Crosstalk of TLR4, vascular NADPH oxidase, and COVID-19 in diabetes: What are the potential implications?Review article Published on 2021-08-012022-10-05 Journal: Vascular pharmacology [Category] SARS, 변종, [키워드] appear cardiovascular diseases contribute COVID-19 Critical Crosstalk diabetes Diabetic diabetic patients disrupt enzyme experimental evidence explain help higher risk Hypothesis implication Increased Interaction lack likelihood mechanism modulate NADPH NADPH oxidase oxidative stress pathophysiology patients with diabete progression receptor ROS severe coronavirus disease severe COVID-19 shown Signaling structures TLR4 Vascular vasculature [DOI] 10.1016/j.vph.2021.106879 [Article Type] Review article
Clinical and Pathophysiologic Spectrum of Neuro-COVIDNeuro-COVID의 임상 및 병태생리학적 스펙트럼Review Published on 2021-08-012022-09-11 Journal: Molecular neurobiology [Category] SARS, 치료제, [키워드] affected anticipated Brain Central and peripheral nervous system Central nervous system clinical COVID-19 COVID-19 patient determine disease Effects explain immune immune modulation Immune suppression Infection investigated less lung Lungs majority manifestation nervous system Neurological involvement neurologist occur outcome pathophysiology patients with COVID-19 peripheral nerve Peripheral nervous system recent finding respond SARS-CoV-2 SARS-CoV-2-infected patients side Side effects Skeletal muscle Spectrum structures virus [DOI] 10.1007/s12035-021-02383-0 PMC 바로가기 [Article Type] Review
Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egressArticle Published on 2021-07-302022-10-29 Journal: Nature Communications [Category] COVID-19, SARS, [키워드] approach Cell cells cellular changes component Critical Cryoelectron tomography cytopathic drastic event Evidence inactivated viruses Infection knowledge lack outbreak pandemic Pathogens pathway platform purified replicative SARS-CoV-2 SARS-COV-2 infection structures the SARS-CoV-2 tomography Transport unique Vero cells Viral RNA virus virus replication Virus spike Virus structures Volume X-ray [DOI] 10.1038/s41467-021-24887-y PMC 바로가기 [Article Type] Article
The Early Impacts of the COVID-19 Pandemic on Mental Health Facilities and Psychiatric ProfessionalsSystematic Review Published on 2021-07-292022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] article Care change conducted COVID-19 COVID-19 pandemic early stage Epidemic Evolution exclusion criteria Final first stage Health Health Facility Impact impacted IMPROVE Inclusion International literature review Mental disorder mental health mental health facilities mental health professional mental health professionals Novel coronavirus organizations pandemic professional Psychiatric psychiatry question Questionnaires recommendation reducing risk SARS-CoV-2 SARS-CoV-2 transmission selected structures systematic review while [DOI] 10.3390/ijerph18158034 PMC 바로가기 [Article Type] Systematic Review
Remote Management of Prosthodontic Emergencies in the Geriatric Population During the Pandemic Outbreak of COVID-19Medicine Published on 2021-07-282022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Complete coronavirus disease COVID-19 COVID-19 pandemic Emergency geriatric dentistry global pandemic individual Infection management outbreak pandemic Panic Partial Patient Population portable equipment prevalent prosthodontics recommendation remote structures susceptible Teledentistry [DOI] 10.3389/fmed.2021.648675 PMC 바로가기 [Article Type] Medicine
Diverse Effects of Exosomes on COVID-19: A Perspective of Progress From Transmission to Therapeutic DevelopmentsCovid-19에 대한 엑소 좀의 다양한 효과 : 전염에서 치료 적 발전으로의 진보의 관점Review Published on 2021-07-282022-08-31 Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus administration Anti-viral antiviral drug antiviral drugs approach causative agent cells combating Combination communication coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cytokine storm Defense develop development Diagnosis disease Effect ENhance Exosome Exosomes global pandemic Host immunomodulatory infected cells Infection intercellular Intervention lung injuries mesenchymal stem cell Mesenchymal stem cells mitochondrial Mitochondrial function modulate MSCs new strain new strain of coronavirus Numerous pathway Pathways Patient Perspective produced Progress promote reduce respiratory respiratory tract SARS-CoV-2 SARS-COV-2 infection secreted secretion severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 similarity Spread stem cell structures suppress the cytokine storm therapeutic agents Therapeutic benefit therapeutic benefits Therapeutics Therapies Transmission Treatment Treatment strategies treatment strategy uninfected cells Vaccine development Vaccines virus virus-infected cell virus-infected cells viruses with COVID-19 [DOI] 10.3389/fimmu.2021.716407 PMC 바로가기 [Article Type] Review
Determination of Ligand Binding Modes in Hydrated Viral Ion Channels to Foster Drug Design and Repositioning약물 디자인 및 재배치 촉진을 위한 수화된 바이러스 이온 채널의 리간드 결합 모드 결정Article Published on 2021-07-272022-09-10 Journal: Journal of Chemical Information and Modeling [Category] MERS, SARS, 신약개발, 치료제, [키워드] amantadine antiviral drug atomic resolution binding bridging interaction build candidate capture channel complex complex structure complexes COVID-19 pandemic derivative Determination determined by Diversity drug drug candidate drug design Drug discovery envelope protein experiment foster help hydrocarbon hydrophobic IMPROVE Influenza influenza A investigated Ion ion channel ion channels Ligand mechanism of action mode Numerous positioned protocol Region reliability repositioning resulting SARS-CoV-2 scratch Structure structures the SARS-CoV-2 transmembrane Undetermined water water molecules waters while [DOI] 10.1021/acs.jcim.1c00488 PMC 바로가기 [Article Type] Article
Projecting contact matrices in 177 geographical regions: An update and comparison with empirical data for the COVID-19 eraResearch Article Published on 2021-07-262022-10-28 Journal: PLoS Computational Biology [Category] COVID-19, SARS, [키워드] age Analysis Bank conducted Contact country Coverage COVID-19 COVID-19 pandemic demographic division Effect Effectiveness eight element Europe European country feature Geographic difference geographical locations geographical region group groups household household size Infection Infectious disease interact Interaction Intervention lack majority mathematical mathematical model Model outbreak Pathogens physical distancing Population Public health responses quantified risk similarity social contact Spread structures subgroup transmitted [DOI] 10.1371/journal.pcbi.1009098 PMC 바로가기 [Article Type] Research Article
Evolutionary Tracking of SARS-CoV-2 Genetic Variants Highlights an Intricate Balance of Stabilizing and Destabilizing MutationsSARS-CoV-2 유전자 변이체의 진화 추적은 안정화 돌연변이와 불안정화 돌연변이의 복잡한 균형을 강조합니다Research Article Published on 2021-07-202022-09-10 Journal: mBio [Category] MERS, SARS, 변종, 유전자 메커니즘, [키워드] A222V accounted addition analyzed B.1 balance catch caused COVID-19 pandemic D614G data set data sets database death Evolution Genome Genome sequences genomic information globe Infection mechanism Mutation mutations persistence Phylogenetic analysis Protein protein structures Q57H recorded S477N SARS-CoV-2 SARS-CoV-2 evolution selection pressure sequence stability structures T85I Therapeutics Vaccine variant variants Variation Viral viral mutation Viral mutations Viral protein Viral proteins [DOI] 10.1128/mBio.01188-21 PMC 바로가기 [Article Type] Research Article
Health and Gender Inequalities of the COVID-19 Pandemic: Adverse Impacts on Women’s Health, Wealth and Social WelfareGlobal Women's Health Published on 2021-07-202022-10-31 Journal: Frontiers in Global Women's Health [Category] COVID-19, [키워드] adopted Adverse adverse impact affected Care carried chronic disease Comorbidities COVID-19 COVID-19 pandemic demonstrated detrimental develop disease Diseases engage expected Gender global health Health highlight Impact increasingly independent individual inequality manifested men Musculoskeletal ontological Osteoarthritis Osteoporosis outcome outcomes pandemic public health public health measure Research rheumatoid arthritis SLE Spread structures systemic lupus erythematosus Systemic sclerosis Welfare women women's health [DOI] 10.3389/fgwh.2021.670310 PMC 바로가기 [Article Type] Global Women's Health