reduced risk – Page 16 – Communicable Diseases Research

Oral Bacteriotherapy in Patients With COVID-19: A Retrospective Cohort Study

Nutrition

Published on 2021-01-112022-10-31
Journal: Frontiers in Nutrition [Category] COVID-19,

A data-driven approach to identify risk profiles and protective drugs in COVID-19

COVID-19의 위험 프로필 및 보호 약물을 식별하기 위한 데이터 기반 접근 방식

530

Published on 2021-01-052022-09-10
Journal: Proceedings of the National Academy of Sciences of [Category] MERS, SARS, 치료제,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 applied approach Bayesian network Bayesian networks binding cardiometabolic cardiometabolic risk factor Cardiometabolic risk factors collected complex coronavirus correlated covariate COVID-19 COVID-19 case COVID-19 cases COVID-19 infection COVID-19 infections COVID-19 pandemic COVID-19 patients data-driven demographic characteristics develop drug drug regimens Effects Evidence highlight hospitalized patient hospitalized patients host cell host cells identify In-hospital death inhibitor initial investigated medication outbreak patient survival patients hospitalized profile Protective protective effect RAAS RAASi Randomized controlled trial Randomized controlled trials reduced risk reducing respiratory risk risk factor Risk factors risk of death risk reduction risk stratification SARS-CoV-2 SARS-CoV-2 virus severe acute respiratory syndrome Coronavirus Significance Standard statistical survival survival tree susceptibility the disease Therapeutic strategies to define Treatment virus with COVID-19
[DOI] 10.1073/pnas.2016877118 PMC 바로가기 [Article Type] 530

Design and Rationale of a Randomized, Double-Blind, Placebo-Controlled, Phase 2/3 Study Evaluating Dociparstat in Acute Lung Injury Associated with Severe COVID-19

Clinical Trial

Published on 2021-01-012022-10-05
Journal: Advances in therapy [Category] SARS, 임상,

[키워드] acute lung injury added advance anti-inflammatory properties approach Biomarker bleeding cause caused coagulation disorder Cohort contributed COVID-19 Critical care D-dimer determine Dexamethasone Dociparstat double-blind Efficacy Emergency use endpoints enrolled Evaluating Extracellular global pandemic HMGB1 hospital hospital ward Hospitalized hypercoagulable Hyperinflammatory Hypoxemia IL-6 Infection lung mechanical ventilation morbidity and mortality NETs Neutrophil extracellular traps New NIAID Novel coronavirus P-selectin participant pathology Patient patients patients with COVID-19 performed phase Phase 2 phase 2/3 trial Phase 3 Placebo placebo-controlled platelet factor 4 Platelet factor 4. positive primary endpoint proportion Randomized rationale reduced risk Respiratory failure robust SARS-CoV-2 sodium Standard of care subsequent supplemental oxygen treat with COVID-19
[DOI] 10.1007/s12325-020-01539-z PMC 바로가기 [Article Type] Clinical Trial

Impact of corticosteroids and immunosuppressive therapies on symptomatic SARS-CoV-2 infection in a large cohort of patients with chronic inflammatory arthritis

만성 염증성 관절염 환자의 대규모 코호트에서 증상이 있는 SARS-CoV-2 감염에 대한 코르티코스테로이드 및 면역억제 요법의 영향

Clinical Trial

Published on 2020-12-302022-08-09
Journal: Arthritis Research & Therapy [Category] MERS, 임상,

[키워드] acute respiratory illness acute respiratory syndrome adjusted Administered age appear Arthritis arthritis outpatient clinic Background Prevalence Biologic drugs Chronic inflammatory arthritis Comorbidities Comorbidity conducted consecutive patient consecutive patients coronavirus coronavirus disease Coronavirus Disease (COVID)-19 Corticosteroid cough COVID-19 COVID-19 case COVID-19 cases COVID-19 outbreak criteria cross-sectional survey csDMARDs defined Definition drug Dyspnea dyspnea) Effect endemic area evaluated Fever glucocorticoid Glucocorticoids Health Organization highly suspicious infection hospital Immune-mediated immunomodulatory medication immunomodulatory medications immunosuppressive agent Immunosuppressive agents immunosuppressive therapy Impact increased risk independent Infection Inflammatory arthritis Italy Laboratory-confirmed COVID-19 large cohort lombardy low-dose medications medications on COVID-19 nasopharyngeal Nasopharyngeal swab not applicable Occurrence outcome Patient patients treated Prevalence receiving reduced risk Registered respiratory Result Rheumatic diseases Safe SARS-CoV-2 Severe acute respiratory syndrome Sex study population symptomatic SARS-CoV-2 infection Treatment Trial registration were recorded World Health Organization World Health Organization criteria
[DOI] 10.1186/s13075-020-02395-6 PMC 바로가기 [Article Type] Clinical Trial

Direct oral anticoagulant use and risk of severe COVID‐19

Brief Report

Published on 2020-12-192022-10-30
Journal: Journal of internal medicine [Category] COVID-19, MERS, SARS,

Correlation between hospitalized patients’ demographics, symptoms, comorbidities, and COVID-19 pandemic in Bahia, Brazil

Research Article

Published on 2020-12-142022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS, SARS,

[키워드] 95% CI Admission age analyzed Brazil Chronic kidney disease Comorbidities conducted confidence correlation COVID-19 COVID-19 pandemic COVID-19 patient dataset demographics Diagnosis Hospital stay Hospitalized hospitalized patient increased risk initial symptom intensive care interval Linear regression Mortality multivariable multivariable logistic regression Older age outcome Patient presence of comorbidities provided Ratio reduced risk retrospective cohort study risk Secretary selected Shortness of breath sore throat state statistically statistically significant Symptom Symptoms the patient variable
[DOI] 10.1371/journal.pone.0243966 PMC 바로가기 [Article Type] Research Article

High-Dose Cholecalciferol Booster Therapy is Associated with a Reduced Risk of Mortality in Patients with COVID-19: A Cross-Sectional Multi-Centre Observational Study

고용량 콜레칼시페롤 부스터 요법은 COVID-19 환자의 사망률 감소와 관련이 있습니다: 횡단면 다중 센터 관찰 연구

Clinical Trial

Published on 2020-12-112022-08-13
Journal: Nutrients [Category] MERS, SARS, 임상,

[키워드] 2019 novel coronavirus 2019 novel coronavirus disease 25-hydroxyvitamin D 95% CI affected appear baseline carried cholecalciferol cholecalciferol booster therapy cholecalciferol therapy clinical trial Cohort collected confounder coronavirus disease COVID-19 COVID-19 mortality determine disease Efficacy hospitalised in-patient Logistic regression Mortality Novel coronavirus novel coronavirus 2019 novel coronavirus disease observational study participant Patient patients pharmacological management population studies predictor predictors public health recruited reduced risk replicated SARS-CoV-2 serum serum 25-hydroxyvitamin D therapeutic option therapeutic options Treatment UK hospitals validation cohort Vitamin D Vitamin D status vitamin D treatment was used with COVID-19 worldwide pandemic
[DOI] 10.3390/nu12123799 PMC 바로가기 [Article Type] Clinical Trial

Community interventions in Low—And Middle-Income Countries to inform COVID-19 control implementation decisions in Kenya: A rapid systematic review

Research Article

Published on 2020-12-082022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS, SARS, 신종인플루엔자,

[키워드] 95% CI acute respiratory syndrome approach Asia certainty of evidence China combined use Community Compliance COVID-19 demonstrated disease duplicates effective Effectiveness Epidemics Europe Evidence Face mask Face masks Factor FIVE Google Google Scholar Guidance H1N1 hygiene implementation inclusion criteria Infection Influenza Intervention intervention study Kenya Local measure MERS mitigate outbreak physical distance public health measure reduce reduced risk Registered reported resources respiratory infectious disease risk risk of bia robust Romania screened searched shown social distancing South America Spread syndrome systematic review the disease Transmission Transmission dynamics was reduced WHO with COVID-19 World Health Organization
[DOI] 10.1371/journal.pone.0242403 PMC 바로가기 [Article Type] Research Article

A systematic review of corticosteroid treatment for noncritically ill patients with COVID-19

Article

Published on 2020-12-012022-10-04
Journal: Scientific Reports [Category] MERS, SARS, 임상, 치료기술, 치료법,

[키워드] Abstract association Corticosteroid corticosteroid treatment COVID-19 COVID-19 therapy Critical Critical case Diseases Evidence FIVE Guidance Hospitalization ill patient in-hospital mortality intubation Medical research Mild moderate Mortality observational studies observational study outcome outcomes oxygen Patient patients propensity score matching Randomized controlled trial RCT RCTs recommendation recovery RECOVERY trial reduced risk screened Seven statistical significance Support systematic review systemic corticosteroid the WHO Treatment Trial viral shedding WHO with COVID-19 World Health Organization
[DOI] 10.1038/s41598-020-78054-2 PMC 바로가기 [Article Type] Article

Where have the children with epilepsy gone? An observational study of seizure-related accesses to emergency department at the time of COVID-19

Observational Study

Published on 2020-12-012022-10-05
Journal: Seizure [Category] SARS, 임상,

[키워드] accompanied age Care changed Child Child neurology children contributed COVID-19 COVID-19 pandemic decrease Emergency epilepsy evaluated examined Factor Health hospital Hospitalization hospitals Infection Italy lockdown measure parental pediatric reduced risk Rome School Seizure Sex significant changes in social distancing Turin
[DOI] 10.1016/j.seizure.2020.09.025 PMC 바로가기 [Article Type] Observational Study