Streptococcus pneumoniae non-susceptibility and outpatient antimicrobial prescribing rates at the Alaska Native Medical Center알래스카 원주민 의료 센터에서의 폐렴구균 비감수성 및 외래환자 항균제 처방률Original Research Published on 2013-12-172024-08-23 Journal: International Journal of Circumpolar Health [Category] 폐렴구균 감염증, [키워드] Alaska Alaska Natives Antibiotic prescribing Antibiotic resistance invasive pneumococcal disease Streptococcus pneumoniae susceptibility [DOI] 10.3402/ijch.v72i0.22297 PMC 바로가기 [Article Type] Original Research
Differential Sensitivity of Bat Cells to Infection by Enveloped RNA Viruses: Coronaviruses, Paramyxoviruses, Filoviruses, and Influenza VirusesResearch Article Published on 2013-08-302022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] African aminopeptidase N analyzed angiotensin-converting enzyme 2 bat bovine Carollia Cell cell line cell lines cellular receptor coronavirus CoV different Efficiency enveloped RNA viruses Express Filoviridae Filovirus filoviruses gastroenteritis Host implication infect Infected Infection Influenza virus influenza viruses Isolation overcome pathogenic virus Protein pseudotype resistance to infection respiratory syncytial virus RNA SARS-coronavirus SARS-CoV SARS-related CoV Sendai virus Subtypes surface protein susceptibility Tadarida tested TGEV the S protein the Spike vesicular stomatitis virus virus VSV Yangochiroptera Yinpterochiroptera [DOI] 10.1371/journal.pone.0072942 PMC 바로가기 [Article Type] Research Article
Mixed-function oxidases and esterases associated with permethrin, deltamethrin and bendiocarb resistance in Anopheles gambiae s.l. in the south-north transect Benin, West Africa남부-북부 횡단선 베냉, 서아프리카에서 Anopheles gambiae s.l.의 퍼메트린, 델타메트린 및 벤디오카브 저항성과 관련된 혼합 기능 산화효소 및 에스터라제Research Published on 2013-08-062024-08-13 Journal: Parasites & Vectors [Category] 말라리아, [키워드] Anopheles gambiae CDC bioassay insecticide susceptibility Synergist [DOI] 10.1186/1756-3305-6-223 PMC 바로가기 [Article Type] Research
No Evidence for Hepatitis E Virus Genotype 3 Susceptibility in RatsLetter to the Editor Published on 2013-08-012023-06-09 Journal: Emerging Infectious Diseases [Category] E형 간염, Fulltext, [키워드] Genotype 3 hepatitis E virus immunodeficient nude rats rat HEV rat study RATs susceptibility viruses zoonoses [DOI] 10.3201/eid1908.130200 PMC 바로가기 [Article Type] Letter to the Editor
Mapping of PARK2 and PACRG Overlapping Regulatory Region Reveals LD Structure and Functional Variants in Association with Leprosy in Unrelated Indian Population GroupsPARK2 및 PACRG 겹치는 규제 영역의 매핑은 관련 없는 인도 인구 그룹의 나병과 관련된 LD 구조 및 기능적 변이를 나타냅니다.Research Article Published on 2013-07-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 한센병, [키워드] a major Affect assay association Author caused China clinical forms compared declined different disease disease pathogenesis Frequency Gene Gene Expression genetic background Genome genomic region granulomatous infection groups health problem heterogeneity Host human gene human genes impairment India Infection Infectious disease leprosy mapping Mycobacterium Mycobacterium leprae North organism other variant other variants PACRG Pathogenesis peripheral nerves Population population group population groups populations Prevalence provide public health reason for Region regulatory region replicated Replication reported reporter saturated several gene several genes significantly skin SNP SNPs Structure structures susceptibility the disease therapy upstream [DOI] 10.1371/journal.pgen.1003578 PMC 바로가기 [Article Type] Research Article
Differential Cell Line Susceptibility to the Emerging Novel Human Betacoronavirus 2c EMC/2012: Implications for Disease Pathogenesis and Clinical ManifestationArticle Published on 2013-06-012023-06-14 Journal: The Journal of Infectious Diseases [Category] MERS, [키워드] cell line coronavirus HCoV-EMC novel susceptibility [DOI] 10.1093/infdis/jit123 PMC 바로가기
Arabidopsis thaliana RESISTANCE TO FUSARIUM OXYSPORUM 2 Implicates Tyrosine-Sulfated Peptide Signaling in Susceptibility and Resistance to Root InfectionArabidopsis thaliana FUSARIUM OXYSPORUM 2에 대한 내성은 뿌리 감염에 대한 감수성과 내성에 티로신-황산염 신호 전달을 의미합니다Research Article Published on 2013-05-232022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] acting Affect Arabidopsis thaliana Diversity downregulate effector explain expression Extracellular Fusarium Gene Genes host immunity induce Infection inhibit lethal leucine loci locus mutant mutants negative feedback pathogen-specific peptide plant promote Protein provide QTLs Quantitative receptor Regulation related relative susceptibility replaced resistance root Signaling Support suppresse susceptibility traits transgenic tyrosine Vascular while [DOI] 10.1371/journal.pgen.1003525 PMC 바로가기 [Article Type] Research Article
Comparison of the standard WHO susceptibility tests and the CDC bottle bioassay for the determination of insecticide susceptibility in malaria vectors and their correlation with biochemical and molecular biology assays in Benin, West Africa말라리아 매개체의 살충제 감수성 결정에 대한 표준 WHO 감수성 테스트와 CDC 병 생물학적 시험의 비교 및 이들의 생화학 및 분자 생물학 분석과의 상관관계, 베냉, 서아프리카Research Published on 2013-05-202024-08-13 Journal: Parasites & Vectors [Category] 말라리아, [키워드] Anopheles gambiae CDC bioassay insecticide susceptibility Synergist WHO bioassay [DOI] 10.1186/1756-3305-6-147 PMC 바로가기 [Article Type] Research
Differentiated phenotypes of primary murine alveolar epithelial cells and their susceptibility to infection by respiratory virusesArticle Published on 2013-04-292022-11-01 Journal: Virus research [Category] Coronavirus, 신종인플루엔자, [키워드] activating alveolar cell alveolar epithelial cell alveolar epithelial cells ATII Cell cell type cells contribute coronavirus correlated Critical Culture cytokine cytokine expression cytokine response Cytokines determine determined different disease severity epithelial cell exhibited Express expression Factor H1N1 Host IAV identify IL-1β immune responses in vitro model in vivo increased expression Infected Infection influenza A influenza A virus lung Lungs maintain Mouse-adapted SARS-coronavirus mouse-adapted SARS-CoV mRNA murine murine coronavirus murine model Pathogenesis pathology phenotype quantified respiratory viral infection respiratory virus respiratory viruses response robust SARS-CoV severe spread to susceptibility susceptible target type I Type I pneumocyte Type II pneumocyte v2163 viral infection viral infections viral pathogenesis virus viruses while [DOI] 10.1016/j.virusres.2013.04.008 PMC 바로가기 [Article Type] Article
Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases기능성 IL6R 358Ala 대립유전자는 전통적인 IL-6 수용체 신호 전달을 손상시키고 다양한 염증성 질환의 위험에 영향을 미칩니다Research Article Published on 2013-04-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] 358Ala Abdominal aortic aneurysm affecting allele analyzed aortic aneurysm approach Arthritis Asp358Ala association Asthma Atrial fibrillation Author balance benefit Cambridge BioResource causal variant CD4+ T cell CD4+ T cells CHD Chronic diseases circulating cleavage clinical trial clinical trials common diseases complex complex diseases Concentration Control copy Coronary heart disease Critical cytokine diabete diabetes etiology Evidence expression functional Genetic genetic association Genetic variation heart disease human disease identify IL-6 IL-6 receptor IL-6 signaling IL-6R IL-6R signaling IL-6R signaling pathway IL6R Immune cell immune cells impairment implicated implication increase increase in independent Inflammatory Inflammatory responses influence interleukin interleukin-6 isoform mechanism membrane-bound molecular mechanism monocyte Monocytes mononuclear cell mononuclear cells Non-synonymous nucleotide Patient PBMCs Peripheral blood Peripheral blood mononuclear cells Phosphorylation polymorphism Population protein level protein levels RA reduce reduced reduction regulated Regulation rheumatoid arthritis risk rs2228145 Signaling sIL-6R single nucleotide Single nucleotide polymorphism soluble IL-6R Stat1 STAT3 Stimulation suggested surface expression surface receptor susceptibility T cells T1D therapeutic intervention therapy These data Transcription transcription factor transcription factors translate Treatment response Type 1 diabetes variant Variation Volunteer [DOI] 10.1371/journal.pgen.1003444 PMC 바로가기 [Article Type] Research Article