Repurposing Treatment of Wernicke–Korsakoff Syndrome for Th-17 Cell Immune Storm Syndrome and Neurological Symptoms in COVID-19: Thiamine Efficacy and Safety, In-Vitro Evidence and Pharmacokinetic ProfilePharmacology Published on 2021-03-022022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] Administered alcohol Anti-inflammatory clinical study condition Control COVID-19 COVID-19 cytokine storm COVID-19 patient Cytokine storm disease disorder dose doses effective Effectiveness elevated healthy volunteer humans identify IL-17 IL-22 immune in vitro study increase in Intervention literature review macrophage cell line measure metabolic conditions Neurological symptom occur pandemic Patient patients pharmacokinetic profile proinflammatory Proinflammatory cytokine Proinflammatory response repurposing respond Safe Safety Septic shock severe cases significantly storm subsequent tested Th17 Th17 response the cytokine storm Thiamine treated Treatment viral infection was performed [DOI] 10.3389/fphar.2020.598128 PMC 바로가기 [Article Type] Pharmacology
Neuropsychiatric and Cognitive Sequelae of COVID-19Psychology Published on 2021-03-022022-10-31 Journal: Frontiers in Psychology [Category] COVID-19, [키워드] acute respiratory syndrome addition Autopsy Brain Cognition cognitive Coronavirus disease 2019 COVID-19 COVID-19 patient Depression develop disorders Effect evaluate Evidence global pandemic headache Health care worker impacted implication include individual Infection manifestation mental health Mental health disorder mental health problem MONITOR nervous system neurodegeneration Neurological symptom Neuropsychiatric neuropsychiatric disease oedema paraesthesia pathology pathophysiological mechanism pathophysiology patients problems Psychiatric Psychiatric disorders Symptom tissue viral respiratory infections virus with COVID-19 [DOI] 10.3389/fpsyg.2021.577529 PMC 바로가기 [Article Type] Psychology
High frequency of cerebrospinal fluid autoantibodies in COVID-19 patients with neurological symptoms신경계 증상이 있는 코로나19 환자에서 뇌척수액 자가항체의 높은 빈도Article Published on 2021-03-012022-09-12 Journal: Brain, behavior, and immunity [Category] MERS, 진단, [키워드] absence analyzed autoantibodies autoantibody autoantigen Autoimmunity binding Brain brain tissue cerebrospinal fluid Clinical symptoms COVID-19 COVID-19 patient Critically ill CSF delirium disease Encephalitis Endothelium Epitopes explain Frequency ganglia hyperexcitability immunofluorescence Immunotherapy intensive care patient monoclonal murine neurological Neurological symptom NEUROLOGY neuronal NMDA olfactory Patient potential molecular presenting Protein receptor SARS-CoV-2 SARS-CoV-2 antibodies Seizures selected serum surface proteins Undetermined vessel Viral-triggered. virus-neutralizing antibody [DOI] 10.1016/j.bbi.2020.12.022 PMC 바로가기 [Article Type] Article
Sudomotor dysfunction in patients recovered from COVID-19COVID-19에서 회복된 환자의 운동 기능 장애Observational Study Published on 2021-03-012022-09-11 Journal: Neurophysiologie clinique = Clinical neurophysiolo [Category] 임상, 치료제, [키워드] Antiviral treatment autonomic COVID-19 Dysautonomia dysfunction Electrochemical skin conductance fiber Neurological symptom Neurological symptoms Neuropathy NHS observational study Older participated Patient patients with COVID-19 questionnaire reported screened small fiber small fiber neuropathy Sweat Symptom treated was measured [DOI] 10.1016/j.neucli.2021.01.003 PMC 바로가기 [Article Type] Observational Study
Adie-Holmes syndrome associated with COVID-19 infection: A case reportCOVID-19 감염과 관련된 Adie-Holmes 증후군: 증례 보고Case Reports Published on 2021-03-012022-09-11 Journal: Indian journal of ophthalmology [Category] SARS, 치료기술, [키워드] Adiefs tonic pupil anisocoria blurred vision Brain Case report caused COVID-19 COVID-19 infection nervous system neurological Neurological involvement Neurological symptom neurological symptom. neurotropic photophobia pupil SARS-CoV-2 virus suggested Symptom syndrome the SARS-CoV-2 virus tonic pupil with COVID-19 [DOI] 10.4103/ijo.IJO_3589_20 PMC 바로가기 [Article Type] Case Reports
Evidence of central nervous system infection and neuroinvasive routes, as well as neurological involvement, in the lethality of SARS-CoV-2 infectionSARS-CoV-2 감염의 치사율에 대한 중추 신경계 감염 및 신경 침습 경로 및 신경학적 관여의 증거Review Published on 2021-03-012022-09-11 Journal: Journal of medical virology [Category] SARS, 치료기술, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Brain cause of death caused Central nervous system cerebrospinal fluid clinical symptom Clinical symptoms CNS coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 patient COVID-19 patients CSF dead death early stage Evidence evidence of global health Gustatory Health higher risk Hypothesis in vitro in vivo experiment Infection infection with SARS-CoV-2 lethality mechanism Mortality nervous system neuroinvasion Neuroinvasive neurological Neurological deficit neurological deficits Neurological involvement Neurological symptom Neurological symptoms Neuron neurons Neuropathology nine olfactory outbreak pathophysiology Pathways Patient positive provided reported SARS-CoV-2 SARS-COV-2 infection Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe COVID-19 severe COVID-19 patients Support [DOI] 10.1002/jmv.26570 PMC 바로가기 [Article Type] Review
Encephalopathy and encephalitis during acute SARS-CoV-2 infection. Spanish Society of Neurology COVID-19 Registry급성 SARS-CoV-2 감염 중 뇌병증 및 뇌염. 스페인 신경 학회 COVID-19 등록Observational Study Published on 2021-03-012022-09-11 Journal: Neurología (Barcelona, Spain) [Category] SARS, 임상, 진단, 치료기술, [키워드] acute SARS-CoV-2 infection alteration brain MRI Characteristics Coma Complication complications conducted Confusion confusional Corticosteroid Corticosteroids COVID-19 COVID-19 pandemic Encefalitis Encefalopatías Encephalitis Encephalopathy healthcare professionals Immunoglobulin immunoglobulins Infection lumbar Lumbar puncture men Mild moderate multicentre Neurological involvement Neurological symptom Neurological symptoms NEUROLOGY Patient patients patients treated performed positive PCR positive PCR result presenting progressed Registered Registro SEN registry reported retrospective SARS-CoV-2 SARS-CoV2 SEN registry. Society Spanish Symptom syndrome was performed women [DOI] 10.1016/j.nrl.2020.11.013 PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2 Infection and Disease Modelling Using Stem Cell Technology and Organoids줄기 세포 기술 및 오르가노이드를 사용한 SARS-CoV-2 감염 및 질병 모델링Review Published on 2021-02-262022-09-12 Journal: International Journal of Molecular Sciences [Category] MERS, 진단, [키워드] ACE2 airway epithelial cells alveolar Apoptosis cardiovascular system Cell cell damage cells Central nervous system Choroid plexus Clinical studies clinical study colonic contribute demonstrated Direct disease Endothelial cell endothelial cells Enterocyte enterocytes epithelial epithelial cells gastrointestinal tract highlighting human host Hypothesis immunological impairing in vitro model indirect effect indirect effects infect infected individuals Inflammation innate immune response intestinal organoid lung lung alveolar lung epithelia mechanism Neurological symptom Neurological symptoms Neuron neurons Organoid organoids organs Pathogenesis pathogenesis of SARS-CoV-2 replicate review SARS-CoV-2 SARS-CoV-2 cell SARS-COV-2 infection SARS-CoV-2 pathogenesis STEM stem cell surfactant susceptible systemic inflammatory target technology Trigger triggers tropism type I variance Vascular damage Viral viral damage viral infection virus [DOI] 10.3390/ijms22052356 PMC 바로가기 [Article Type] Review
Neurological symptoms in Covid‐19 patients in the emergency departmentOriginal Research Published on 2021-02-222022-10-28 Journal: Brain and Behavior [Category] COVID-19, MERS, [키워드] 95% confidence interval Admission Altered mental status analyzed Anosmia cohort study Coronavirus disease 2019 COVID‐19 described Diagnosis died evaluate female Frequency had no headache Hospitalized hospitalized patients independent Laboratory Laboratory results lower risk Mortality myalgia Nervous system diseases Neurological symptom Neurological symptoms Olfaction disorders Patient polymerase chain predicted predictors presented later Prognosis Result sensitivity serology symptomatic Symptoms variable [DOI] 10.1002/brb3.2058 PMC 바로가기 [Article Type] Original Research
Neurological Disorders Associated With COVID-19 Hospital Admissions: Experience of a Single Tertiary Healthcare CenterNeurology Published on 2021-02-192022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] addition Admission age Anosmia Autoimmune categories center Cohort Confusion COVID-19 COVID-19 infection COVID-19 patient Critical care database delirium determine diagnosed disorder Effect Encephalitis Encephalopathy etiology event experience Features FIVE Follow-up functional Hemorrhagic hospitalized COVID-19 patients hospitalized patient incidence Infection Inflammatory Inpatient Laboratory lack longitudinal males Multiple nervous system neurological deficits Neurological disorder Neurological disorders neurological phenotype Neurological symptom Neurological symptoms NEUROLOGY non-specific outcome Patient Prevalence radiological required sclerosis Seizures Seven stroke Tertiary the SARS-CoV-2 the WHO Treatment response [DOI] 10.3389/fneur.2021.640017 PMC 바로가기 [Article Type] Neurology