Prevalence and predictors of death and severe disease in patients hospitalized due to COVID-19: A comprehensive systematic review and meta-analysis of 77 studies and 38,000 patientsCOVID-19로 인해 입원한 환자의 사망 및 중증 질환의 유병률 및 예측인자: 77건의 연구 및 38,000명의 환자에 대한 포괄적인 체계적 검토 및 메타 분석Research Article Published on 2020-12-072022-08-13 Journal: PLoS ONE [Category] COVID-19, Medicine and Health Sciences, MERS, SARS, [키워드] 95% CI adjusted adverse outcome adverse outcomes analyzed association China Chronic kidney disease chronic liver disease CKD CLD Comorbidities confidence interval COPD COVID-19 COVID-19 patient death determine diabete diabetes died disease Disease progression Europe fatality Health health screening heart disease heterogeneity Hospitalized hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient hospitalized patients hypertension Inclusion inclusion criteria individual Infection Kidney disease male males Meta-analysis morbidity morbidity and mortality objective observational studies observational study Patient patients hospitalized predictor Prevalence Public reduce Relative risk Result risk risk factor Risk factors searched severe disease smoking susceptibility susceptibility to infection systematic review Web of Science [DOI] 10.1371/journal.pone.0243191 PMC 바로가기 [Article Type] Research Article
The role of Frailty on Adverse Outcomes Among Older Patients with COVID-19고령 COVID-19 환자의 역효과에 대한 노쇠의 역할Article Published on 2020-12-012022-09-11 Journal: The Journal of Infection [Category] SARS, 치료기술, [키워드] 95% CI adjusted odds ratio adjusted odds ratios Adverse adverse outcome adverse outcomes characterized clinician cohort study conducted COVID-19 COVID-19 patient defined discharged effective frailty group health systems Healthcare provider healthcare providers highest hospital Hospitalized hospitalized patient in-hospital mortality in-hospital mortality rate in-hospital mortality rates infected with COVID-19 management mortality rates Observed older population Patient Primary outcome provide risk therapeutic Turkey were excluded with COVID-19 [DOI] 10.1016/j.jinf.2020.09.029 PMC 바로가기 [Article Type] Article
Liver Injury in Liver Transplant Recipients With Coronavirus Disease 2019 (COVID-19): U.S. Multicenter ExperienceObservational Study Published on 2020-12-012022-10-05 Journal: Hepatology (Baltimore, Md.) [Category] SARS, 임상, [키워드] 95% CI 95% confidence interval Acute liver injury adverse outcomes age alanine aminotransferase ALT antibiotic use chronic liver disease conducted Coronavirus disease 2019 COVID-19 experience help Hispanic Hispanic ethnicity Hospitalized ICU ICU admission Immunosuppression incidence Injury intensive care interquartile range limit liver enzyme Liver injury Liver transplantation male moderate Mortality multicenter Odds ratio Patient Prevalence recipient recipients risk significantly syndrome the United State Transplant ULN variable with COVID-19 [DOI] 10.1002/hep.31574 PMC 바로가기 [Article Type] Observational Study
Pregnancy Outcomes Among Women With and Without Severe Acute Respiratory Syndrome Coronavirus 2 Infection중증 급성 호흡기 증후군 코로나바이러스 2 감염 유무에 관계없이 여성의 임신 결과Research Published on 2020-11-192022-09-12 Journal: JAMA Network Open [Category] SARS, 진단, [키워드] 95% CI Abnormalities abnormality acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adverse outcome adverse outcomes age Analysis Asymptomatic black blinded body mass body mass index Care Clinical management Cohort cohort study Composite conducted coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 Critical described diabete diabetes Disease progression disease severity during pregnancy emergency department evaluate exposure Features fetal fetal heart rate finding Frequency gestation Health Health care Health care system heart rate Hispanic hospital Hospital admission Hospitalization hospitalizations Hospitalized Illness severity Importance indication Infant Infants Infection initial Maternal maternity hospital measure Mild Neonatal Neonatal infection no difference no differences nonpregnant objective Observational cohort study occur occurred outcome outcomes parity participant pathologic pathologist pathology placental Point positive preeclampsia Pregnancy pregnant women prenatal Preterm birth Primary outcome Relative risk Relevance respiratory Result risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity SARS-CoV-2 testing SARS-CoV-2–positive setting severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe or critical illness symptomatic System tested Transmission white widespread women [DOI] 10.1001/jamanetworkopen.2020.29256 PMC 바로가기 [Article Type] Research
Elevated markers of thrombo-inflammatory activation predict outcome in patients with cardiovascular comorbidities and COVID-19 disease: insights from the LEOSS registry혈전-염증 활성화의 상승된 마커는 심혈관 동반 질환 및 COVID-19 질병이 있는 환자의 결과를 예측합니다: LEOSS 레지스트리의 통찰력Original Paper Published on 2020-11-192022-09-11 Journal: Clinical Research in Cardiology [Category] 바이오마커, [키워드] 95% CI Abstract Activation adverse outcome adverse outcomes Analysis analyzed Anti-inflammatory therapy anticoagulation calculated cardiovascular comorbidities cardiovascular comorbidity cardiovascular disease clinical Clinical course Clinical data Clinical stage Coagulation collected COVID-19 COVID-19 disease COVID-19 in patient CRP elevated enrolled European IL-6 IMPROVE Infection Inflammation Laboratory marker Mortality Multivariate analysis multivariate regression analysis myocardial injury open outcome Patient patients with COVID-19 patients with SARS-CoV-2 predict predictor regression analysis SARS-COV-2 infection SARS-CoV‑2 significantly higher specific biomarker specific biomarkers starting supplementary material survey the disease troponin [DOI] 10.1007/s00392-020-01769-9 PMC 바로가기 [Article Type] Original Paper
Prognostic Impact of Prior Heart Failure in Patients Hospitalized With COVID-19COVID-19로 입원한 환자의 이전 심부전의 예후 영향Article Published on 2020-11-172022-09-11 Journal: Journal of the American College of Cardiology [Category] Coronavirus, 변종, 유전자 메커니즘, [키워드] 95% confidence interval adjusted adjusted odds ratio adverse outcome adverse outcomes age aldosterone angiotensin Characteristics classification clinical Clinical characteristics conducted coronavirus coronavirus disease coronavirus disease-2019 COVID-19 described Ejection fraction Electronic health records etiology failure functional heart heart failure higher risk history hospital Hospitalized Impact in-hospital mortality increased risk inhibitor intensive care intensive care unit left ventricular ejection fraction LVEF mechanical ventilation Mortality Mount Sinai New York City Odds ratio outcome Patient patients hospitalized Renin renin-angiotensin-aldosterone system renin-angiotensin-aldosterone system inhibitor. Retrospective analysis revision System ventricular ventricular ejection with COVID-19 women [DOI] 10.1016/j.jacc.2020.09.549 PMC 바로가기 [Article Type] Article
Mortality and other adverse outcomes in patients with type 2 diabetes mellitus admitted for COVID-19 in association with glucose-lowering drugs: a nationwide cohort studyResearch Article Published on 2020-11-162022-10-28 Journal: BMC Medicine [Category] COVID-19, SARS, [키워드] 1:1 accompany Admission adverse outcome adverse outcomes association Characteristics cohort of patient cohort study Combination Coronavirus disease 2019 COVID-19 COVID-19 patient diabete Dipeptidyl peptidase-4 drugs evaluate evaluated Evidence Glucose-lowering drug hospital Hospital stay ICU admission In-hospital in-hospital complication In-hospital death information inhibitor inhibitors insulin intensive care internal invasive Limited Logistic regression logit mechanical ventilation monotherapy Mortality multicenter Non-invasive outcome Patient patients with COVID-19 propensity score matching Prospective Study registry Result Sample size selected Society Spain Spanish standardized mean difference study outcomes Treatment type 2 diabete Type 2 diabetes mellitus were used [DOI] 10.1186/s12916-020-01832-2 PMC 바로가기 [Article Type] Research Article
Association of cardiac biomarkers and comorbidities with increased mortality, severity, and cardiac injury in COVID-19 patients: A meta-regression and decision tree analysisCOVID-19 환자의 사망률, 중증도 및 심장 손상이 증가한 심장 바이오마커 및 동반 질환의 연관성: 메타 회귀 및 의사 결정 트리 분석Meta-Analysis Published on 2020-11-012022-09-11 Journal: Journal of medical virology [Category] 바이오마커, 진단, [키워드] 95% CI 95% confidence interval advanced age adverse outcome adverse outcomes Analysis applied aspartate Aspartate aminotransferase assessment association AST best Biomarker cardiac injury cardiac marker Cardiac markers cardiac troponin cardiovascular disease cardiovascular diseases cardiovascular system characteristic CIs clinical feature Comorbidity coronavirus coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 severity Cutoff Decision tree Deleterious develop elevated highest IMPROVE increased mortality Injury Laboratory lead Meta-analysis meta-regression Mortality mortality rate myocardial injury Odds ratio outcome outcomes Patient patients with COVID-19 predict prognostic receiver operating characteristic risk SARS-CoV-2 severity SMD standardized mean difference therapeutic approaches threshold troponin I [DOI] 10.1002/jmv.26166 PMC 바로가기 [Article Type] Meta-Analysis
Delirium and Adverse Outcomes in Hospitalized Patients with COVID-19Observational Study Published on 2020-11-012022-10-05 Journal: Journal of the American Geriatrics Society [Category] 임상, [키워드] 95% confidence interval adjusted adjusted odds ratio Admission Adults Adverse adverse outcome adverse outcomes age Aged albumin assessments association baseline Brazil C-reactive protein Care change clinical history clinical information clinician COVID-19 COVID-19 patients D-dimer death delirium electronic medical record glomerular filtration rate hospital Hospitalized hospitalized patient identification In-hospital death in-hospital mortality instrument intensive care laboratory biomarker longitudinal Lymphocyte count Mental MONITOR multivariable analysis Occurrence Older outcome pandemic participant Patient Patient care patients physician Prognosis reached Severe case severity and prognosis Sex Tertiary university hospital ventilator vital signs with COVID-19 [DOI] 10.1111/jgs.16803 PMC 바로가기 [Article Type] Observational Study
Coagulation biomarkers are independent predictors of increased oxygen requirements in COVID-19응고 바이오마커는 COVID-19에서 증가된 산소 요구량에 대한 독립적인 예측자입니다.Article Published on 2020-11-012022-09-11 Journal: Journal of thrombosis and haemostasis : JTH [Category] 바이오마커, [키워드] 95% CI 95% confidence interval activated Admission adult COVID-19 patient adverse outcome adverse outcomes age Analysis Antigen association baseline Biomarker Biomarkers BMI body mass body mass index C-reactive protein Coagulation Comorbidity confounder contribute COVID-19 COVID-19 patients CRP D-dimer D-dimers death diabetes factor VIII fibrinogen Follow-up FVIII hazard ratio hypercoagulability hypertension independent predictor leucocytes metabolic syndrome outcomes oxygen Oxygen requirement Oxygen requirements partial thromboplastin time Pathogenesis plasma Platelet platelet-poor plasma Platelets Pneumonia Predictive Prothrombin time regression analysis risk SARS-CoV-2 pneumonia SARS-CoV2 Sex significantly subdistribution syndrome THROMBOPLASTIN thrombosis univariable von Willebrand factor vWF [DOI] 10.1111/jth.15067 PMC 바로가기 [Article Type] Article