Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2015–2016Article Published on 2017-10-012023-05-22 Journal: Antiviral Research [Category] Fulltext, 신종인플루엔자, [키워드] inhibitor markers neuraminidase resistance Surveillance susceptibility [DOI] 10.1016/j.antiviral.2017.08.004 PMC 바로가기 [Article Type] Article
Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2012: General view of the pathogens’ antibacterial susceptibilityarticle Published on 2017-09-302024-09-01 Journal: Journal of Infection and Chemotherapy [Category] 폐렴구균 감염증, [키워드] resistance respiratory tract infection Surveillance susceptibility [Article Type] article
High rate of adaptation of mammalian proteins that interact with Plasmodium and related parasitesPlasmodium 및 관련 기생충과 상호 작용하는 포유류 단백질의 높은 적응률Research Article Published on 2017-09-282022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adaptation adaptive allele ancestor Bacterial infections Blood blood cell caused cell membrane cell protein conserved controls Critical critical organ curated disease domain domains driven by elevated Evidence Evolution expected explained expression Genetic genetic resistance genomes group Host host adaptation host gene host protein host proteins hosts Human genome human populations humans identify illness immune immune function infect Infection Infectious disease Interaction involved lack life cycle liver malaria mammal mammalian mammalian protein mammals many cases matched control matched controls non-immune organ outcome over parasite parasites pathogen Pathogens Plasmodium Plasmodium falciparum Pleiotropy Protein Proteins red blood cell relative representing second selective significantly spectrin Substitution susceptibility terrestrial the strongest title variety Viral [DOI] 10.1371/journal.pgen.1007023 PMC 바로가기 [Article Type] Research Article
Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after InfectionArticle Published on 2017-08-222022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] administration alterations Altered Analysis Cardiovascular disorders clinical Clinical treatment Diseases Effect examination finding Glucose Health healthy controls High-dose indicated Infection infections information investigated Lipid lung metabolism metabolome metabolomic Methylprednisolone Pathologies Patient provided pulse questionnaire recovered recruited response SARS patient SARS patients SARS-CoV SARS-like coronavirus serum severe pneumonia significant difference suggested Survivors susceptibility systemic damage the patient treated tumors Year [DOI] 10.1038/s41598-017-09536-z PMC 바로가기 [Article Type] Article
Crosstalk between the tricarboxylic acid cycle and peptidoglycan synthesis in Caulobacter crescentus through the homeostatic control of α-ketoglutarateα-케토글루타레이트의 항상성 조절을 통한 Caulobacter crescentus의 트리카르복실산 회로와 펩티도글리칸 합성 간의 누화Research Article Published on 2017-08-212022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accumulation addition Alter Antibiotics approach approaches Bacteria bacterial cell bacterial cells biosynthetic block blocks building by-product Caulobacter crescentus caused Cell cell wall cell wall synthesis cellular cellular metabolism cellular processe cellular processes central metabolism characterized classical conserved CRISPRi Crosstalk deletion mutant Disruption drug design energy generate genetics growth highlight homeostasis homeostatic inhibit interfere Interference master regulator metabolism metabolite metabolomics Morphological morphology mutant peptidoglycan phenotype precursors property Replication required resulting reveal robust susceptibility susceptible synthesis TCA cycle the cell transcriptomics tricarboxylic acid while [DOI] 10.1371/journal.pgen.1006978 PMC 바로가기 [Article Type] Research Article
Deciphering the genetic control of gene expression following Mycobacterium leprae antigen stimulationMycobacterium leprae 항원 자극 후 유전자 발현의 유전자 제어 해독Research Article Published on 2017-08-092022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 한센병, [키워드] activated Affect Antigen bacterium binding site Blood cells caused conducted criteria Differential gene expression disease disease control displaying enrichment eQTL Evidence exposure to expression FDR Gene Expression gene expression level Genetic genetic control Genetic variation Genetic variations genomic highlight Host host genetics host response host responses human host human infectious disease immune Immune cell immune cells Infection Infectious disease Interaction involved knowledge leprosy loci mechanism modulate modulation Mycobacterium leprae natural selection nucleotide outlined pathogen Pathogenesis pathogenicity Patient performed Positive selection proportion Quantitative reaction Regulatory reported Seven significantly Single nucleotide polymorphism single nucleotide polymorphisms SNPs Stimulation suggested susceptibility the disease transcript transcription factor transcription factors transcriptional response triggered upregulation variant variants Variation while whole blood cell whole blood cells [DOI] 10.1371/journal.pgen.1006952 PMC 바로가기 [Article Type] Research Article
Association of the tandem polymorphisms (rs148314165, rs200820567) in TNFAIP3 with chronic hepatitis B virus infection in Chinese Han populationResearch Published on 2017-08-072023-06-02 Journal: Virology Journal [Category] B형 간염, [키워드] TNFAIP3 clinical disease Hepatitis B virus polymorphism susceptibility [DOI] 10.1186/s12985-017-0814-5 PMC 바로가기 [Article Type] Research
Is there a relationship between genetic factors and the incidence and severity of H1N1 in Kosova?: A preliminary investigation and pointers for further researchArticle Published on 2017-07-012023-06-24 Journal: Travel medicine and infectious disease [Category] 신종인플루엔자, [키워드] H1N1 Kosovo patients phenotype susceptibility [DOI] 10.1016/j.tmaid.2017.03.005
Genomic introgression mapping of field-derived multiple-anthelmintic resistance in Teladorsagia circumcinctaTeladorsagia circumcincta에서 필드 파생 다중 구충제 내성의 게놈 유전자 이입 매핑Research Article Published on 2017-06-232022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adopted affecting Analysis analyzed candidate gene changes in Chemotherapy complex contribute copy number drug resistance drugs eradication Evidence Evolution expression facilitated Factor framework Genes Genetic genetic architecture genetic background genetic factors Genotype humans identify increasingly lead livestock mechanism Multidrug resistance multidrug resistant multifactorial pair parasite parasites parasitic nematode parasitic nematodes pathogen performed polymorphism Population progeny prophylactic treatment Putative mechanisms Quantitative reduced Region regulatory region repeated resistance gene responsible sensitivity sheep single gene strain susceptibility susceptible Variation variety whole-genome widespread [DOI] 10.1371/journal.pgen.1006857 PMC 바로가기 [Article Type] Research Article
Allelic Variation in the Toll-Like Receptor Adaptor Protein Ticam2 Contributes to SARS-Coronavirus Pathogenesis in MiceMultiparental Populations Published on 2017-06-052022-10-31 Journal: G3 (Bethesda, Md.) [Category] Coronavirus, [키워드] adaptor affected chromosome collaborative cross contribute coronavirus correlated Critical disease driving early stage exhibiting F2 Factor Genetic Genetic variation hemorrhage highlight Host host susceptibility genes Infection loci locus mice mouse model MPP Multi-parent Advanced Generation Inter-Cross (MAGIC) multiparental populations Pathogenesis phenotype Phenotypes Protein pulmonary hemorrhage Quantitative respiratory responses responsible SARS-CoV SARS-CoV infection Strains susceptibility susceptible Ticam2 TLR signaling pathways Viral load viral titer virus titer weight weight loss [DOI] 10.1534/g3.117.041434 PMC 바로가기 [Article Type] Multiparental Populations