response adaptive immune responses addition adjuvant AMP AMPs antibody Antigen antimicrobial peptide Antiviral antiviral immunity cells chemokine Defense dendritic cells domain effective elicited expressed expression expression level HBD Human Human β-defensin IFN-β IFN-γ IL-1β IL-6 immune Immunity immunization in vitro in vivo innate antiviral immunity innate immune innate immune response Innate immunity investigated leukocytes MERS-CoV mice microorganisms Middle East monocytes/macrophages Natural killer cells Neutralizing antibody response NOD2 PKR promote RBD Regulatory Research Result S RBD Spike protein Subunit vaccine suggested T cells THP-1 TNF-α treat Treatment viruses was used β-defensin [DOI] 10.1186/s12985-018-1035-2 PMC 바로가기 [Article Type] Research
Development of multi-epitope driven subunit vaccine in secretory and membrane protein of Plasmodium falciparum to convey protection against malaria infectionArticle Published on 2018-07-162024-08-28 Journal: Vaccine [Category] 말라리아, [키워드] adjuvant Artemisinin Epitopes malaria Subunit vaccine TLR-4 agonist. [DOI] 10.1016/j.vaccine.2018.05.082
Protection against Virulent Infectious Bronchitis Virus Challenge Conferred by a Recombinant Baculovirus Co-Expressing S1 and N ProteinsArticle Published on 2018-06-272022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] age antibody baculovirus booster bronchitis candidate vaccine CD4+ CD8+ T lymphocyte CD8+ T lymphocytes challenge co-expressing control vaccine demonstrated develop dose evaluated FIVE IBV IBV infection immune protection imperative Infectious Bronchitis Virus kidney morbidity Mortality N protein percentage protection recombinant Safe specific pathogen-free SPF subunit Subunit vaccine Trachea Vaccine vaccine strain Vaccines virulent virus was used [DOI] 10.3390/v10070347 PMC 바로가기 [Article Type] Article