SARS-CoV-2 impairs the disassembly of stress granules and promotes ALS-associated amyloid aggregationSARS-CoV-2는 스트레스 과립의 분해를 손상시키고 ALS 관련 아밀로이드 응집을 촉진합니다Article Published on 2022-08-012022-09-11 Journal: Protein & Cell [Category] COVID19(2023년), SARS, 치료법, [키워드] ACE2 addition aggregation bind Cell cells cellular clearance experiment FUS Host host cells impair in vitro incorporation increased risk indicate infect Infection interactions Invasion mammalian cell mammalian cells Mutation N protein neurodegeneration NMR non-specific nucleocapsid nucleocapsid protein occur phase transition promote Protein Proteins reported SARS-CoV-2 SARS-COV-2 infection scenario stimulated Stress stress granule stress granules [DOI] 10.1007/s13238-022-00905-7 PMC 바로가기 [Article Type] Article
Connecting the dots between inflammatory cascades of obesity and COVID-19 in light of mortal consequences-a review치명적인 결과에 비추어 비만의 염증성 폭포와 COVID-19 사이의 점 연결 - 리뷰Review Published on 2022-08-012022-09-12 Journal: Environmental science and pollution research inter [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] ACE2 adipocyte adverse effects age angiotensin-converting enzyme 2 BMI body mass index cardiometabolic cascade children Coagulation combating complications consequence coronavirus disease correlation country COVID-19 Cytokine storm D-dimer determinant endothelial Epidemics Factors fatal disease greater immunological implicated individual individuals Inflammatory inflammatory cascade inflammatory parameters inflammatory pathology intensive care less Major molecular obese obesity organization pathology pathophysiological PBM pharmacological treatment RAAS reported resource risk Stress suggested therapeutic options therapy Treatment triggering vessel WAT. [DOI] 10.1007/s11356-022-21461-x PMC 바로가기 [Article Type] Review
Psychological outcomes of COVID-19 survivors at sixth months after diagnose: the role of kynurenine pathway metabolites in depression, anxiety, and stress진단 후 6개월째 COVID-19 생존자의 심리적 결과: 우울증, 불안 및 스트레스에서 키누레닌 경로 대사물의 역할Article Published on 2022-08-012022-09-11 Journal: Journal of neural transmission (Vienna, Austria : [Category] MERS, 바이오마커, [키워드] 3-hydroxykynurenine Activation Admission alteration Anxiety anxiety symptom Biomarker Biomarkers both groups center change coronavirus disease Coronavirus disease 2019 correlation COVID-19 DASS-21 Depression depressive Depressive symptoms exhibited Follow-up healthy control healthy controls Hospitalization illnesses immune response immunologic response in both groups increase in Inflammation initial initial assessment Kynurenic acid Kynurenine Kynurenine pathway leads life mechanism Mental metabolism metabolite outcome pandemic participant pathophysiology pathway plasma Plasma levels post-COVID-19 patient Post-COVID-19 patients predicted predictor Psychiatric psychiatric disorder Psychiatric disorders questionnaire reduction in Stress Stress Scale survivor Symptom target therapy to define TRP Tryptophan Viral viral infection viral infections virus was used with COVID-19 [DOI] 10.1007/s00702-022-02525-1 PMC 바로가기 [Article Type] Article
In-Silico targeting of SARS-CoV-2 NSP6 for drug and natural products repurposing의약품 및 천연물 용도 변경을 위한 SARS-CoV-2 NSP6의 In-Silico 표적화Article Published on 2022-08-012022-09-11 Journal: Virology [Category] COVID19(2023년), SARS, 신약개발, 치료제, [키워드] African binding binding site candidate Cell Compound compounds COVID-19 crystal structure database docking drug DrugBank Endoplasmic reticulum expansion FDA-approved drug inhibit inhibiting interactions involved molecular dynamics Molecular dynamics simulation molecular dynamics simulations natural natural products non-structural protein NSP6 pandemic product receptor SARS-CoV-2 SARS-CoV-2 replication screened sigma South Stress stress response targeting [DOI] 10.1016/j.virol.2022.06.008 PMC 바로가기 [Article Type] Article
Online cognitive behavioural therapy as a psychological vaccine against stress during the COVID-19 pandemic in pregnant women: A randomised controlled trialRandomized Controlled Trial Published on 2022-08-012022-10-05 Journal: Journal of psychiatric research [Category] Coronavirus, 임상, [키워드] affected Anxiety behavioural cognitive Cognitive behavioural therapy consequence contagious COVID-19 COVID-19 pandemic Depression Efficacy greater Intervention management pandemic participated Perceived stress Pregnancy pregnant pregnant women Psychological Psychopathology randomised randomised controlled trial Resilience Spain Stress Support group Symptom Symptoms therapy Treatment Trial Vaccine were assessed women [DOI] 10.1016/j.jpsychires.2022.07.016 PMC 바로가기 [Article Type] Randomized Controlled Trial
High-density EEG sleep correlates of cognitive and affective impairment at 12-month follow-up after COVID-19Research article Published on 2022-08-012022-10-05 Journal: Clinical neurophysiology : official journal of the [Category] 바이오마커, [키워드] acute COVID-19 affective alteration Beck Brain cognitive controls coronavirus disease-2019 correlated cortical COVID-19 discharge discharged Electroencephalography enrolled executive Follow-up high-density Hospital admission ICU impairment intensive care inventory life Long COVID-19 Nap Neuropsychological assessment objective participant Participants pathophysiology Pearson correlation Post-traumatic stress disorder Psychological PTSD Quality Result Significance slow Stress survivor [DOI] 10.1016/j.clinph.2022.05.017 [Article Type] Research article
Biologicals decrease psychological distress, anxiety and depression in severe asthma, despite Covid-19 pandemicArticle Published on 2022-08-012022-11-15 Journal: Respiratory medicine [Category] COVID19(2023년), SARS, 진단, [키워드] addition Affect Anxiety Asthma asthma patient Asthmatic patients benralizumab biologic Biological biological drug clinical disease Comorbidity decrease Depression depressive symptom disease drug evaluate female General population HADS Hypothesis independent males management Mental disorder mepolizumab monoclonal antibodies omalizumab pandemic parameters Patient patients treated Perceived stress Prevalence previous study problem PSS Psychiatric psychiatric disorder Psychological psychological disorders Psychological distress Quality of life reported Respiratory disease risk SARS-CoV-2 SARS-CoV-2 pandemic Severe asthma Stress treated Treatment [DOI] 10.1016/j.rmed.2022.106916 PMC 바로가기
Subjective mental well-being among higher education students in Finland during the first wave of COVID-19COVID-19의 첫 번째 물결 동안 핀란드의 고등 교육을 받은 학생들의 주관적인 정신적 웰빙Article Published on 2022-08-012022-09-11 Journal: Scandinavian Journal of Public Health [Category] Coronavirus, COVID19(2023년), SARS, 치료기술, [키워드] Adults age and gender COVID-19 COVID-19 outbreak COVID-19 pandemic COVID-19-related symptom COVID-19-related symptoms cross-sectional dataset decrease effect size Exploratory analysis Finland First wave Government higher education Increased Infection information initial investigated Mental mental health problem mental well-being moderate outbreak pandemic predicted provided question relationship Satisfaction scale Stress Subjective SWEMWBS two-way ANOVA was collected were used [DOI] 10.1177/14034948221075433 PMC 바로가기 [Article Type] Article
Stroke Family Caregiver Life Changes From the COVID-19 PandemicRandomized Controlled Trial Published on 2022-08-012022-10-05 Journal: International journal for equity in health [Category] 임상, [키워드] activities activity added affected Analysis analyzed approach assessment Care Caregiver change changes changes in conducted Consensus Controlled clinical trial COVID-19 COVID-19 pandemic Data analysis determine emotional family feasibility finding Healthcare provider indicated Internet life Masks negative negative and positive problem qualitative data Quantitative Randomized reduced resource response resulting scale selected social contact Stress stroke survivor telehealth unmet need [DOI] 10.1097/JNN.0000000000000654 PMC 바로가기 [Article Type] Randomized Controlled Trial
Resilience and its impact on the mental health of physiotherapists during the COVID-19 pandemic in São Paulo, BrazilArticle Published on 2022-08-012023-07-09 Journal: Journal of affective disorders [Category] COVID19(2023년), [키워드] Anxiety COVID-19 Depression physiotherapists Resilience Stress [DOI] 10.1016/j.jad.2022.05.049 PMC 바로가기