Spontaneous pneumothorax as unusual presenting symptom of COVID-19 pneumonia: surgical management and pathological findingsCase Report Published on 2020-10-122022-10-30 Journal: Journal of Cardiothoracic Surgery [Category] Coronavirus, MERS, SARS, [키워드] bleeding Blood Bullectomy Case report Chest COVID-19 COVID-19 patient disease histological examination hospital Infection infiltration initial interstitial interstitial pneumonia ipsilateral lung surgery lymphocyte management microthrombi Novel coronavirus parenchymal pathological finding pathology Patient performed Plasma cells Pneumonia Pneumothorax presenting reported Spontaneous pneumothorax surgical Surgical Procedure Symptom Thoracoscopy tissue treated Treatment Two patient vascular congestion vessel [DOI] 10.1186/s13019-020-01343-4 PMC 바로가기 [Article Type] Case Report
SARS-CoV-2 triggers inflammatory responses and cell death through caspase-8 activationArticle Published on 2020-10-092022-10-29 Journal: Signal Transduction and Targeted Therapy [Category] COVID-19, MERS, SARS, [키워드] activate Activation acute respiratory syndrome Analysis Apoptosis assist caspase-8 Cell cell death cell death pathway cell debris clinical manifestations coronavirus coronavirus disease COVID-19 COVID-19 patients critically ill patients fatal COVID-19 HFH4-hACE2 immune Infection Infectious diseases infiltration Inflammation Inflammatory cytokine Inflammatory cytokine storm Inflammatory response lung lung damage Lung epithelial cells massive inflammatory mechanism multi-organ failure necroptosis necrotic Pathogenesis pathway Patient processed pulmonary interstitial fibrosis released Respiratory illness SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pathogenesis therapeutic strategy Transgenic mouse treat Trigger triggered [DOI] 10.1038/s41392-020-00334-0 PMC 바로가기 [Article Type] Article
A severe coronavirus disease 2019 patient with high-risk predisposing factors died from massive gastrointestinal bleeding: a case reportCase Report Published on 2020-09-292022-10-27 Journal: BMC Gastroenterology [Category] COVID-19, [키워드] Administered age Bacterial infection bleeding Case report conditions Coronavirus disease 2019 Cross-infection described diarrhea died evidenced expired Factor gastrointestinal bleeding High-risk predisposing factors hypertension individual infection control infiltration male manifestation Manifestations massive nausea occurred Patient Patient care poor prognosis positive protocol public health threat radiological reported respiratory symptom resulting risk factor SARS-CoV-2 SARS-CoV-2 infected patients severe coronavirus disease severe SARS-CoV-2 specimens Stool suffered Symptom Transmission viral invasion vomiting [DOI] 10.1186/s12876-020-01458-x PMC 바로가기 [Article Type] Case Report
A severe coronavirus disease 2019 patient with high-risk predisposing factors died from massive gastrointestinal bleeding: a case reportCase Report Published on 2020-09-292022-10-27 Journal: BMC Gastroenterology [Category] Coronavirus, COVID-19, Fulltext, SARS, [키워드] Administered age Bacterial infection bleeding Case report conditions Coronavirus disease 2019 Cross-infection described diarrhea died evidenced expired Factor gastrointestinal bleeding High-risk predisposing factors hypertension individual infection control infiltration male manifestation Manifestations massive nausea occurred Patient Patient care poor prognosis positive protocol public health threat radiological reported respiratory symptom resulting risk factor SARS-CoV-2 SARS-CoV-2 infected patients severe coronavirus disease severe SARS-CoV-2 specimens Stool suffered Symptom Transmission viral invasion vomiting [DOI] 10.1186/s12876-020-01458-x PMC 바로가기 [Article Type] Case Report
Serum proteins may facilitate the identification of Kawasaki disease and promote in vitro neutrophil infiltrationArticle Published on 2020-09-242022-10-04 Journal: Scientific Reports [Category] 바이오마커, [키워드] activated Adhesion Molecule Affect age antibody applied attenuate Biomarkers cause children clinically conducted DEFA1 demonstrated develop Developing Diagnosis diagnostic Diseases ELISA endothelial endothelial cells enrolled evaluate facilitate glycoprotein immune immunology in vitro in vitro study infiltration Inflammatory Kawasaki disease lesion leukocyte Medical research Molecular medicine neutrophil neutrophil infiltration neutrophil surface neutrophil-like cell ORM1 Pathogenesis pathogenic patients potential mechanism potential therapeutic target PRDX2 promote promoted Protein Proteins proteomics reducing responsible rheumatology risk robust S100A12 S100A8 S100A9 Satisfaction serum Serum protein significantly subject Treatment [DOI] 10.1038/s41598-020-72695-z PMC 바로가기 [Article Type] Article
Complex Immunometabolic Profiling Reveals the Activation of Cellular Immunity and Biliary Lesions in Patients with Severe COVID-19Article Published on 2020-09-172022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Activation acute kidney failure Acute kidney injury acute respiratory syndrome adaptive Biliary biliary lesion CD8 T cells Cell cellular Characteristics characterized cholestasis coronavirus coronavirus disease Course COVID-19 disease Follow-up GGT granulocyte hepatopathy histological IL-6 immature immune response Immunity infiltration Inflammation Inpatient laboratory feature lesion Liver disease marker Mild moderate organ pathophysiology Patient Profiling progressed proinflammatory SARS-CoV-2 serum T cells the disease university [DOI] 10.3390/jcm9093000 PMC 바로가기 [Article Type] Article
The potential role of microvascular pathology in the neurological manifestations of coronavirus infectionReview Published on 2020-09-102022-10-31 Journal: Fluids and Barriers of the CNS [Category] COVID-19, SARS, [키워드] acute respiratory syndrome blood–brain barrier cardiovascular disease Central nervous system CNS conditions coronavirus Coronavirus infection COVID-19 cytokine profile diabetes diagnostic disease dysfunction facilitate Fluorescein Future Health highly pathogenic Human hypertension Hypothesis include infiltration likelihood MERS-CoV Middle East MRI neurological neurological manifestation Neurological symptoms NEUROLOGY outbreak pandemic pathogenic pathology respiratory SARS-CoV-1 SARS-CoV-2 serum biomarkers stroke Thromboembolism Vascular damage virus [DOI] 10.1186/s12987-020-00216-1 PMC 바로가기 [Article Type] Review
Variety of radiological findings in a family with COVID-19: a case reportCase Report Published on 2020-09-092022-10-31 Journal: The Egyptian Journal of Radiology and Nuclear Medicine [Category] COVID-19, [키워드] Affect affected Asymptomatic Atypical Case report case sery cause Chest computed tomography Chest CT chest CT scan children China clinical symptom clinician close contact condition conditions coronavirus disease cough COVID-19 COVID-19 transmission demonstrated diagnosis of COVID-19 diarrhea discharged Dyspnea expired feature Fever ground-glass opacity identify infected with COVID-19 infiltration interlobular septal thickening left lower lobe less lobar lung Lungs lymphopenia manifestation Mild Older patchy pediatric Pneumonia radiological finding regimen reported Symptom Transmissibility Treatment variety with COVID-19 Wuhan [DOI] 10.1186/s43055-020-00293-0 PMC 바로가기 [Article Type] Case Report
Lessons for the clinical nephrologist: recurrence of nephrotic syndrome induced by SARS-CoV-2Lesson for the Clinical Nephrologist Published on 2020-09-052022-10-30 Journal: Journal of Nephrology [Category] COVID-19, MERS, [키워드] Acute kidney injury Allograft Autopsy cells characterized contribute COVID-19 expand glomerular Immunosuppression indicated infect infiltration initial Injury kidney kidneys lesson male Multiorgan pandemic Patient plasma Podocytopathy positive recent recipients recovering from COVID-19 renal Renal involvement resolved RNA SARS-CoV-2 supplementary material syndrome tubular cell was tested [DOI] 10.1007/s40620-020-00855-5 PMC 바로가기 [Article Type] Lesson for the Clinical Nephrologist
SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function Research Published on 2020-08-242022-10-05 Journal: Nature Immunology [Category] SARS, 유전자 메커니즘, 진단, [키워드] ACE2 activated T cells acute respiratory syndrome animal model can be used cause coronavirus driven by enzyme evaluate evaluated expressing feature Hospitalized Human immune impaired function Infection infiltration innate immune response interferon signaling K18 K18-hACE2 K18-hACE2 mice leukocyte activation Lung disease lung tissue Lungs mice Monocytes neutrophil nuclear occur other organs Pathways phenotype promoter Pulmonary function receptor SARS-CoV-2 SARS-COV-2 infection Severe COVID-19 Infection severe lung inflammation spread to to define transgenic mice type I upregulated viral infection viral titer [DOI] 10.1038/s41590-020-0778-2 [Article Type] Research