The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases
Research Article
[키워드] 229E
activated
applied
binding
Cathepsins
CD81
CD9
Cell
cell entry
cell lines
cell membranes
cellular receptors
cleaved
Clustering
co-expressed
complex
complexes
coronavirus
CoV
CoV infection
CoVs
demonstrated
Dipeptidyl peptidase 4
DPP4
endosome
evaluate
Evolution
Express
facilitate
facilitated
Gene Expression
host cell receptor
human CoV
human DPP4
in vivo
Infection
infections
initiate
interactions
less
Lungs
membrane
membrane fusion
MERS-CoV
MERS-CoV entry
MERS-CoV infection
MERS-CoV pseudovirus
mice
Pathogens
pathway
promote
protease
Proteases
Protein
protein complex
proteolytic cleavage
receptor
recombinant adenovirus
robust
S proteins
selective
significantly
small RNA
susceptible
the S protein
TMPRSS2
transducing
transmembrane protein
transmembrane serine protease
TTSP
TTSPs
vector
vectors
viral spike
virulence
virulent
virus
virus entry
virus infection
virus-cell membrane fusion
[DOI] 10.1371/journal.ppat.1006546 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.ppat.1006546 PMC 바로가기 [Article Type] Research Article