The effect of prostacyclin (Iloprost) infusion at a dose of 1 ng/kg/min for 72 hours compared to placebo in mechanically ventilated patients with COVID-19: A structured summary of a study protocol for a randomized controlled trial인공호흡기를 사용하는 COVID-19 환자에서 위약과 비교하여 72시간 동안 1ng/kg/min 용량의 프로스타사이클린(일로프로스트) 주입 효과: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-08-262022-08-13 Journal: Trials [Category] MERS, 임상, [키워드] (Iloprost (normal saline) 1:1 Acute coronary syndrome Adult patient Adult patients age anticipated Biomarker bleeding blinded Blinding block can not Capital Capital Region capture Clinicians comparator concealed conducted Confirmed Confirmed COVID-19 infection Consent coronary syndrome COVID-19 COVID-19 infection COVID-19 patients criteria Day defined Denmark dissemination dose element endothelial endotheliopathy EudraCT exclusion criteria exploratory facilitate FIVE heart failure Hvidovre Hospital hypersensitivity Iloprost intensive care unit intensive care units investigators Local mechanical ventilation mechanically ventilated mechanically ventilated COVID-19 patients mechanically ventilated patient multicenter normal saline number objective outcome parallel group participant Patient patients performed Placebo Pregnancy primary endpoint prostacyclin protocol randomisation randomised Randomized Randomized controlled trial recruitment REDCap Region Sample size sequence statisticians status stratified Study protocol Suspected thrombomodulin total sample size Trial Urine website Withdrawal [DOI] 10.1186/s13063-020-04696-2 PMC 바로가기 [Article Type] Letter
COVID-19 Barriers to Care for Pregnant Patients in Prolonged IsolationCase Report Published on 2020-08-252022-10-31 Journal: Case Reports in Obstetrics and Gynecology [Category] COVID-19, [키워드] acute respiratory syndrome Asymptomatic barrier Care Contact coronavirus coronavirus disease COVID-19 gestation Haiti Healthcare system healthcare worker highlight Isolation membrane patients Personal protective equipment populations positive PPE Precaution Pregnancy pregnant population pregnant women Premature Prevent Prolonged question remained responsible risk rupture SARS-CoV-2 SARS-CoV-2 testing Transmission unique [DOI] 10.1155/2020/8847859 PMC 바로가기 [Article Type] Case Report
Clinical Characteristics and Outcomes of Childbearing-Age Women With COVID-19 in Wuhan: Retrospective, Single-Center StudyOriginal Paper Published on 2020-08-242022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, [키워드] acute respiratory syndrome adverse outcomes affected alkaline phosphatase antibiotic Antiviral Atypical bleeding both groups caused childbearing age clinical Clinical characteristics collected Concentration coronavirus coronavirus disease cough COVID-19 D-dimer Diagnosis died discharge elevated epidemiological Epidemiology erythrocyte sedimentation rate evaluate fetal group health information High-sensitivity C-reactive protein hospital influenza A virus Laboratory laboratory feature laboratory-confirmed lactate dehydrogenase lymphocyte majority management median age Mild moderate MOST neutrophil nonpregnant objective outbreak outcome outcomes Pain Patient patients positive Pregnancy pregnant pregnant patient pregnant patients pregnant women previous study proportion reduced Result SARS-CoV-2 severe pneumonia significantly higher Spread Symptom tested therapy Tongji Hospital two groups with COVID-19 women Wuhan Wuhan, China [DOI] 10.2196/19642 PMC 바로가기 [Article Type] Original Paper
Intraoperative coagulopathy during cesarean section as an unsuspected initial presentation of COVID-19: a case reportCase Report Published on 2020-08-242022-10-28 Journal: BMC Pregnancy and Childbirth [Category] COVID-19, MERS, [키워드] association Asymptomatic asymptomatic patient bleeding Case report Cesarean section clinical picture Coagulopathy concerning contribute COVID COVID-19 D-dimer disease Effect Elevation Evidence expected fibrinogen help higher risk identify infected with SARS-CoV-2 initial International intraoperative Laboratory Laboratory tests normalized Patient Platelets Pregnancy pregnant pregnant population Prothrombin time SARS-CoV-2 SARS-COV-2 infection Scientific community significantly more the patient unique [DOI] 10.1186/s12884-020-03140-2 PMC 바로가기 [Article Type] Case Report
Psychological responses and lifestyle changes among pregnant women with respect to the early stages of COVID-19 pandemicOriginal Articles Published on 2020-08-202022-10-30 Journal: The International Journal of Social Psychiatry [Category] COVID-19, MERS, [키워드] age association caused change China Chinese conducted COVID-19 COVID-19 pandemic early stage group Health highest ies Impact investigated measure Mental mental health mental health issues populations Pregnancy pregnant women Psychological psychological Impact psychological response question questionnaire reported scale Sociodemographic Stress women [DOI] 10.1177/0020764020952116 PMC 바로가기 [Article Type] Original Articles
Host-pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategiesReview Published on 2020-08-192023-06-14 Journal: Immunobiology [Category] MERS, SARS, [키워드] anti-virals co-morbidities COVID-19 Life-cycle pathophysiology Pregnancy SARS-CoV-2 Vaccine [DOI] 10.1016/j.imbio.2020.152008 PMC 바로가기 [Article Type] Review
Single-Cell RNA-seq Identifies Cell Subsets in Human Placenta That Highly Expresses Factors Driving Pathogenesis of SARS-CoV-2Cell and Developmental Biology Published on 2020-08-192022-10-31 Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19, [키워드] abundantly expressed ACE2 addition ANPEP binding carried Cell cells cellular co-expressed Complication component coronavirus Coronaviruses COVID-19 CTSB CTSL DPP4 during pregnancy Express expressed Factor Glucose healthy host cells Human identify in viral infected with SARS-CoV-2 Infection Inflammation involved JAK-STAT pathway marker membranes mitochondrial metabolism mother mRNA Neonate novel coronavirus disease Other other protease pathogen pathway physically Placenta placental positive predict Pregnancy pregnant women Premature priming proportion protease TMPRSS2 Proteases PROTECT Protein receptor receptor ACE2 receptors Replication required respiratory RNA-Seq rupture SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection shown single-cell RNA-seq subset subtype systematic review target the S protein these cell TMPRSS2 Transport trophoblast unique viral S protein Viremia virus were also expressed with COVID-19 [DOI] 10.3389/fcell.2020.00783 PMC 바로가기 [Article Type] Cell and Developmental Biology
Hepatitis B-related hepatocellular carcinoma in a 36-year-old pregnant woman: prognosis and management dilemmaCase Report Published on 2020-08-182023-06-02 Journal: The Pan African Medical Journal [Category] B형 간염, [키워드] Chronic hepatitis B infection Hepatocellular carcinoma Pregnancy [DOI] 10.11604/pamj.2020.36.298.22658 PMC 바로가기 [Article Type] Case Report
MS, pregnancy and COVID-19Topical Review Published on 2020-08-172022-10-30 Journal: Multiple sclerosis (Houndmills, Basingstoke, Engla [Category] COVID-19, MERS, SARS, [키워드] antenatal care Autoimmune disease available data Clinical management concern COVID-19 Evidence include individuals Infection infections information Interaction multiple sclerosis Novel coronavirus novel coronavirus SARS-CoV-2 Obstetric pandemic Pregnancy Pregnant woman pregnant women provide SARS-CoV-2 women [DOI] 10.1177/1352458520949152 PMC 바로가기 [Article Type] Topical Review
Analysis of the Impact of the Confinement Resulting from COVID-19 on the Lifestyle and Psychological Wellbeing of Spanish Pregnant Women: An Internet-Based Cross-Sectional SurveyArticle Published on 2020-08-152022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] collected conducted COVID-19 cross-sectional survey Impact information lifestyle no significant difference occur Pandemics participated physical physical activity Pregnancy pregnant women promote Quality of life quarantine reduce significant decrease Spanish Stress survey women [DOI] 10.3390/ijerph17165933 PMC 바로가기 [Article Type] Article