Characterisation of a collection of Streptococcus pneumoniae isolates from patients suffering from acute exacerbations of chronic bronchitis: In vitro susceptibility to antibiotics and biofilm formation in relation to antibiotic efflux and serotypes/serogroups만성 기관지염의 급성 악화로 고통받는 환자들로부터 분리된 폐렴구균 집합체의 특성화: 항생제에 대한 시험관 내 감수성과 항생제 배출 및 혈청형/혈청군과 관련된 바이오필름 형성journal-article Published on 2014-09-012024-08-04 Journal: International Journal of Antimicrobial Agents [Category] 폐렴구균 감염증, [키워드] Acute exacerbations of chronic bronchitis (AECB) biofilm efflux serotype Streptococcus pneumoniae susceptibility [DOI] 10.1016/j.ijantimicag.2014.05.016 [Article Type] journal-article
High plasma levels of HLA-G are associated with low birth weight and with an increased risk of malaria in infancyHLA-G의 높은 혈장 수치는 저체중 출생과 유아기 말라리아 위험 증가와 관련이 있습니다.Research Published on 2014-08-122024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] HLA-G Low birth weight malaria Plasmodium falciparum susceptibility [DOI] 10.1186/1475-2875-13-312 PMC 바로가기 [Article Type] Research
An Essential Nonredundant Role for Mycobacterial DnaK in Native Protein Folding천연 단백질 폴딩에서 마이코박테리아 DnaK의 필수 비중복 역할Research Article Published on 2014-07-242022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] a minor absence accompanied accumulation aggregate antibiotic Bacterial pathogens bacterium Cell cell growth cells cellular chaperone chaperones characterized daughter cells Degradation denaturation Disruption domain E. coli Essential examined expand expression Factor foci genus growth heat Host Hsp70 identify include insoluble lack less life Loss membrane minor mycobacteria mycobacterial Mycobacterium Native organism paradigm Pathogens peptide peptides Prevent Protein protein folding Protein misfolding Proteins redundancy required role solubility stationary stationary phase Stress susceptibility synthases translation Trigger unique viability [DOI] 10.1371/journal.pgen.1004516 PMC 바로가기 [Article Type] Research Article
Differences in the tissue tropism to chicken oviduct epithelial cells between avian coronavirus IBV strains QX and B1648 are not related to the sialic acid binding properties of their spike proteinsResearch Published on 2014-06-142022-10-28 Journal: Veterinary Research [Category] Coronavirus, [키워드] analysed Asia avian coronavirus binding Cell characteristic Complete Culture difference disorders Efficiency epithelial cell epithelial cells Europe Genotype IBV infect Infection Infectious Bronchitis Virus kidney Kidney disease Occurrence organs oviduct pathogen pathogenicity permanent cell problem question reason reproductive S1 protein serotypes sialic acid Spike protein strain Strains sugar susceptibility the disease tissue tropism vaccination viruses [DOI] 10.1186/1297-9716-45-67 PMC 바로가기 [Article Type] Research
Risks for Infection in Patients With Asthma (or Other Atopic Conditions): Is Asthma More Than a Chronic Airway Disease?Article Published on 2014-06-122024-09-04 Journal: The Journal of Allergy and Clinical Immunology [Category] 대상포진, [키워드] Adaptive immunity allergic rhinitis Asthma atopic dermatitis Epidemiology immune dysfunction immune incompetence Infection Innate immunity phenotype risk susceptibility [DOI] 10.1016/j.jaci.2014.04.024 PMC 바로가기 [Article Type] Article
A current review of avian influenza in pigeons and doves (Columbidae)Review Published on 2014-06-042023-06-01 Journal: Veterinary microbiology [Category] 조류인플루엔자, [키워드] Avian Influenza Doves Pigeons susceptibility Transmission [DOI] 10.1016/j.vetmic.2014.02.042 [Article Type] Review
A HECT Ubiquitin-Protein Ligase as a Novel Candidate Gene for Altered Quinine and Quinidine Responses in Plasmodium falciparum플라스모듐 팔시파룸(Plasmodium falciparum)에서 변경된 퀴닌 및 퀴니딘 반응에 대한 새로운 후보 유전자로서의 HECT 유비퀴틴-단백질 리가제Research Article Published on 2014-05-152022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Altered Analysis antimalarial antimalarial drug Asia association candidate candidate gene changes in chromosome chromosome 13 complex conducted contribute contributing to cross cytotoxic activity defend demonstrated drug Efficacy experiment Factor Factors Genetic genetic screens genetic trait identify IMPROVE initial isolate Laboratory Ligase likelihood locus malaria malaria parasite moderate multiple allele multiple alleles mutated novel occur P. falciparum Plasmodium falciparum preservation progeny Quantitative quantitative trait locus quinidine Quinine response responsiveness segment sensitivity strain subset Surveillance susceptibility These data Treatment treatment failure ubiquitin ligase [DOI] 10.1371/journal.pgen.1004382 PMC 바로가기 [Article Type] Research Article
Antibody-dependent infection of human macrophages by severe acute respiratory syndrome coronavirusResearch Published on 2014-05-062022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] activated acute respiratory syndrome ADE Analysis Anti-viral antibodies antibody Antibody-dependent enhancement binding Cell cells chimeric competent consequence coronavirus cytoplasmic dependent on downstream elicited ENhance evaluate Fcγ receptor FcγR Fluorescence full-length Health heat-inactivated human coronavirus human macrophage human macrophages human monocyte-derived macrophage IgGs immune Immune cell immune complex Infection Infection route information Lentiviral particle Macrophage Microscopy molecular mechanism naïve observation Occurrence Pathogens performed polymerase chain Pseudotypes Public Quantitative receptor receptors Replication reported response Result risk RT-PCR SARS-CoV SARS-CoV vaccine serum shown Signaling signaling domain signaling pathway spike Support susceptibility transcriptase Trimers vaccination virus [DOI] 10.1186/1743-422X-11-82 PMC 바로가기 [Article Type] Research
High Risk Population Isolate Reveals Low Frequency Variants Predisposing to Intracranial Aneurysms고위험군 분리가 두개내 동맥류에 걸리기 쉬운 저주파 변이를 나타냅니다Research Article Published on 2014-01-302022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Aneurysm arteries Artery association Author balloon bleeding bottleneck events Brain Case-control cause compared complex complex diseases contribute Control controls develop different disease effect size effect sizes European population events explain explained Families Finn Finnish Finns FIVE fraction frequencies Frequency genetic background Genetic variant Genetic variation genotype imputation GWAS hemorrhage heritability identify incidence Inconclusive Intracranial intracranial aneurysms isolate isolates knowledge lead life-threatening loci locus low frequency MAF matched controls Netherland Netherlands Patient Population populations rare variant Rare variants related replicated rupture saccular stroke Study design Subarachnoid subarachnoid hemorrhage susceptibility tested utility variant variants [DOI] 10.1371/journal.pgen.1004134 PMC 바로가기 [Article Type] Research Article
A SYBR Green 1-based in vitro test of susceptibility of Ghanaian Plasmodium falciparum clinical isolates to a panel of anti-malarial drugs가나의 Plasmodium falciparum 임상 분리주에 대한 항말라리아 약물 패널에 대한 감수성을 평가하는 SYBR Green 1 기반의 인 비트로 테스트Research Published on 2013-12-172024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] in vitro inhibition isolates Plasmodium falciparum susceptibility [DOI] 10.1186/1475-2875-12-450 PMC 바로가기 [Article Type] Research