Model-Estimated Association Between Simulated US Elementary School–Related SARS-CoV-2 Transmission, Mitigation Interventions, and Vaccine Coverage Across Local Incidence Levels시뮬레이션된 미국 초등학교 관련 SARS-CoV-2 전파, 완화 중재 및 지역 발병 수준에 따른 백신 적용 범위 간의 모델 추정 연관성Research Published on 2022-02-142022-09-10 Journal: JAMA Network Open [Category] COVID19(2023년), MERS, SARS, 변종, 치료기술, [키워드] agent Alpha Alpha variant Analysis approach association assumption attack rate children Combination Community conducted consequence Coverage COVID-19 COVID-19 incidence decrease delta variant Effectiveness Elementary School estimate evaluated explicit exposure finding GRADE Importance incidence incidence rates increase increase in increasingly Infection infections Intensive less Level likelihood limits Local masking Masks measure Measures Mitigation moderate objective outcome participant per day Point Probability Quantitative reduced reducing reduction reduction in reflected Relevance representing Result risk SARS-CoV-2 SARS-CoV-2 transmission School secondary attack rate selected Sensitivity analyses setting substantial reduction substantial reductions the mean threshold thresholds Transmission transmissions vaccination Vaccine Ventilation wild-type virus with COVID-19 [DOI] 10.1001/jamanetworkopen.2021.47827 PMC 바로가기 [Article Type] Research
Comparison of Racial, Ethnic, and Geographic Location Diversity of Participants Enrolled in Clinic-Based vs 2 Remote COVID-19 Clinical Trials클리닉 기반과 2개의 원격 COVID-19 임상 시험에 등록한 참가자의 인종, 민족 및 지리적 위치 다양성 비교Research Published on 2022-02-142022-09-10 Journal: JAMA Network Open [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] access Accuracy age Alaska Analysis analytics analyzed Asian Baltimore black Boston Chicago clinical clinical trial clinical trials clinician cohort study collected component conducted convalescent plasma COVID COVID-19 COVID-19 infection COVID-19 pandemic criteria demographic data demographics Diversity enrolled Enrollment Evidence Expanded access Facebook female finding Follow-up Generalizability Geographic geographic location geographical location Google highest Hispanic Hydroxychloroquine Importance IMPROVE individual Infection Latinx location Los Angeles measure media nasal swab Native New New Orleans New York novel objective online advertising participant Participants Point Population populations Postexposure Prophylaxis public health Racial randomized clinical trial recruited recruitment Relevance remote reported Research Result SARS-CoV-2 Seattle setting Sex social media social media platforms study participant Study participants telehealth the mean Trial unique Washington were used white with COVID-19 [DOI] 10.1001/jamanetworkopen.2021.48325 PMC 바로가기 [Article Type] Research
Increased Circulating Cytokines Have a Role in COVID-19 Severity and Death With a More Pronounced Effect in Males: A Systematic Review and Meta-AnalysisPharmacology Published on 2022-02-142022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] 95% confidence interval acute respiratory syndrome article Asian caused circulating claimed coronavirus Coronavirus disease 2019 COVID-19 COVID-19 severity COVID-2019 cytokine Cytokines Cytokines storm death death group demonstrated driving Effect elevated Epidemic European Evidence Factor females groups high mortality identify IL-10 IL-17 IL-1β IL-4 IL-6 IL-8 Increased increased mortality Inflammatory cytokine interleukin-6 key factor male Meta-analysis Mortality much higher Necrosis non-survivor Patient patients potential risk predisposition receptor review risk of bia role SARS-CoV-2 screened searched Serum level severity Sex Sex bias significantly the mean TNF-α upregulation Web of Science were measured [DOI] 10.3389/fphar.2022.802228 PMC 바로가기 [Article Type] Pharmacology
Long-Term Persistence of Anti-SARS-COV-2 IgG Antibodies항-SARS-COV-2 IgG 항체의 장기간 지속성Article Published on 2022-02-122022-09-11 Journal: Current microbiology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 anti-SARS-CoV-2 anti-SARS-CoV-2 IgG antibody assays automated automated analyzer C-reactive protein collected Coronavirus-2 correlation decrease detectable determine Diseases evaluate evaluated Evidence evidence of FIVE Follow-up highest hospitalized patient IgG IgG and IgM IgG antibody IgM antibodies Infection lymphocyte Mild moderate neutrophil Neutrophil-to-lymphocyte ratio NLR no significant difference no significant differences onset of symptom Patient patients with COVID-19 PCR-confirmed persistence POS Real-time PCR recovered COVID-19 patient Recovered COVID-19 patients respiratory SARS-CoV-2 infections Serum level serum levels serum sample serum samples Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 Severity of disease significant differences significantly stability the immunoassay the mean titer [DOI] 10.1007/s00284-022-02800-0 PMC 바로가기 [Article Type] Article
Shorter serial intervals in SARS-CoV-2 cases with Omicron BA.1 variant compared with Delta variant, the Netherlands, 13 to 26 December 20212021년 12월 13일부터 26일까지 네덜란드 Delta 변종에 비해 Omicron BA.1 변종을 사용하는 SARS-CoV-2 사례에서 더 짧은 연속 간격Rapid Communication Published on 2022-02-102022-09-10 Journal: Eurosurveillance [Category] COVID19(2023년), MERS, SARS, 변종, [키워드] COVID-19 delta variant growth advantage Households immune evasion Incubation period indication interval Netherlands omicron Omicron variant S gene S gene target failure SARS-CoV-2 Serial interval the mean Transmissibility transmission pairs variant [DOI] 10.2807/1560-7917.ES.2022.27.6.2200042 PMC 바로가기 [Article Type] Rapid Communication
Work Performance, Mood and Sleep Alterations in Home Office Workers during the COVID-19 PandemicArticle Published on 2022-02-102022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] affected affecting age alteration assist benefit changed children COVID-19 COVID-19 pandemic cross-sectional Factors favor female female subject Government Health home office home office workers investigated irritability Local loneliness mood MOST pandemic parental participant performance questionnaire reported Satisfaction Sleep Sleep disturbance sleep quality Sociodemographic characteristics Support the mean variations was performed women work work perception worker [DOI] 10.3390/ijerph19041990 PMC 바로가기 [Article Type] Article
Patient Outcomes and Lessons Learned From Treating Patients With Severe COVID-19 at a Long-term Acute Care Hospital: Single-Center Retrospective StudyOriginal Paper Published on 2022-02-102022-10-30 Journal: JMIR Rehabilitation and Assistive Technologies [Category] COVID-19, [키워드] 95% CI acute COVID-19 Admission Admissions age Ambulation approach benefit Care Characteristics Clinical management Cohort complex Complication conducted COVID-19 COVID-19 cohort COVID-19 pandemic Critical Cutoff decrease discharge discharged electronic medical record evaluate female greater hospital impairment improvement lesson long-term acute care hospital majority male mechanically ventilated objective occupational therapy Odds ratio outcome pandemic Patient patients treated patients with COVID-19 Physical therapy positive positive correlation Post–COVID-19 postacute care proportion pulmonary rehabilitation resources respiratory therapy Result Retrospective analysis SARS-CoV-2 SARS-COV-2 infection severe COVID-19 shifting single-center speech therapy Speech-language pathology Stage subacute COVID-19 tested the mean treating Treatment United States [DOI] 10.2196/31502 PMC 바로가기 [Article Type] Original Paper
Charting the Information and Misinformation Landscape to Characterize Misinfodemics on Social Media: COVID-19 Infodemiology Study at a Planetary ScaleOriginal Paper Published on 2022-02-082022-10-30 Journal: Jmir Infodemiology [Category] COVID-19, [키워드] agency Analysis analyzed carried check Clustering collected contribute contributing to country COVID-19 domain driving Health help Hydroxychloroquine Hypothesis identify Infodemics infodemiology information Interaction landscape lockdown Measures mechanism media Medicines misinfodemics misinformation Novel coronavirus objective physical platform prevalent promoted Result SARS-CoV-2 scale social distancing measures social media social media platforms social networks Spread subset Surveillance susceptible the mean to define Topic Twitter while [DOI] 10.2196/32378 PMC 바로가기 [Article Type] Original Paper
Tracheostomy timing and clinical outcomes in ventilated COVID-19 patients: a systematic review and meta-analysisResearch Published on 2022-02-082022-11-01 Journal: Critical Care [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] 95% CI 95%CI association calculated Clinical outcome comparable conducted COVID-19 COVID-19 pandemic COVID-19 patient cumulative database defined Duration evaluate group ICU implication IMPROVE IMV intensive care unit Invasive mechanical ventilation less Meta-analysis mortality rate Odds ratio outcomes overall mortality Patient performed Primary outcome protocol random-effects model reductions in Registered reported Respiratory failure Result searched square supplementary material systematic review the mean tracheostomy Ventilated [DOI] 10.1186/s13054-022-03904-6 PMC 바로가기 [Article Type] Research
Co-circulation of SARS-CoV-2 Alpha and Gamma variants in Italy, February and March 20212021년 2월과 3월 이탈리아에서 SARS-CoV-2 알파 및 감마 변종 공동 유통Research Published on 2022-02-032022-09-10 Journal: Eurosurveillance [Category] COVID19(2023년), MERS, SARS, 변종, [키워드] Alpha Alpha variant assumed circulating clinical sample co-circulation competing Complete conducted cross-protection dominant Gamma genomic immune evasion Infection Italian territory Italy Lineage majority mathematical mathematical model National Prevalence proportion ranged remained replaced Result SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variant of concern Strains Surveillance the mean Transmissibility variant variants of SARS-CoV-2 viral strains VoC [DOI] 10.2807/1560-7917.ES.2022.27.5.2100429 PMC 바로가기 [Article Type] Research