Specific changes of erythroid regulators and hepcidin in patients infected by SARS-COV-2Observational Study Published on 2022-04-012022-10-05 Journal: Journal of investigative medicine : the official p [Category] COVID19(2023년), SARS, 임상, [키워드] both groups C reactive protein change Concentration COVID-19 COVID19 defined described ERFE evaluate ferritin growth hematological parameters Inflammation inflammatory signal involved IQR iron iron homeostasis median metabolism Patient patients with COVID-19 performed plasma positive RT-PCR Protein receptor Regulatory SARS-CoV-2 SARS-COV-2 infection Sepsis single-center Specific statistically Transferrin [DOI] 10.1136/jim-2021-002270 PMC 바로가기 [Article Type] Observational Study
Cardiac And Inflammatory Biomarkers And New Or Worsening Heart Failure In High-risk Patients With COVID-19Conference abstract Published on 2022-04-012022-10-05 Journal: Journal of cardiac failure [Category] 바이오마커, [키워드] adverse outcome age association average baseline biochemical marker BNP C-reactive protein cardiac Cardiomyopathy cell activation clinical collected condition consequence coronary syndrome COVID-19 Cytokines decrease defined develop Diagnosis discharge dysfunction Ejection fraction elevated enrolled failure Follow-up greater groups heart Hospital admission Hospitalized hsCRP identify IL-6 Immune cell Inflammation Inflammatory biomarker inflammatory biomarkers Inflammatory marker interleukin-6 interquartile range IQR Ischemia male management measure mechanism median multifactorial myocardial injury myocarditis New no significant difference Patient peptide performed plasma pro-inflammatory cytokine storm profile prospective cohort study quantification reported Result risk factor sensitivity serum specimen Subtypes syndrome Trigger troponin levels ventricular with COVID-19 worsening [DOI] 10.1016/j.cardfail.2022.03.243 [Article Type] Conference abstract
Routine molecular point-of-care testing for SARS-CoV-2 reduces hospital-acquired COVID-19SARS-CoV-2에 대한 일상적인 분자 진료 현장 검사는 병원에서 획득한 COVID-19를 감소시킵니다.Article Published on 2022-04-012022-09-12 Journal: The Journal of Infection [Category] COVID19(2023년), SARS, 진단, [키워드] 95%CI Admission Cohort COVID-19 COVID-19 case COVID-19 positive patients evaluated Hospital acquired Hospital acquired infection Implementation study IMPROVE Infection IQR Laboratory Local molecular National NHS non-infected outcome measure Patient PCR POCT point-of-care point-of-care test point-of-care testing Primary outcome proportion reduce reduced routine SARS-CoV-2 secondary tested the median [DOI] 10.1016/j.jinf.2022.01.034 PMC 바로가기 [Article Type] Article
Prospective Validation of a Rapid Host Gene Expression Test to Discriminate Bacterial From Viral Respiratory Infection바이러스성 호흡기 감염에서 박테리아를 구별하기 위한 신속한 숙주 유전자 발현 검사의 전향적 검증Multicenter Study Published on 2022-04-012022-09-11 Journal: JAMA Network Open [Category] 유전자 메커니즘, 진단, [키워드] 95% CI absence acute COVID-19 acute respiratory illness age Analysis antibacterial therapy antibiotic ARI Asian Bacterial Bacterial infection black Care cause Characteristics children clinical clinically Cohort Concordance diagnostic Emergency Departments enrolled Enrollment entire cohort Ethnicity expression febrile female followed by group groups Hispanic Host host gene host gene expression host response IMPROVE individual IQR less likelihood male median age Messenger RNA multicenter Native Negative predictive value NPV offer outcome outcomes participant Participants pathogen Patient patients with ARI patients with COVID-19 performance Positive predictive value Predictive value primary analysis Probability procalcitonin Prospective quantified Rapid reported respiratory Respiratory illness resulting sensitivity specificity stratified Test the median validation Viral viral infection white with COVID-19 [DOI] 10.1001/jamanetworkopen.2022.7299 PMC 바로가기 [Article Type] Multicenter Study
Boosters reduce in-hospital mortality in patients with COVID-19: An observational cohort analysisResearch article Published on 2022-04-012022-10-05 Journal: The Lancet Regional Health - Americas [Category] 변종, [키워드] added adults hospitalized age agency baseline booster booster dose Care Characteristics Cohort cohort analysis COVID-19 death diagnosis of COVID-19 Effectiveness Endpoint female finding Follow-up funding group higher risk Hospitalization identify in-hospital mortality individual Infection intensive care IQR majority male median median age Mortality Most patient multicenter offer Older outcome Patient patients primary endpoint reduce required Research risk factor SARS-CoV-2 secondary severe illness severe SARS-CoV-2 Spread still hospitalized subpopulation Treatment Trial vaccination variable variant were excluded [DOI] 10.1016/j.lana.2022.100227 [Article Type] Research article
Immunogenicity and safety after the third dose of BNT162b2 anti-SARS-CoV-2 vaccine in patients with solid tumors on active treatment: a prospective cohort study활성 치료 중인 고형 종양 환자에서 BNT162b2 항-SARS-CoV-2 백신 3차 접종 후 면역원성과 안전성: 전향적 코호트 연구Article Published on 2022-04-012022-09-11 Journal: ESMO open [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] active treatment acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration anti-SARS-CoV-2 antibody baseline BNT162b2 BNT162b2 anti-SARS-CoV-2 vaccine booster booster dose Cancer cancer patient Cancer patients cell-mediated immune cell-mediated immune response Concentration consecutive patient coronavirus coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 infection Delta dose effective Efficacy enrolled evaluated Gamma humoral IgG IgG antibody immunogenicity Immunoglobulin Immunoglobulin G interferon interferon gamma interferon-γ interquartile range IQR median Messenger RNA naïve naïve subject naïve subjects neutralization Neutralizing neutralizing antibody of BNT162b2 omicron Patient patients Preliminary data primary endpoint prospective cohort study quantified reached recruited Release respiratory SARS-CoV-2 SARS-CoV-2 vaccine serum severe acute respiratory syndrome Coronavirus significantly higher solid cancer solid tumor subject subjects the median the SARS-CoV-2 third dose Treatment Trigger Vaccine variant variants variants of concern VOCs were used whole blood sample wild-type strain [DOI] 10.1016/j.esmoop.2022.100458 PMC 바로가기 [Article Type] Article
Improving vaccination coverage and offering vaccine to all school-age children allowed uninterrupted in-person schooling in King County, WA: Modeling analysisArticle Published on 2022-04-012022-11-16 Journal: Mathematical biosciences and engineering : MBE [Category] COVID19(2023년), SARS, 변종, [키워드] addition age age structured model Analysis analyzed benefit calibrated changes in children Coverage COVID-19 COVID-19 vaccination Critical dynamic Epidemic Epidemiology Health Hospitalization hospitalizations Improving Interaction IQR King limit mathematical mathematical modeling measure median modeling morbidity and mortality physical PPI predicted Prevent proportion provide Rapid reached reduce reducing reduction reported restored SARS-CoV-2 transmission SARS-CoV-2 variant School social distancing Social distancing measure Spread the epidemic trajectory USA vaccinate vaccination Vaccine variants of concern Washington [DOI] 10.3934/mbe.2022266 PMC 바로가기
Bacterial/fungal infection in hospitalized patients with COVID-19 in a tertiary hospital in the Community of Castilla y León, Spain스페인 카스티야 이 레온 지역 3차 병원에 입원한 COVID-19 환자의 박테리아/진균 감염Observational Study Published on 2022-04-012022-09-11 Journal: Enfermedades infecciosas y microbiologia clinica ( [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] Acinetobacter Acinetobacter baumannii Acinetobacter baumanniia Admission analyses Bacteremia Brote Coinfección Coinfection Comorbidities contribute contributed COVID-19 COVID-19 patients demographic determine diagnosed elevated English Factor hospital hospitalized patient hospitalized patients ICU ICU patient ICU Patients incidence increase Increases Infection intensive care unit interferon IQR Leukocytosis majority male median age men Mortality MOST multidrug-resistant multivariate logistic regression observational study outbreak pacientes hospitalizado pathogen Pathogens Patient patients Predictive predictor profile profiles pulmonary aspergillosis respiratory infections SARS-CoV-2 SARS-CoV-2 pneumonia Sobreinfección Spain Spanish Staphylococcus aureus Streptococcus pneumoniae superinfection Superinfections Tocilizumab urinary viral respiratory infection viral respiratory infections with COVID-19 [DOI] 10.1016/j.eimce.2022.02.002 PMC 바로가기 [Article Type] Observational Study
Serum zinc levels in pediatric patients with COVID-19Observational Study Published on 2022-04-012022-10-05 Journal: European journal of pediatrics [Category] COVID19(2023년), SARS, 임상, [키워드] Adults Analysis Antiviral effect association children conducted control group correlation COVID-19 Critical cut-off deficiency defined determine diagnosed with COVID-19 disease disease severity Factor growth Hospitalization hospitalizations Immunity incidence IQR living environment median median age neurologic participated Patient patients with COVID-19 Pediatric patient performed prospective observational study SARS-CoV-2 serum severity of COVID-19 Sex significantly higher significantly lower SPSS the median to define Variation window with COVID-19 Zinc [DOI] 10.1007/s00431-021-04348-w PMC 바로가기 [Article Type] Observational Study
Resuscitation with blood products in patients with trauma-related haemorrhagic shock receiving prehospital care (RePHILL): a multicentre, open-label, randomised, controlled, phase 3 trialClinical Trial Published on 2022-04-012022-10-05 Journal: The Lancet. Haematology [Category] Fulltext, MERS, 임상, [키워드] 1:1 absence acute respiratory distress adjusted adjusted relative risk Administered adverse event age assigned average benefit Blood blood product Care caused characteristics of patient clearance Complication concealed COVID-19 pandemic Critical care deaths defined eligibility Follow-up identify Injury intention-to-treat population intravenous investigated involved IQR Lactate Liver function male median median age Mortality multicentre nine occurred Open-label outcome parallel group participant participants randomly assigned Patient phase 3 trial plasma Primary outcome pulse randomisation randomised Randomly receive receiving recruitment red blood cell reducing mortality Registered remains uncertain required Research Resuscitation risk Sample size Serious Adverse Events severity Shock Sodium chloride stratified syndrome Systolic blood pressure time tissue trauma Treatment treatment group Trial were assessed [DOI] 10.1016/S2352-3026(22)00040-0 PMC 바로가기 [Article Type] Clinical Trial