A three-arm, multicenter, open-label randomized controlled trial of hydroxychloroquine and low-dose prednisone to treat recurrent pregnancy loss in women with undifferentiated connective tissue diseases: protocol for the Immunosuppressant regimens for LIving FEtuses (ILIFE) trial미분화 결합 조직 질환이 있는 여성의 반복적인 임신 상실을 치료하기 위한 하이드록시클로로퀸 및 저용량 프레드니손의 3군, 다기관, 공개 라벨 무작위 대조 시험: LIFE(LIFE) 시험을 위한 면역억제 요법에 대한 프로토콜Study Protocol Published on 2020-09-092022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] abortion Activation addition Anticoagulant anticoagulation Arm assigned connective tissue connective tissue disease Controlled trial defined disease Efficacy eligible patient evaluate Evidence HCQ Hydroxychloroquine immune Immunosuppressant include induce Inflammation live births low-dose morbidities multicenter Open-label open-label randomized controlled trial outcome Patient patients placental Prednisone Pregnancy Prevent Primary outcome Prognosis progression protocol Randomized controlled trial Randomly Recurrent pregnancy loss Recurrent spontaneous abortion regimen secondary Secondary outcomes spontaneous abortion treat Trial Trial registration Undifferentiated Undifferentiated connective tissue disease Vascular damage women [DOI] 10.1186/s13063-020-04716-1 PMC 바로가기 [Article Type] Study Protocol
Anticoagulation in critically ill patients on mechanical ventilation suffering from COVID-19 disease, The ANTI-CO trial: A structured summary of a study protocol for a randomised controlled trialCOVID-19 질병으로 고통받는 중환자의 기계적 환기에 대한 항응고, The ANTI-CO 시험: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-09-072022-08-13 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 Abnormalities Administered allergic Anti-Co trial Anticoagulant anticoagulation anticoagulation treatment approval aPTT assumed attending physicians bivalirudin blinded Blinding Clinical improvement Coagulation comparator control group Controlled trial Corporation COVID-19 COVID-19 disease Critically ill patient D-dimer D-dimers dissemination distress dose dropout drug element eligibility eligible exclusion criteria expected experimental group FiO2 for inclusion groups heparin ICU IMPROVE include Inclusion inclusion criteria intervention group intravenously Invasive mechanical ventilation limit Local mechanical ventilation normally distributed number objective on mechanical ventilation outcome P/F P/F ratio PaO2 paO2/fiO2 parallel group parameter participant Patient patients patients with COVID-19 performed Physicians positive power power of 80% Pregnancy Primary outcome protocol randomised randomised controlled trial randomization Randomized receive recruitment Registered registration number respiratory distress Respiratory failure Sample size sample size calculation screened standard treatment status study drug Study protocol subcutaneously subject Taking the mean the patient thrombosis title treated Treatment treatment group Trial registration website [DOI] 10.1186/s13063-020-04689-1 PMC 바로가기 [Article Type] Letter
The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal–fetal transmission: a systematic review and meta-analysisReview Published on 2020-09-042022-10-31 Journal: European Journal of Medical Research [Category] COVID-19, SARS, [키워드] admitted to ICU Affect alteration analyzed angiotensin-converting enzyme-2 article Bilateral C-reactive protein Care cells Clinical course clinical feature clinical manifestations clinical symptom Cochrane Library Complication conducted coronavirus Coronavirus infection cough CoV COVID-19 death demonstrated diagnosed died distress fetal Fever General population gestation Google Scholar gravid greater ground-glass opacity growth Health Hydroxychloroquine Immunocompromised increased risk Infection Infectious disease Laboratory low expression Lung volume lymphocytopenia membrane MERS-CoV Meta-analysis Middle East respiratory syndrome mother myalgia Neonatal Neonate Non-COVID-19 Novel coronavirus-2019 occurred outcome outcomes Oxygen therapy Patient physiological change Pneumonia Pregnancy pregnant pregnant women Premature Preterm birth Prevalence ranged reported respiratory Result ribavirin risk rupture SARS-CoV SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus-2 study period systematic review Transmission Treatment vertical transmission Web of Science [DOI] 10.1186/s40001-020-00439-w PMC 바로가기 [Article Type] Review
Complicated COVID-19 in pregnancy: a case report with severe liver and coagulation dysfunction promptly improved by deliveryCase Report Published on 2020-09-042022-10-28 Journal: BMC Pregnancy and Childbirth [Category] COVID-19, SARS, [키워드] abdominal pain acute respiratory syndrome Atypical Caesarean section Case report case sery change Coagulation coagulation dysfunction coagulation impairment coronavirus Course COVID-19 COVID-19 infection differential diagnosis dry cough Evidence exacerbated exaggerate Fever HELLP syndrome high risk immune response Infection liver morbidity Mortality myalgia Nasopharyngeal swab nausea Neonate Obstetric management outcome pandemic Platelet count positive Pregnancy pregnant women raise Respiratory distress syndrome Respiratory failure returned risk SARS-CoV-2 Sepsis Shortness of breath suggested susceptibility the patient Transmission virus was performed women worsened [DOI] 10.1186/s12884-020-03172-8 PMC 바로가기 [Article Type] Case Report
How to perform and interpret the lung ultrasound by the obstetricians in pregnant women during the SARS-CoV-2 pandemicClinical Investigation Published on 2020-09-022022-10-28 Journal: Turkish Journal of Obstetrics and Gynecology [Category] COVID-19, [키워드] 24 hour Admission anatomical contribute Coronavirus 2019 Coronavirus-2 Course COVID-19 described diagnosed feasible indicated Interpretation limitation lung Lung ultrasound material pandemic pathologic Patient Pneumonia Pregnancy pregnant women provided respiratory Safe SARS-CoV-2 syndrome the SARS-CoV-2 was performed [DOI] 10.4274/tjod.galenos.2020.93902 PMC 바로가기 [Article Type] Clinical Investigation
Pregnancy worsens the morbidity of COVID-19 and this effect becomes more prominent as pregnancy advancesClinical Investigation Published on 2020-09-022022-10-28 Journal: Turkish Journal of Obstetrics and Gynecology [Category] COVID-19, [키워드] 95% confidence interval Admission affected Clinical characteristics Clinical severity co-morbidities Coronavirus 2019 Coronavirus-2 COVID-19 disease Fever gestation hospitals Infection intensive care intensive care unit admission material morbidity mortality rate need for oxygen outcome oxygen support Pregnancy pregnant pregnant patient pregnant women Preterm birth Rate respiratory risk SARS-CoV-2 significantly significantly more subject Support syndrome Tachycardia tachypnea tertiary care center vaginal delivery women [DOI] 10.4274/tjod.galenos.2020.38924 PMC 바로가기 [Article Type] Clinical Investigation
Anxiety levels and obsessive compulsion symptoms of pregnant women during the COVID-19 pandemicClinical Investigation Published on 2020-09-022022-10-28 Journal: Turkish Journal of Obstetrics and Gynecology [Category] COVID-19, [키워드] age Anxiety anxiety level can be used case-control study conducted Coronavirus-2 COVID-19 COVID-19 pandemic identify IMPROVE incidence material Mental mental health non-pregnant population nonpregnant obsessive-compulsion Obsessive-compulsive symptom outcome measures pandemic Pregnancy pregnant pregnant women Primary outcome questionnaire respiratory SARS-CoV-2 SARS-CoV-2 pandemic STAI state Symptom syndrome the SARS-CoV-2 total score Turkey two group women [DOI] 10.4274/tjod.galenos.2020.91455 PMC 바로가기 [Article Type] Clinical Investigation
[How well is the screening of pregnant women for HIV, syphilis, and hepatitis B implemented in Germany? An analysis based on routine data]Article Published on 2020-09-012023-06-12 Journal: Bundesgesundheitsblatt, Gesundheitsforschung, Gesu [Category] B형 간염, [키워드] health data Infectious diseases Laboratory tests Pregnancy [DOI] 10.1007/s00103-020-03199-4
Under the epidemic situation of COVID-19, should special attention to pregnant women be given?Article Published on 2020-09-012023-06-20 Journal: Journal of medical virology [Category] Fulltext, MERS, [키워드] COVID-19 Novel coronavirus Policy Pregnancy [DOI] 10.1002/jmv.25771 PMC 바로가기
Scrub Typhus Leading to Acute Liver Failure in a Pregnant PatientArticle Published on 2020-09-012023-08-30 Journal: Cureus [Category] E형 간염, [키워드] acute liver failure fetal loss Fulminant liver failure Multiorgan dysfunction Orientia tsutsugamushi outcome Pregnancy Rickettsia scrub typhus Trombiculid [DOI] 10.7759/cureus.10191 PMC 바로가기