AST – Page 17 – Communicable Diseases Research

COVID-19-Induced Hepatic Injury: A Systematic Review and Meta-Analysis

Internal Medicine

Published on 2020-10-132022-10-31
Journal: Cureus [Category] COVID-19,

Clinical and laboratory data, radiological structured report findings and quantitative evaluation of lung involvement on baseline chest CT in COVID-19 patients to predict prognosis

임상 및 실험실 데이터, 방사선학적 구조화된 보고서 결과 및 예후 예측을 위한 COVID-19 환자의 기준 흉부 CT에서 폐 침범의 정량적 평가

Chest Radiology

Published on 2020-10-122022-09-01
Journal: La Radiologia Medica [Category] MERS, SARS, 진단,

[키워드] Accuracy addition Admission age ALT artificial intelligence AST azotemia baseline Bilirubin calculate Chain Reaction Chest CT chest CT examination Chest CT image Chest CT images clinical Combination Comorbidities Comorbidity condition Consensus consolidation consolidations COVID-19 COVID-19 disease COVID-19 patient COVID-19 pneumonia creatinine critical condition CRP CT finding CT findings D-dimer died dimer discharged disease distribution emphysema evaluate evaluated GGO Ground-glass opacities ground-glass opacity healthy highest Hospitalized Hounsfield unit independent predictor independent predictors Laboratory laboratory data laboratory findings LDH leukocyte lobe lung lung involvement lung parenchyma Lungs material multivariate regression analysis Neutrophils not affect objective outcome Patient patients patients hospitalized patients with COVID-19 performed Pneumonia polymerase chain polymerase chain reaction predict Prognosis pulmonary disease quantification Quantitative R 2 radiological Radiologists regression analysis Regression model regression models Result reverse transcription RT-PCR scoring system sensitivity severity Severity Score significantly higher significantly lower specificity SpO2 statistically significant statistically significant difference suspicious COVID-19 the patient Thoracic three group three groups troponin Viral viral infection Volume was obtained was performed women
[DOI] 10.1007/s11547-020-01293-w PMC 바로가기 [Article Type] Chest Radiology

High aspartate aminotransferase to alanine aminotransferase ratio on admission as risk factor for poor prognosis in COVID-19 patients

Article

Published on 2020-10-052022-10-04
Journal: Scientific Reports [Category] MERS, 진단,

Life-saving effect of convalescent plasma treatment in covid-19 disease: Clinical trial from eastern Anatolia

Clinical Trial

Published on 2020-10-012022-10-04
Journal: Transfusion and apheresis science : official journ [Category] 임상, 치료법,

Abnormal Liver Tests in COVID-19: A Retrospective Observational Cohort Study of 1,827 Patients in a Major U.S. Hospital Network

Observational Study

Published on 2020-10-012022-10-05
Journal: Hepatology (Baltimore, Md.) [Category] SARS, 임상,

[키워드] abnormality acute respiratory distress acute respiratory syndrome Admission age alanine aminotransferase albumin alkaline phosphatase ALP ALT analyzed Aspartate aminotransferase association AST baseline body mass index caused Characteristics clinical Clinical outcome clinical outcomes conducted coronavirus COVID-19 death Diabetes Mellitus disease Elevation Hospitalization Hospitalized hospitalized patient Hydroxychloroquine ICU admission Injury intensive care limit liver liver test liver transaminase Major Male sex mechanical ventilation morbidity and mortality Most patient multiorgan failure Multivariate analysis network occur outcome pandemic Patient Pneumonia proportion Remdesivir reported retrospective cohort study severe COVID-19 syndrome System Test Tocilizumab total bilirubin Treatment ULN virus with COVID-19
[DOI] 10.1002/hep.31487 PMC 바로가기 [Article Type] Observational Study

Can elevated concentrations of ALT and AST predict the risk of ‘recurrence’ of COVID-19?

Original Paper

Published on 2020-09-212022-11-01
Journal: Epidemiology and Infection [Category] COVID-19,

Subcutaneous Sarilumab in hospitalised patients with moderate-severe COVID-19 infection compared to the standard of care (SARCOVID): a structured summary of a study protocol for a randomised controlled trial

Letter

Published on 2020-09-092022-10-29
Journal: Trials [Category] Coronavirus, SARS,

[키워드] 24 hour 7-point ordinal scale absence addition administration Admission ALT anticipated assigned AST baseline biological parameters candidate Care clinical Clinical research clinical status clinical trial clinician Comorbidity conditions Control control arm control group Coronavirus infections Council COVID 19 COVID-19 COVID-19 infection criteria current D-dimer Day death rate decrease discharge dissemination dose drug Duration early stage Efficacy element ELISA enrolment EudraCT European evaluate exclusion criteria exploratory extracorporeal membrane oxygenation Frame harmonization hospitalisation hospitalised hospitalised patient hyperinflammatory status hypersensitivity Hypothesis identify IL-6 IL-6 levels IL-6 receptor inhibitors IL-6R In-hospital incidence Inclusion inclusion criteria independent Infection Informed inhibitor interstitial pneumonia Intervention intervention group intestinal perforation Invasive mechanical ventilation investigator investigator-initiated lactation Local marker measure mechanical ventilation moderate moderate-severe neutrophil count Non-invasive non-invasive ventilation number number of death objective Open label trial outbreak outcome oxygen Oxygenation pandemic participant pathogen patients treated performed Platelet Pneumonia positive positive RT-PCR Positive test Prednisone Presence Prevent progression protocol random randomisation randomised randomised controlled trial receive recruited recruitment Registered reported requiring supplemental oxygen responsible routine clinical practice RT-PCR SAEs Sample size sarilumab SARS-CoV-2 SARS-COV-2 infection score Sepsis Serious Adverse Event serum Severe COVID-19 Infection single center single dose Spain Standard Standard of care status Study protocol Subcutaneous subcutaneous injection the patient therapy treated Treatment treatment arm treatment with tocilizumab Trial ULN union unit verbal website
[DOI] 10.1186/s13063-020-04588-5 PMC 바로가기 [Article Type] Letter

Clinical and laboratory features of COVID-19: Predictors of severe prognosis

Article

Published on 2020-09-092022-11-01
Journal: International immunopharmacology [Category] COVID-19,

[키워드] abnormality Admission albumin aspartate amino transferase AST AUC Cell clinical Coagulation Comorbidity comprehensive analysis Coronavirus disease 2019 COVID-19 COVID-19 patients creatinine Critical CRP cut-off value D-dimer decrease diagnosed with COVID-19 Effect ferritin Follow-up hemoglobin highest hospital hospitalized patient ICU ICU care ICU patient identify include increase Infection intensive care Laboratory laboratory data laboratory feature laboratory parameter lactate dehydrogenase LDH leucocytes logistic regression model Lymphocytes management median medical record MLR neutrophil–lymphocyte ratio Neutrophils NLR non-critically ill patient Odds ratio Older parameter pathophysiology Patient predict predictor Prognosis Protein required Result risk ROC analysis Severe patient severe SARS-CoV-2 single-center Spread Support the disease the patient to define urea variable with COVID-19 Wuhan, China
[DOI] 10.1016/j.intimp.2020.106950 PMC 바로가기 [Article Type] Article

SARS-CoV-2 Infection Induces a Dual Response in Liver Function Tests: Association with Mortality during Hospitalization

Article

Published on 2020-09-042022-10-28
Journal: Biomedicines [Category] COVID-19,

[키워드] abnormality acute respiratory syndrome adjusted Admission age and sex alanine aminotransferase albumin levels alkaline phosphatase ALP ALT Aspartate aminotransferase associations AST Biochemistry change conducted coronavirus COVID-19 defined determine died discharged elevated evaluated ferritin Follow-up follow-up period function hepatic biomarkers Hospitalization hospitalized patients increase intensive care Laboratory limit liver Liver damage liver function tests mixed models normality Patient prevalent reduced respiratory complication response Retrospective study SARS-CoV-2 single-center subsequent Surveillance survival trajectory
[DOI] 10.3390/biomedicines8090328 PMC 바로가기 [Article Type] Article

Gastrointestinal Symptoms and Elevation in Liver Enzymes in COVID-19 Infection: A Systematic Review and Meta-Analysis

Internal Medicine

Published on 2020-08-242022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] 95% CI addition alanine aminotransferase albumin ALT article Aspartate aminotransferase AST calculated Corona virus COVID 19 COVID-19 COVID-19 patient diarrhea elevated Elevation fixed Gastrointestinal Gastrointestinal symptom General population Health Infection lft - liver function tests liver enzyme low albumin mean difference Meta-analysis nausea nausea and vomiting nausea/vomiting non-severe patient pandemic Patient patients with COVID-19 Platelet proportion random effect Result review severe COVID-19 severe disease Severe patient severe patients systematic review virus infection vomiting Wuhan, China
[DOI] 10.7759/cureus.9999 PMC 바로가기 [Article Type] Internal Medicine