The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells
Research Article
[키워드] A20
A549
activated
acute respiratory distress
adjust
approach
ARDS
attenuate
Cell
cells
cellular
change
characterized
chromatin
combinations
Complete
Concentration
contribute
coronavirus
coronavirus-infected cells
correlated
cytoplasm
cytoplasmic
de novo gene
Degradation
enhancer
enhancer region
Epigenetic
event
example
expected
expression
expression level
expression of gene
Factor
fine-tune
Gene Expression
Genes
genes encoding
Genome
genome-wide investigation
genomic region
HCoV-229E
HKU1
Host
host cell
host cell cytoplasm
host response
human coronavirus 229E
humans
identify
IKK
IKKβ
IL-1
immunomodulatory factor
immunomodulatory function
infected cell
infections
Inflammatory
Inflammatory cytokine
involved
IκBα
Lung disease
mechanism
mechanisms
MERS-CoV
metabolic processes
Modification
molecular
molecular basis
motif
NEMO
NF-κB
NF-κB signaling
NL63
nuclear
nuclear chromatin
nucleus
OC43
p65
pathogenic
Pathogens
pathology
promote
promoter
Protein
provide
recruited
recruitment
regulatory region
Replication
required
restrict
RNA Polymerase II
RNA virus
SARS-CoV
second
shown
Signaling
subunit
syndrome
These cells
TNFAIP3
transcribed
Transcription
transcription factor
Transcriptome
Treatment
Trigger
upper respiratory tract
upregulated gene
upregulation
variety
viral replication
virus
virus replication
Virus-host interactions
Zoonotic coronavirus
[DOI] 10.1371/journal.ppat.1006286 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.ppat.1006286 PMC 바로가기 [Article Type] Research Article