Time course of peripheral immunophenotypes of multisystem inflammatory syndrome in childrenArticle Published on 2022-03-012023-07-08 Journal: Clinical immunology (Orlando, Fla.) [Category] COVID19(2023년), [키워드] antibody IgG MIS-C SARS-CoV-2 Spike protein Vβ 21.3. [DOI] 10.1016/j.clim.2022.108955 PMC 바로가기
Severe Multisystem Inflammatory Syndrome Associated With SARS‐CoV‐2 in a 31-Year-Old Male Patient: The First Clinical Case Report From the Republic of CyprusInternal Medicine Published on 2022-02-262022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory distress syndrome [ards] Anticoagulant C-reactive protein cause children clinical Clinical improvement Corticosteroids covid-19 mis-c CRP Cyprus diagnostic differential diagnosis Ejection fraction elevated exclusion Fever immunoglobulins include increasingly Infection Inflammatory intensive care unit male Mild MIS MIS-C multisystem inflammatory syndrome in adults [mis-a] Patient PCT procalcitonin reduced report reported sars-cov-2 (severe acute respiratory syndrome coronavirus -2) SARS‐CoV‐2 SARS‐CoV‐2 infection Shock syndrome Treatment treatment guideline [DOI] 10.7759/cureus.22640 PMC 바로가기 [Article Type] Internal Medicine
SARS-CoV-2-Associated Multisystem Inflammatory Syndrome in a Child in Uganda: A Paediatric Experience in a Resource-Limited SettingCase Report Published on 2022-02-232022-10-31 Journal: Case Reports in Infectious Diseases [Category] COVID-19, [키워드] African Case report Child children clinical feature clinical suspicion COVID-19 cases described Diagnosis experience facilitate Health IMPROVE MIS-C morbidity Mortality outcomes raise reported setting Treatment Uganda [DOI] 10.1155/2022/7811891 PMC 바로가기 [Article Type] Case Report
Potentially effective drugs for the treatment of COVID-19 or MIS-C in children: a systematic review소아에서 COVID-19 또는 MIS-C 치료를 위한 잠재적으로 효과적인 약물: 체계적인 검토Original Article Published on 2022-02-222022-09-12 Journal: European journal of pediatrics [Category] MERS, 진단, [키워드] 95%CI adverse events association case sery children Clinical efficacy Clinical symptoms clinical trial cohort study control group COVID-19 died drug effective drug Effectiveness Efficacy and safety evaluate Evidence extracorporeal membrane oxygenation glucocorticoid Glucocorticoids Google Intravenous immunoglobulin Invasive mechanical ventilation mechanical ventilation Meta-analysis Methylprednisolone MIS-C Mortality nine Odds ratio Patient platform Randomized controlled trial Remdesivir searched Seven shown single-arm supplementary material systematic review Treatment were used with COVID-19 [DOI] 10.1007/s00431-022-04388-w PMC 바로가기 [Article Type] Original Article
Limited induction of SARS-CoV-2–specific T cell responses in children with multisystem inflammatory syndrome compared with COVID-19COVID-19에 비해 다기관 염증 증후군 아동에서 SARS-CoV-2-특이 T 세포 반응의 제한된 유도Research Article Published on 2022-02-222022-09-10 Journal: JCI Insight [Category] COVID19(2023년), MERS, SARS, 치료법, [키워드] Adaptive immunity B cell responses CD4 CD8 Cellular immune response children contribute convalescent COVID-19 cytokine cytokine production cytokine response demonstrated develop full-length functional healthy controls Inflammatory Limited MIS-C mononuclear cell mononuclear cells nucleocapsid participant Pathogenesis peptides Peripheral blood Peripheral blood mononuclear cells plasma predominant quantified RBD Receptor binding domain responses against SARS-CoV-2 antigen SARS-COV-2 infection serologic Serologic response serologic responses significantly lower Spike receptor binding domain subset Support syndrome T cell T cell response T cell responses T cells Th1 Viral Viral proteins was reduced with COVID-19 [DOI] 10.1172/jci.insight.155145 PMC 바로가기 [Article Type] Research Article
Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19 Research Published on 2022-02-172022-10-05 Journal: Nature Medicine [Category] COVID19(2023년), SARS, 바이오마커, 변종, 유전자 메커니즘, 치료기술, 치료법, [키워드] Activation acute respiratory syndrome Admission allele Analysis applied association B cell Biomarkers characterized children children with COVID-19 circulating Combination coronavirus COVID-19 develop disorder Gene Expression genetic susceptibility healthy control help HLA identify IFN immune immunopathological Inflammation Inflammatory MIS-C morbidity Mutation no correlation pathophysiology pediatric proteomics responses robust SARS-CoV-2 SARS-CoV-2 PCR single-cell Spike protein syndrome T cell T cell activation therapy Transient TRBV11-2 type I interferon [DOI] 10.1038/s41591-022-01724-3 [Article Type] Research
Association between Coagulation Profile and Clinical Outcome in Children with SARS-CoV-2 Infection or MIS-C: A Multicenter Cross-Sectional StudyArticle Published on 2022-02-172022-10-31 Journal: Children [Category] COVID-19, [키워드] activated Admission affected age Blood children clinical clinical history Clinical outcome Coagulation collected COVID-19 cross-sectional D-dimer D-dimer value D-dimer values D-dimers diagnosed with COVID-19 Diagnosis died enrolled evaluate fibrinogen value higher risk increased risk Infection Inflammatory INR intensive care International IQR Limited management median age MIS-C multicenter multivariate logistic regression normalized outcome Patient pediatric performed Platelet predictor profile retrospective SARS-CoV-2 syndrome the patient the SARS-CoV-2 Univariate analysis [DOI] 10.3390/children9020279 PMC 바로가기 [Article Type] Article
Global Research Trends in Pediatric COVID-19: A Bibliometric AnalysisPublic Health Published on 2022-02-162022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] Analysis article articles authors bibliometric analysis caused center childhood children China clinical study co-occurrence conducted contributed Coronavirus disease 2019 country COVID-19 COVID-19 research criteria database English Frequency global pandemic Health healthcare hotspot identify Impact impacted Inflammatory Italy Leiden mental health Microsoft Excel MIS-C Netherlands pandemic pediatric Psychological ranged Research research hotspot Research trends Result Science screened searched selected Shanghai shifting syndrome technology trend United State United States university VOSviewer was used Web of Science [DOI] 10.3389/fpubh.2022.798005 PMC 바로가기 [Article Type] Public Health
Long COVID in Children and AdolescentsReview Published on 2022-02-142022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] acute phase acute respiratory syndrome acute SARS-CoV-2 infection Adolescent Asymptomatic caused children Complication consequence control group coronavirus 2 COVID COVID-19 develop Effect IMPROVE Inflammatory knowledge life-threatening Long Long COVID management MIS-C morbidity Mortality Neuropsychiatric Neuropsychiatric symptoms Pandemics pediatric Prevalence Prevent Prognosis psychological support Quality of life raise report Research resulting SARS-CoV-2 SARS-COV-2 infection Stress Symptom syndrome Treatment while [DOI] 10.3390/life12020285 PMC 바로가기 [Article Type] Review
A Comprehensive Review of Neuromuscular Manifestations of COVID-19 and Management of Pre-Existing Neuromuscular Disorders in ChildrenReview Published on 2022-02-112022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] alleviate Cardiomyopathy children clinical care Complication Comprehensive COVID-19 COVID-19 pandemic disorder disorders include management manifestation MIS-C muscular muscular dystrophy Neuromuscular Patient patients pediatric Research Restrictive lung disease review risk SARS-CoV-2 scoliosis severe complication spinal muscular atrophy Telemedicine the disease Treatment [DOI] 10.3390/jcm11040934 PMC 바로가기 [Article Type] Review