Meningitis

[키워드] adjusted Adults adverse event adverse events African age All participants analysed Antigen assigned baseline block block size block sizes blocks blood sample Blood samples Comparisons death Deltoid muscle dose dose-escalation double-blind Efficacy elicited eligible enrolment evaluate febrile febrile convulsion Final finding FIVE foundation funding geometric mean geometric mean titre gestation GRADE group groups HIV infection IgA IgG IgG seroresponse IgG seroresponses immunogenic immunogenicity immunogenicity endpoint Infant Infants injection Injections Intramuscular injection Laboratory Local Melinda Gate Melinda Gates Meningitis multisite neutralising antibody neutralising antibody response Neutralising antibody responses neutralising antibody seroresponse neutralising antibody seroresponses no significant difference no significant differences occurred parent parents participant Participants Placebo placebo group placebo recipient placebo recipients placebo-controlled placebo-controlled trial pneumococcal pneumococcal meningitis protocol randomisation randomised Randomly receive recipient Registered Research respiratory Respiratory tract infections response responses against rotavirus vaccination rotavirus vaccine Safety safety endpoint Serious Adverse Event Serious Adverse Events serum significantly higher South South Africa Strains subunit Support systemic adverse events systemic reaction systemic reactions the placebo group the vaccine timepoints Treatment Trial trivalent USA Vaccine was done were assessed
[DOI] 10.1016/S1473-3099(20)30001-3 PMC 바로가기 [Article Type] Article