functional – Page 156 – Communicable Diseases Research

Investigating Ketone Bodies as Immunometabolic Countermeasures against Respiratory Viral Infections

Perspective

Published on 2020-07-152022-11-01
Journal: Med (New York, N.Y.) [Category] COVID-19, MERS, SARS,

Functional and cognitive outcomes after COVID-19 delirium

Brief Report

Published on 2020-07-142022-10-31
Journal: European Geriatric Medicine [Category] Coronavirus, MERS, SARS,

Emergency Care Systems: The Missing Link for Effective Treatment of COVID-19 in Africa

응급 치료 시스템: 아프리카에서 COVID-19의 효과적인 치료를 위한 누락된 링크

Letter to the Editor

Published on 2020-07-142022-09-12
Journal: Disaster Medicine and Public Health Preparedness [Category] MERS, 진단,

[키워드] African Care COVID-19 COVID-19 patients Critical death disease disease outbreaks Emergency emergency medicine emergency service Epidemic functional Health health system health systems hospital missing rising
[DOI] 10.1017/dmp.2020.239 PMC 바로가기 [Article Type] Letter to the Editor

Smoking increases the risk of infectious diseases: A narrative review

Review Paper

Published on 2020-07-142022-10-28
Journal: Tobacco Induced Diseases [Category] COVID-19,

High Throughput Virtual Screening to Discover Inhibitors of the Main Protease of the Coronavirus SARS-CoV-2

Article

Published on 2020-07-132022-10-30
Journal: Molecules [Category] COVID-19, SARS,

[키워드] 3CL pro acute respiratory syndrome amino acid residues approved drugs bind binding catalytic dyad characterized Compound compounds computer-aided drug design coronavirus COVID-19 demonstrated docking Drug repurposing drugs enzyme functional group Hormones Hydrogen bond identify in silico drug design in vitro include inhibitor inhibitors inhibitors of SARS-CoV-2 inhibitory activity Ligand monocyclic natural products protease protocol Replication reported residue SARS-CoV virus SARS-CoV-2 Screening severity of COVID-19 starting point the SARS-CoV-2 throughput tyrosine kinase inhibitors viral replication inhibition
[DOI] 10.3390/molecules25143193 PMC 바로가기 [Article Type] Article

TWIRLS , a knowledge‐mining technology, suggests a possible mechanism for the pathological changes in the human host after coronavirus infection via ACE2

Research Article

Published on 2020-07-132022-10-31
Journal: Drug development research [Category] COVID-19,

[키워드] ACE2 acute lung injury Analysis analyzed Angiotensin II approach ARB article automatically binding blockers Blood build caused changes in coronavirus Coronavirus infection COVID‐19 patient cytokine Cytokine storm effective Efficiency enzyme Epidemic functional had more help homeostasis Host hosts human host hypertension independent Infection information involved knowledge leukemia Literature mining Liver cancer Lower mechanism pathological change Perspective problems processed public health emergency receptor Regulation Regulatory renin‐angiotensin system researcher subject Symptom System topic inference treat triggering virus
[DOI] 10.1002/ddr.21717 PMC 바로가기 [Article Type] Research Article

The Potential Effect of Novel Coronavirus SARS-CoV-2 on NK Cells; A Perspective on Potential Therapeutic Interventions

Immunology

Published on 2020-07-102022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS,

Epigenetic Regulator miRNA Pattern Differences Among SARS-CoV, SARS-CoV-2, and SARS-CoV-2 World-Wide Isolates Delineated the Mystery Behind the Epic Pathogenicity and Distinct Clinical Characteristics of Pandemic COVID-19

SARS-CoV, SARS-CoV-2 및 SARS-CoV-2 전 세계 분리주 사이의 후성유전 조절자 miRNA 패턴 차이로 팬데믹 COVID-19의 서사적 병원성과 독특한 임상적 특징 뒤에 숨겨진 미스터리

Genetics

Published on 2020-07-102022-08-13
Journal: Frontiers in Genetics [Category] 유전자 메커니즘,

[키워드] alleviate anomalies Anomaly antiviral miRNAs autophagy binding breathing complications cardiovascular diseases cellular miRNA cellular pathway clinical Comorbidities Complication computational approach Computational approaches country COVID-19 COVID-19 patients death death rates diabetes difference disease effective epigenetic modulator epigenetic regulator experiments Factors functional Gene Expression Host host antiviral miRNA host genes host immunity host miRNA host's miRNAs human cell IFN-I IFN-I signaling immune regulation immune-escape mechanism immune-signaling pathways implication isolate latency lead Microarray miRNA miRNA clusters miRNA-mediated interaction miRNA-microRNA miRNAs mode modulate molecular mechanism Neutralizing normalized over representation analysis Pathogenesis Pathways patients with comorbidity pattern predict predicted profile regulator RNA therapeutics RNA-Seq SARS virus SARS viruses SARS-CoV SARS-CoV and SARS-CoV-2 viral miRNAs SARS-CoV and SARS-CoV-2 viruses SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 miRNAs SARS-CoV-2 pathogenesis SARS-CoV-2 viral SARS-CoV-2 virus SARS-infected human cell microarray signaling pathways Support symptoms of COVID-19 target targets the SARS-CoV-2 Viral viral miRNA viral miRNAs viral pathogenesis viruses
[DOI] 10.3389/fgene.2020.00765 PMC 바로가기 [Article Type] Genetics

Adaptive immunity to SARS-CoV-2

Review Article

Published on 2020-07-092022-10-29
Journal: Oxford Open Immunology [Category] COVID-19,

[키워드] absence Activation acute infection acute respiratory syndrome Adaptive immunity antibody Antibody Response Antibody titre blood vessels CD4 CD8 Clinical use common cold coronavirus Correlate of protection Course COVID-19 cross-reactivity Cytokines detectable disease disease severity duration of exposure epitope Evidence expression full recovery functional human coronavirus human coronaviruses Hyperinflammatory IL-6 immune memory immunogenic immunology immunopathological immunopathology individual Infection kidney lung majority mechanism neutralizing antibody neutralizing monoclonal antibody offer Pathogenesis Protective question raised rapid progress response SARS-CoV-2 serum biomarker severe cases susceptibility symptomatic disease Symptoms T cell T-cell T-cell immunity therapeutic target tissue damage Vaccine viral antigens Viral load Virus neutralization while
[DOI] 10.1093/oxfimm/iqaa003 PMC 바로가기 [Article Type] Review Article

Development and Clinical Evaluation of a Web-Based Upper Limb Home Rehabilitation System Using a Smartwatch and Machine Learning Model for Chronic Stroke Survivors: Prospective Comparative Study

스마트워치와 머신러닝 모델을 이용한 만성 뇌졸중 생존자를 위한 웹 기반 상지 재활 시스템 개발 및 임상 평가: 전향적 비교 연구

Original Paper

Published on 2020-07-092022-08-13
Journal: JMIR mHealth and uHealth [Category] 임상,

[키워드] accelerometer Accuracy activity Algorithm artificial intelligence assessment Beck Care chronic chronic stroke clinical clinical evaluation clinical outcomes Clinical research clinical study Comparative conducted control group Convolutional neural network COVID-19 pandemic data set data sets determine develop development drop Efficacy enrolled evaluate extremity facilitate feasibility flexion Follow-up Frequency function functional group Gyroscope Health care health care systems home home care home-based rehabilitation IMPROVE internal rotation inventory joint machine learning ML model Model motor Motor Function objective participant Participation Patient performed physical Physical therapy Prospective range of motion recent recognize Registration rehabilitation rehabilitation exercises Research Result ROM service shoulder joint shown Smartphone smartwatch statistical analysis stroke survivor Survivors System Test the mean therapy Treatment two group two groups upper Upper extremity user was used wearable device wearable technology Wolf
[DOI] 10.2196/17216 PMC 바로가기 [Article Type] Original Paper