Technical considerations to development of serological tests for SARS-CoV-2Review Published on 2021-03-012023-07-02 Journal: Talanta [Category] SARS, [키워드] COVID-19 immunoassays lateral flow assay rapid diagnostics SARS-CoV-2 Serological testing [DOI] 10.1016/j.talanta.2020.121883 PMC 바로가기 [Article Type] Review
False-positive results of SARS-CoV-2 IgM/IgG antibody tests in sera stored before the 2020 pandemic in Italy이탈리아에서 2020년 대유행 이전에 보관된 혈청에서 SARS-CoV-2 IgM/IgG 항체 검사의 위양성 결과Article Published on 2021-03-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Antibody detection Antibody test Aside be positive carried Chain Reaction collected conditions Control control patient coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 detect diagnostic value ELISA ELISA test enzyme enzyme-linked immunosorbent assays False-positive FIVE highlight human serum IgG IgG antibodies IgG positivity IgM IgM/IgG IgM/IgG antibodies Immunoglobulin Immunoglobulin G immunoglobulin M individual Infection Italy Lateral flow test Lateral flow tests nine oral swab outbreak pandemic pathologic Patient polymerase chain reaction positive positive controls positive sample Rapid reactivity real-time reverse transcription-polymerase chain reaction respiratory rRT-PCR SARS-CoV-2 SARS-CoV-2 virus sera serological test Serological testing Serological tests severe acute respiratory syndrome Coronavirus shown specimen specimens test results the SARS-CoV-2 virus Treatment urea utility variety virus [DOI] 10.1016/j.ijid.2020.12.067 PMC 바로가기 [Article Type] Article
Estimating the cumulative incidence of SARS-CoV-2 with imperfect serological tests: Exploiting cutoff-free approaches불완전한 혈청 검사로 SARS-CoV-2의 누적 발생률 추정: 차단 없는 접근 방식 활용Research Article Published on 2021-02-262022-09-12 Journal: PLoS Computational Biology [Category] MERS, 진단, [키워드] Accuracy antibody Antibody Response Antibody responses approach Asymptomatic asymptomatic infection Blood can be used circumvent confirmed case confirmed cases controls cumulative cumulative incidence Cutoff determine distribution elicit error estimate estimation False negative false negative results False positive fraction Guidance identify incidence individual individuals Infection leads less marker measure Measures Mild mixture model outperform pandemic parameter pathogen Pathogens Population Prevalence provided quantitative test required SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 pandemic SARS-CoV-2 specific antibodies SARS-CoV-2 specific antibody Sensitivity and specificity sera serological serological test Serological testing Serological tests seropositive seropositive individual seropositive individuals Serosurvey Serosurveys serum specific antibodies specific type specific types statistical statistical inference the SARS-CoV-2 to define yielding [DOI] 10.1371/journal.pcbi.1008728 PMC 바로가기 [Article Type] Research Article
Health Care Professionals’ Confidence and Preferences for Diagnostic Assays for SARS-CoV-2: A Global StudySARS-CoV-2 진단 분석에 대한 의료 전문가의 자신감과 선호: 글로벌 연구Public Health Published on 2021-02-262022-09-12 Journal: Frontiers in Public Health [Category] MERS, 진단, [키워드] Accuracy Antibody testing Antigen Care Characteristics Clinical use confidence Consensus correlated country COVID-19 COVID-19 pandemic COVID-19 test COVID-19 tests determine diagnostic diagnostic test diagnostics disease disease symptoms global health group had no hcp Health immune response infection with SARS-CoV-2 Mortality National PCR testing performed Perspective positive preference professional Result SARS-CoV-2 Serological testing Support [DOI] 10.3389/fpubh.2021.569315 PMC 바로가기 [Article Type] Public Health
Diagnosis of COVID-19 in Patients with Negative Nasopharyngeal Swabs: Reliability of Radiological and Clinical Diagnosis and Accuracy versus SerologyBrief Report Published on 2021-02-252022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Accuracy antibodies chest CT-scan clinical Clinical diagnosis clinical evaluation clinician Clinicians Coronavirus disease 2019 COVID-19 COVID-19 diagnosis Deceased Diagnosis diagnosis of COVID-19 eligible evaluated Follow-up Hospitalization interstitial pneumonia Nasopharyngeal swab negative negative swabs new coronavirus SARS-CoV-2 Patient patients patients died patients hospitalized protocol radiologic radiologist Radiologists reliability sensitivity serologic test Serological testing serology specificity symptomatic patient test negative treated were excluded [DOI] 10.3390/diagnostics11030386 PMC 바로가기 [Article Type] Brief Report
Diagnostic performance of COVID‐19 serological assays during early infection: A systematic review and meta‐analysis of 11 516 samples초기 감염 중 COVID-19 혈청학적 검사의 진단 성능: 11 516개의 샘플에 대한 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-02-202022-09-12 Journal: Influenza and Other Respiratory Viruses [Category] MERS, SARS, 진단, [키워드] 95% CI Accuracy acute infection adjust antibody CENTRAL CLIA Controlled controlled trials coronavirus disease Coronavirus disease 2019 COVID‐19 COVID‐19 Day determine diagnose Diagnosis diagnostic early infection eligibility criteria ELISA English language estimate evaluate for inclusion human participant ICA IgG IgM IgM and IgG Immunoglobulin immunosorbent Infection objective offer outbreak OVID percentage Result SARS‐CoV‐2 infection sensitivity Sensitivity and specificity Seroconversion Serological assay serological assays Serological testing serology significantly higher specificity symptom onset systematic review unique was performed [DOI] 10.1111/irv.12841 PMC 바로가기 [Article Type] Meta-Analysis
Serological Test to Determine Exposure to SARS-CoV-2: ELISA Based on the Receptor-Binding Domain of the Spike Protein (S-RBD N318-V510 ) Expressed in Escherichia coliCommunication Published on 2021-02-102022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] amino acid residue antibody Antigen approach Asymptomatic attachment Bacterial bacterial cultures complex COVID-19 COVID-19 testing Critical determine ELISA ELISAs Escherichia coli exposure to full-length spike protein Immunity individuals Infection massive N318-V510 peptide produced purified Receptor binding domain Result S-RBD SARS-CoV-2 SARS-CoV-2 antigen sera serological Serological testing spike Spike protein symptomatic Test the receptor-binding domain the SARS-CoV-2 the Spike virus [DOI] 10.3390/diagnostics11020271 PMC 바로가기 [Article Type] Communication
SARS-CoV-2 Seropositivity among Dental Staff and the Role of Aspirating Systems치과 직원의 SARS-CoV-2 혈청 양성 및 흡인 시스템의 역할COVID-19 Published on 2021-02-052022-09-10 Journal: JDR Clinical and Translational Research [Category] MERS, SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aerosol Aerosols Affect antibody Aspirating assistant atmosphere clinics coronavirus coronavirus disease dental dental health survey dental public health dentists detect exposure to Federation Follow-up HCW HCWs Health care health care workers HEPA HEPA filter high risk identify Immunoglobulin Immunoglobulin G Infection infection control Infectious disease management member once a week pandemic Patient Patient management Personal protective equipment Prevalence recommendation reported respiratory retrospective cohort study role SARS-CoV-2 SARS-COV-2 infection Serological testing Seropositivity Seroprevalence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Sex significantly higher staff System the SARS-CoV-2 Virology was used [DOI] 10.1177/2380084421993099 PMC 바로가기 [Article Type] COVID-19
SARS Coronavirus-2 Microneutralisation and Commercial Serological Assays Correlated Closely for Some but Not All Enzyme ImmunoassaysSARS 코로나바이러스-2 미세중화 및 상업적 혈청학적 분석은 일부 효소 면역분석에 대해 밀접한 상관관계가 있지만 전부는 아님Article Published on 2021-02-042022-09-01 Journal: Viruses [Category] MERS, 진단, 치료기술, 치료제, [키워드] anti-SARS-CoV-2 antibody Antigen antigens best binding antibodies binding antibody collected convalescent plasma correlated correlation COVID-19 COVID-19 pandemic cut-off detect determinant diagnostic Donor donors Elecsy enzyme enzyme immunoassays Euroimmun expressed FIVE greater Host immune response house IgA IgG immunoassay incidence Infection information laboratory-confirmed SARS-CoV-2 infection marker microneutralisation assay negative control Neutralising Antibodies neutralising antibody neutralising antibody titre neutralising antibody titres performance Post-infection Prevalence protective immunity provide Quantitative recovered patient recovered patients reported Research SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody Sensitivity and specificity sera Serological testing serology Spike protein targets vaccination were assessed [DOI] 10.3390/v13020247 PMC 바로가기 [Article Type] Article
Antibody dynamics to SARS-CoV-2 in asymptomatic COVID-19 infections무증상 COVID-19 감염에서 SARS-CoV-2에 대한 항체 역학Article Published on 2021-02-012022-09-12 Journal: Allergy [Category] MERS, SARS, 진단, [키워드] analyzed antibodies antibody Antibody dynamics Asymptomatic Asymptomatic carrier Asymptomatic COVID-19 asymptomatic individual asymptomatic infections Biomarker Combination condition controls COVID-19 demonstrated Detection sensitivity Diagnosis diagnostic did not produce dynamics of antibody Enrollment epidemiologically healthy individual Humoral immunity IgM and IgG IgM antibody IgM responses immunization strategies implication individual Infection infections knowledge Microarray microarray analysis mild patient N protein Neutralization assay neutralizing antibody nucleic acid pandemic peaked produced profile Protein proteome Pseudotyped virus public health raise recruited SARS-CoV-2 SARS-CoV-2 proteome screened sensitivity serological serological survey Serological testing serum significantly symptoms onset the NAT [DOI] 10.1111/all.14622 PMC 바로가기 [Article Type] Article