From Wuhan to COVID-19 Pandemic: An Up-to-Date Review of Its Pathogenesis, Potential Therapeutics, and Recent AdvancesReview Published on 2020-06-042022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] advance antiparasitic drug antiviral agent Antiviral agents approach Asymptomatic individuals Blood Chloroquine clinical trial conducted contagious coronavirus COVID-19 develop disease effective Evolution FDA-approved drug genomic sequencing in silico inactivation indicated investigated life-threatening molecular docking Novel coronavirus pandemic pathogen Pathogenesis pathogenicity Potential prevention public health recent recent finding respiratory tract infection review SARS-CoV-2 Scientific community shown survival therapeutic therapeutic advances Therapeutics Transmission Transmission routes Virtual screening Wuhan [DOI] 10.3390/microorganisms8060850 PMC 바로가기 [Article Type] Review
Increased Risk of COVID-19-Related Deaths among General Practitioners in ItalyCommunication Published on 2020-06-032022-10-31 Journal: International journal for equity in health [Category] COVID-19, [키워드] affected approach asymptomatic patients available data Characteristics close contact Contagion COVID-19 COVID-19 pandemic COVID-19-related death death case effective general practitioner General practitioners highlight Increased information Italy knowledge lockdown measure National Novel coronavirus occupational medicine occurred Patient patients persistence Personal protective equipment physician Physicians Practitioner Prevent proportion risk of infection SARS-COV-2 infection SARS-CoV-2 transmission survival the epidemic transmitted [DOI] 10.3390/healthcare8020155 PMC 바로가기 [Article Type] Communication
Guidance for the care of neuromuscular patients during the COVID-19 pandemic outbreak from the French Rare Health Care for Neuromuscular Diseases NetworkPractice guideline Published on 2020-06-012022-10-05 Journal: Revue neurologique [Category] SARS, 유전자 메커니즘, [키워드] absence acute respiratory syndrome adaptation Administered Admission adopted Affect asked assessment cardiorespiratory Care caused concerning conditions coronavirus COVID-19 COVID-19 pandemic COVID-19 treatments criteria Degradation detrimental diagnostic Diseases eligible FAQ France French Guidance guidelines homogenize Hospitalization ICU implementation intensive care limit management manifestation measure National network Neuromuscular neuromuscular disease NIV Noninvasive ventilation outbreak pathology Patient patients patients treated positive Prognosis provided QT prolongation question risk SARS-CoV-2 Support survival the epidemic the patient Treatment website [DOI] 10.1016/j.neurol.2020.04.004 [Article Type] Practice guideline
The association between treatment with heparin and survival in patients with Covid-19Article Published on 2020-05-312022-10-30 Journal: Journal of Thrombosis and Thrombolysis [Category] Coronavirus, MERS, [키워드] 95% CI added adjusted Admission age age and gender association associations Clinical data clinician Combination Community Controlled trial Coronavirus infections covariate COVID-19 died discharged home drug Effect Gender heparin hospital hospitals Hydroxychloroquine IQR logistic regression model lower mortality Mortality oseltamivir oxygen Patient patients Pulmonary embolism recorded remained required Ritonavir Spain Steroids survival temperature therapeutic regime thrombosis Tocilizumab transferred Treatment variable were used [DOI] 10.1007/s11239-020-02162-z PMC 바로가기 [Article Type] Article
Why does COVID-19 disproportionately affect older people?Review Published on 2020-05-312022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, MERS, SARS, [키워드] acute respiratory distress Affect age aging cardiovascular disease Coagulopathy consolidation coronavirus disease cough COVID-19 COVID-19 patient Cytokine release syndrome Cytokine storm death diabete Dyspnea Endotheliitis epigenetic clock explain fatal disease Fever genetic test greater Hospitalization identify immune responses Immunity independent risk factor individual Infection inhibiting life-threatening lung mechanism mechanisms mild illness molecular multiple organ failure obesity Older outcome regulate risk risk of death severity survival syndrome the disease Treatment virus [DOI] 10.18632/aging.103344 PMC 바로가기 [Article Type] Review
Innate Immune Signaling and Proteolytic Pathways in the Resolution or Exacerbation of SARS-CoV-2 in Covid-19: Key Therapeutic Targets?Immunology Published on 2020-05-282022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] “cytokine storm” ACE2 activating Activation Affect affecting alveolar epithelial cells angiotensin-converting enzyme 2 Anti-viral Cathepsins caused cellular entry cellular receptors cellular signaling pathway Community coronavirus CoV COVID-19 Deleterious dendritic cell downregulating downregulation DPP4 Epidemics event Exacerbation Factor furin glycoprotein H1N1 Haemagglutinin Health Host IL-8 infected patients Inflammation initial initial viral load Innate innate immune response innate immune responses involved Ligand ligands Like lung lung innate immunity Macrophage middle multiple organ failure outbreak pandemic Pandemics pro-inflammatory mediator promoted protease Proteases Protein Resolution respiratory RNA genome SARS-CoV SARS-CoV-2 serine 2 single-stranded survival syndrome T-cell TLR TMPRSS2 transmembrane serine protease triggering trimeric spike TTSP type I type III virus virus entry [DOI] 10.3389/fimmu.2020.01229 PMC 바로가기 [Article Type] Immunology
COVID-19 in breast cancer patients: a cohort at the Institut Curie hospitals in the Paris areaResearch Article Published on 2020-05-282022-10-27 Journal: Breast Cancer Research : BCR [Category] COVID-19, [키워드] Abnormalities Admission age Analysis anti-cancer treatment association Breast cancer breast cancer patient breast cancer patients Characteristics clinical feature Cohort common Comorbidities Comorbidity Corticosteroid cough COVID-19 COVID-19 complication COVID-19 infection COVID-19 mortality COVID-19 patient COVID-19 symptoms cured Curie death deaths defined diagnosed with COVID-19 Diagnosis died Factor Fever France ground-glass opacity higher risk hospital Hospitalized hypertension ICH intensive care lung CT scan lung lesions outcome Paris Patient positive radiation therapy radiologic radiological features reported Result risk RNA SARS-CoV-2 severe COVID-19 survival Symptom transferred treated Treatment Univariate analysis Viral RNA was done with COVID-19 [DOI] 10.1186/s13058-020-01293-8 PMC 바로가기 [Article Type] Research Article
COVID-19 in breast cancer patients: a cohort at the Institut Curie hospitals in the Paris areaResearch Article Published on 2020-05-282022-10-27 Journal: Breast Cancer Research : BCR [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] Abnormalities Admission age Analysis anti-cancer treatment association Breast cancer breast cancer patient breast cancer patients Characteristics clinical feature Cohort common Comorbidities Comorbidity Corticosteroid cough COVID-19 COVID-19 complication COVID-19 infection COVID-19 mortality COVID-19 patient COVID-19 symptoms cured Curie death deaths defined diagnosed with COVID-19 Diagnosis died Factor Fever France ground-glass opacity higher risk hospital Hospitalized hypertension ICH intensive care lung CT scan lung lesions outcome Paris Patient positive radiation therapy radiologic radiological features reported Result risk RNA SARS-CoV-2 severe COVID-19 survival Symptom transferred treated Treatment Univariate analysis Viral RNA was done with COVID-19 [DOI] 10.1186/s13058-020-01293-8 PMC 바로가기 [Article Type] Research Article
Can Stem Cells Beat COVID-19: Advancing Stem Cells and Extracellular Vesicles Toward Mainstream Medicine for Lung Injuries Associated With SARS-CoV-2 InfectionsBioengineering and Biotechnology Published on 2020-05-262022-10-31 Journal: Frontiers in Bioengineering and Biotechnology [Category] COVID-19, [키워드] Administered Advancing anti-inflammatory agents Anti-viral attenuate Beat Can caused clinical trial clinical utility Combination coronavirus (2019-nCoV) COVID-19 COVID-19 disease curative Cytokine storm disease EVs Exosome extracellular vesicle Extracellular vesicles immunomodulatory IMPROVE Inflammation intravenously investigated lung damage lung injuries mainstream majority mechanism Medicine MSC MSCs outcome Patient people with COVID-19 pharmacological treatments regenerative properties reported risk SARS-CoV-2 SARS-CoV-2 virus secreted STEM stem cell Stem cell therapy survival therapeutic agents therapeutic effect therapeutic potential therapeutic strategy Therapies therapy Treatment treatment for COVID-19 Trial while [DOI] 10.3389/fbioe.2020.00554 PMC 바로가기 [Article Type] Bioengineering and Biotechnology
Disability progression among leprosy patients released from treatment: a survival analysis치료를 받은 나병 환자의 장애 진행: 생존 분석Research Article Published on 2020-05-242024-08-01 Journal: Infectious Diseases of Poverty [Category] 한센병, [키워드] cure leprosy Physical disability progression survival [DOI] 10.1186/s40249-020-00669-4 PMC 바로가기 [Article Type] Research Article