Predictors of mortality in patients under treatment for chronic hepatitis B in Ethiopia: a prospective cohort studyResearch Article Published on 2019-05-152023-05-23 Journal: BMC Gastroenterology [Category] B형 간염, Fulltext, [키워드] antiviral therapy Epidemiology hepatitis B resource-limited settings survival [DOI] 10.1186/s12876-019-0993-1 PMC 바로가기 [Article Type] Research Article
Stage of Gestation at Porcine Epidemic Diarrhea Virus Infection of Pregnant Swine Impacts Maternal Immunity and Lactogenic Immune Protection of Neonatal Suckling PigletsImmunology Published on 2019-04-242022-11-01 Journal: Frontiers in Immunology [Category] Coronavirus, MERS, [키워드] acute diarrhea Affect affected antibody antibody secreting cell ASC B cells cause change circulating Control correlated Course Critical Cytokines determine during pregnancy epidemic diarrhea example gestation gut-mammary-secretory IgA axis IgA IgG immature immune system immune parameter immune protection immune response Immunity Impact implication Infection influence inoculated intestinal lactogenic Lactogenic immunity lymphocyte Maternal medium mucosal naïve Neonatal Neonate Neutralizing PEDV positively correlated Pregnancy pregnant protection required response resulting serum significantly significantly higher Stage stimulate stimulated subsequent Suckling survival survival rate swine three group Vaccines viral infections virulence virus [DOI] 10.3389/fimmu.2019.00727 PMC 바로가기 [Article Type] Immunology
Kctd9 Deficiency Impairs Natural Killer Cell Development and Effector FunctionImmunology Published on 2019-04-102022-11-01 Journal: Frontiers in Immunology [Category] Coronavirus, MERS, [키워드] ameliorated caused CD11b Cell cytokine cytotoxicity deficiency degranulation development domain effector evidenced exhibited expressed expression fulminant hepatitis function granzyme B Hepatitis hepatitis B homologous identify IFN-γ Immune-mediated in vitro Infection investigated Kctd9 knockout mice Lineage liver Liver damage manifested maturation mechanism mice murine hepatitis virus natural natural killer NK cell NK cell function NK cells Patient phenotype potassium channel progression proliferative proportion reduction in Regulation selective supported survival transcription factors tumor cell wild-type [DOI] 10.3389/fimmu.2019.00744 PMC 바로가기 [Article Type] Immunology
Expression Analysis of Long Non-Coding RNA HAR1A and HAR1B in HBV-Induced Hepatocullular Carcinoma in Chinese PatientsArticle Published on 2019-04-082023-06-18 Journal: Laboratory medicine [Category] B형 간염, [키워드] expression HAR1A HAR1B Hepatocellular carcinoma RT-qPCR survival [DOI] 10.1093/labmed/lmy055
The N-Terminal Domain of Spike Protein Is Not the Enteric Tropism Determinant for Transmissible Gastroenteritis Virus in PigletsArticle Published on 2019-03-302022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] accelerate affected approach Bacterial Cas9 cDNA Cell chromosome Clinical sign clone coronavirus CRISPR/Cas9 demonstrated determinant enteric enteric tropism experiment full-length gastroenteritis genetics growth help Mortality mutant N-terminal domain PK-15 platform Protein rescued Research Respiratory Coronavirus reverse genetics spike spike gene Spike protein survival TGEV transmissible gastroenteritis virus tropism Vaccine virulence virus [DOI] 10.3390/v11040313 PMC 바로가기 [Article Type] Article
LncRNA CASC11 promotes cancer cell proliferation in hepatocellular carcinoma by inhibiting miRNA-188-5pArticle Published on 2019-03-252023-06-02 Journal: Bioscience Reports [Category] B형 간염, [키워드] Hepatocellular carcinoma lncRNA CASC11 miR-188-5p survival [DOI] 10.1042/BSR20190251 PMC 바로가기
Transmission of hepatitis E virus by water: An issue still pending in industrialized countriesReview Published on 2019-03-152023-06-11 Journal: Water research [Category] E형 간염, [키워드] Hepatitis E virus (HEV) Occurrence survival Transmission Variability water [DOI] 10.1016/j.watres.2018.12.014 [Article Type] Review
Interplay between mitochondria and diet mediates pathogen and stress resistance in Caenorhabditis elegans미토콘드리아와 식단 사이의 상호 작용은 Caenorhabditis elegans에서 병원체와 스트레스 저항을 매개합니다Research Article Published on 2019-03-132022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Adults Affect alleviation Amino acid amino acid metabolism Anemia arise B12 bacterial pathogen Bacterial pathogenesis Bacterial pathogens biochemical Caenorhabditis canonical clearance cofactor condition Critical Defense deficiency demonstrated diet E . coli elegan elegans excess exhibited exposure to Genetic Health homeostasis Host host defense improvement Improvements Increasing independent independent of Interaction intermediate knockdown Laboratory Loss metabolism methylmalonyl-CoA microbiota mitochondrial mitochondrial dysfunction neurological defects organism overexpression pathogen pathogenic Pathogens Pathways phenotype physiological propionate RNAi-mediated gene sensitivity Stress Support survival susceptibility variety vitamin B12 vitamin B12 deficiency were used worm worms [DOI] 10.1371/journal.pgen.1008011 PMC 바로가기 [Article Type] Research Article
Heme peroxidase HPX-2 protects Caenorhabditis elegans from pathogensHeme peroxidase HPX-2는 Caenorhabditis elegans를 병원체로부터 보호합니다Research Article Published on 2019-01-292022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] addition Author Caenorhabditis elegan Caenorhabditis elegans catalytic cause changes in characterization complexity component conditions contribute Defense demonstrated Disruption DNA domain downstream elegan elegans ENCODE enzyme exhibited expression fluorescent function generate genes encoding greater heme Host host defense host tissue hydrogen hydrogen peroxide hypodermis indicated Infection Infectious disease Infectious diseases information Innate immunity intestinal involved labeling limit mammalian mechanism microbe microbial microbial infection morbidity morbidity and mortality Morphological mutant NADPH NADPH oxidase observation organ oxygen pathogen pathogenic Pathogens pathway peroxidase peroxidases pharynx previous study PROTECT Protective Reactions reactive oxygen species regulated required residue RNA interference RNA-seq analysis RNAi ROS ROS production shown survival therapy tissue worm [DOI] 10.1371/journal.pgen.1007944 PMC 바로가기 [Article Type] Research Article
Apatinib for Patients With Sorafenib-Refractory Advanced Hepatitis B Virus Related Hepatocellular Carcinoma: Results of a Pilot StudyArticle Published on 2019-01-012023-06-16 Journal: Cancer control : journal of the Moffitt Cancer Cen [Category] B형 간염, [키워드] apatinib Hepatocellular carcinoma refractory sorafenib survival [DOI] 10.1177/1073274819872216 PMC 바로가기