Data-Driven Analysis of COVID-19 Reveals Persistent Immune Abnormalities in Convalescent Severe IndividualsImmunology Published on 2021-11-192022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] abnormality active infection adaptive immune responses Adults CD8+ T cells Cell comparison convalescent COVID-19 cytokine cytokine profile elevated endothelial growth factor hepatocyte growth factor immune immune correlate immune recovery immune response Immunophenotyping individual Inflammation low-density lymphopenia Mild neutrophil counts Neutrophils NKT non-classical monocyte persistent pro-inflammatory cytokine proportion SARS – CoV – 2 SARS-COV-2 infection severe COVID-19 severely infected patient severity survivor T cells Vascular virus clearance [DOI] 10.3389/fimmu.2021.710217 PMC 바로가기 [Article Type] Immunology
Subclinical Myocardial Dysfunction in Patients Recovered from COVID-19 Disease: Correlation with Exercise CapacityArticle Published on 2021-11-182022-10-28 Journal: Biology [Category] COVID-19, [키워드] abnormality age Capacity chest pain clinical Complication consecutive patient control patients correlation COVID-19 COVID-19 disease COVID-19 infection COVID-19 patients diastolic Dyspnea echocardiographic parameters Ejection fraction examined exercise Exercise capacity GLS groups identify longitudinal Myocardial strain no difference Patient patients performed prolong COVID-19 recovered Research risk factor severe disease significantly lower simple strain stress echocardiography Subclinical Symptom Symptoms the disease Treatment ventricular were assessed [DOI] 10.3390/biology10111201 PMC 바로가기 [Article Type] Article
Case Report: Bullous Lung Disease Following COVID-19Medicine Published on 2021-11-172022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] abnormality acute respiratory syndrome bullous bullous lung disease Case report changes chest radiological Coronavirus disease 2019 Coronavirus-2 COVID-19 Ground-glass opacities include Infection interlobular septal thickening Lung disease pandemic parenchymal Patient persistence post-acute COVID-19 post-COVID “Long Haulers” pulmonary disease radiological abnormality reported symptom respiratory manifestation SARS CoV-2 Symptom symptom onset [DOI] 10.3389/fmed.2021.770778 PMC 바로가기 [Article Type] Medicine
Persistent symptoms and decreased health-related quality of life after symptomatic pediatric COVID-19: A prospective study in a Latin American tertiary hospitalObservational Study Published on 2021-11-172022-10-04 Journal: Clinics [Category] MERS, SARS, 유전자 메커니즘, 임상, [키워드] abnormality Adolescent age alteration Anemia approach baseline body mass index C-reactive protein characteristic Child children chronic condition Concentration Control controls coronavirus disease COVID-19 COVID-19 diagnosis D-dimer level domains Dyspnea Echocardiogram evaluate Follow-up Frequency headache highlight hospital inventory laboratory-confirmed Latin Long Coronavirus Disease 2019 lymphopenia Male sex median multisystem inflammatory syndrome in children parameters Patient patients patients with COVID-19 pediatric Pediatric patient persistent physical score post-COVID-19 patient proportion Prospective Study Quality Quality of life reduced reported reported symptom Sequelae significantly significantly lower subject Symptom symptomatic tiredness was performed with COVID-19 X-ray [DOI] 10.6061/clinics/2021/e3511 PMC 바로가기 [Article Type] Observational Study
Altered increase in STAT1 expression and phosphorylation in severe COVID‐19Clinical Trial Published on 2021-11-172022-10-04 Journal: European Journal of Immunology [Category] MERS, SARS, 임상, [키워드] abnormality absence Altered antiviral defense mechanism baseline Biomarker CD14+ monocyte CD169 component correlated COVID‐19 COVID‐19 Cytokine storm downstream element expression flow cytometry IFN IFN signaling IFN‐γ Immune cell increase in induce interferon interferon pathway interferon signaling investigated IRF1 IRF9 ISRE JAK/STAT JAK/STAT signaling limit lower expression Mild mild cases monocyte Monocytes Patient PBMC Phosphorylation plasmablast Predictive pSTAT1 SARS‐CoV‐2 infection Severe case Severe infection severely infected patient Signaling STAT Stat1 STAT2 stimulated Stratification T cell target therapeutic target Transcription Transcriptional upregulation type I interferon upregulation [DOI] 10.1002/eji.202149575 PMC 바로가기 [Article Type] Clinical Trial
First Case of Erythema Nodosum Associated With Pfizer VaccineEmergency Medicine Published on 2021-11-132022-10-31 Journal: Cureus [Category] COVID-19, [키워드] abnormality absence Chest coronavirus disease COVID-19 cutaneous side effects eight Erythema erythema nodosum first dose healthy immune reaction Laboratory laboratory investigation nodule Pfizer receiving resolved Vaccine Vaccines [DOI] 10.7759/cureus.19529 PMC 바로가기 [Article Type] Emergency Medicine
Post COVID-19 pulmonary complications; a single center experienceCase Series Published on 2021-11-102022-10-28 Journal: Annals of Medicine and Surgery [Category] COVID-19, [키워드] abnormality Affect age average Bullectomy case sery Clinical data collected Complication complications conditions coronavirus 2019 disease COVID-19 COVID-19 patient death discharged disease Evidence female Fever FIVE hemoptysis hospital ICU ICU admission Infection intensive care involved male Mucormycosis Patient performed Post COVID-19 syndrome pulmonary pulmonary complication pulmonary complications Quality of life Result retrospective SARS-CoV-2 severe COVID-19 severity Shortness of breath single center Surgical Procedure syndrome the patient tomography [DOI] 10.1016/j.amsu.2021.103052 PMC 바로가기 [Article Type] Case Series
Clinical Characteristics of Children With COVID-19 in the United Arab Emirates: Cross-sectional Multicenter StudyOriginal Paper Published on 2021-11-052022-10-29 Journal: JMIR Pediatrics and Parenting [Category] COVID-19, [키워드] abnormality Admission age alkaline phosphatase Antibiotics Aspartate transaminase Asthma Asymptomatic Characteristics Chest children children with COVID-19 clinical Clinical characteristics collected conducted Confirmed COVID-19 infection Contact tracing cough Course courses COVID-19 COVID-19 infection cross-sectional demographics Dubai examined first positive had no hospital Hospitalization intensive care Laboratory laboratory abnormality lack lactate dehydrogenase median medications Mild moderate Most patient multicenter multicenter study Negative PCR neutrophil count no significant difference no symptom objective Outbreaks outcome outcomes pandemic participant Patient PCR PCR testing pediatric pediatrics polymerase chain positive premorbid presenting symptoms public health measure Public heath receiving reported reported symptom resolved Result rhinorrhea SARS-CoV-2 severe COVID-19 disease stability Surveillance symptomatic and asymptomatic Symptoms tested Treatment United Arab Emirate United Arab Emirates Variation viral shedding [DOI] 10.2196/29049 PMC 바로가기 [Article Type] Original Paper
Prevalence, prognostic value, pathophysiology, and management of hyponatraemia in children and adolescents with COVID-19COVID-19 소아 및 청소년의 유병률, 예후 가치, 병태생리 및 저나트륨혈증 관리Review Published on 2021-11-032022-09-11 Journal: Acta bio-medica : Atenei Parmensis [Category] Coronavirus, SARS, 치료기술, [키워드] abnormality administer aetiology association Bacterial bacterial pneumonia benefit children children with COVID-19 clinician Cochrane Library coronavirus disease Coronavirus disease 2019 COVID-19 Cytokine storm detect disorder evaluate facilitate fluids Frequency Immunomodulatory agents interleukin interleukin-6 literature literature review management marker MIS-C paediatric patient paediatric patients pathophysiology Patient Pneumonia poor prognosis Prevalence prognostic Prognostic value reported risk sodium therapy with COVID-19 [DOI] 10.23750/abm.v92i5.12330 PMC 바로가기 [Article Type] Review
Anti-inflammatory adipokines: chemerin, vaspin, omentin concentrations and SARS-CoV-2 outcomesArticle Published on 2021-11-022022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 진단, 치료제, [키워드] abnormality activity Admission analyzed applied chemerin collected Concentration Coronavirus disease 2019 Course COVID-19 COVID-19 patient COVID-19 symptom CRP deficiency disease pathogenesis disease severity Dyspnea elevated ferritin Frequency healthy controls healthy volunteer hospital Hospitalization ICU ICU admission Infection intensive care unit liver dysfunction Metabolic abnormality no correlation outcome Pathogenesis Pneumonia Predictive Prognostic markers SARS-CoV-2 serum severe COVID-19 severity significantly systemic inflammation Treatment were measured with COVID-19 [DOI] 10.1038/s41598-021-00928-w PMC 바로가기 [Article Type] Article