Estimating the herd immunity threshold by accounting for the hidden asymptomatics using a COVID-19 specific modelResearch Article Published on 2020-12-162022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] asymptomatic patient asymptomatic patients country COVID-19 epidemiological data Herd immunity threshold hidden Immunity Infection infections Migration parameter Quantitative real-world data resulting shown Spread symptomatic patient [DOI] 10.1371/journal.pone.0242132 PMC 바로가기 [Article Type] Research Article
Transmissibility of COVID-19 depends on the viral load around onset in adult and symptomatic patientsCOVID-19의 전염성은 성인 및 증상이 있는 환자의 발병 주변 바이러스 부하에 따라 다릅니다.Clinical Trial Published on 2020-12-092022-08-13 Journal: PLoS ONE [Category] MERS, SARS, 임상, 진단, [키워드] analysed Analysis approach asymptomatic patient asymptomatic patients Case-control children Clinical data contribute coronavirus disease Coronavirus disease 2019 Course COVID-19 help household contacts in some index initial instances laboratory-confirmed log median Median viral load nasopharyngeal viral load non-linear regression Novel coronavirus novel coronavirus disease objective Patient patients patients with COVID-19 Result secondary transmission significantly higher symptomatic symptomatic and asymptomatic symptomatic patient Symptomatic patients the disease Toyama Transmission transmitted university Viral Viral load viral loads were assessed were measured [DOI] 10.1371/journal.pone.0243597 PMC 바로가기 [Article Type] Clinical Trial
Molecular epidemiology of SARS-CoV-2 clusters caused by asymptomatic cases in Anhui Province, China중국 안후이성 무증상 감염자에 의한 SARS-CoV-2 집단의 분자역학Research Article Published on 2020-12-072022-09-10 Journal: BMC Infectious Diseases [Category] MERS, SARS, 유전자 메커니즘, [키워드] addition analyzed Asymptomatic carrier Asymptomatic carriers Asymptomatic case Asymptomatic cases asymptomatic infection asymptomatic infections asymptomatic patient asymptomatic patients caused characterized China close contact Cluster Clusters Complete conducted Contact contribute coronavirus COVID-19 disease disease transmission emerging disease Epidemic epidemiological Epidemiological investigation Epidemiology infectiousness information initial investigated Novel coronavirus nucleotide outbreak pandemic patients Propagation provided Result SARS-CoV-2 sequenced single nucleotide variation spike gene spike gene sequence Spread Strains Transmission virus viruses widespread Wuhan [DOI] 10.1186/s12879-020-05612-4 PMC 바로가기 [Article Type] Research Article
Epidemiological and viral features of a cohort of SARS-CoV-2 symptomatic and asymptomatic individuals in an area of the Colombian Caribbean콜롬비아 카리브해 지역의 SARS-CoV-2 증상 및 무증상 개인 코호트의 역학 및 바이러스 특징Short Report Published on 2020-12-072022-09-10 Journal: Annals of Clinical Microbiology and Antimicrobials [Category] MERS, SARS, 치료기술, 치료제, [키워드] 2019-nCoV assay acute respiratory syndrome acute respiratory syndrome coronavirus age approach arthralgia Asymptomatic asymptomatic individual asymptomatic infections asymptomatic patient asymptomatic patients average average age caused Chain Reaction clinical sample co-morbidities Cohort Communicable disease control Contact Córdoba coronavirus coronavirus 2 Coronavirus infections cough country COVID-19 Critical deaths Department detect develop Dilution Environment and public health feature Fever group Health hospital implication individual individuals Infection Laboratory lack lysis buffer molecular morbidities MOST multiplex nasopharyngeal sample Nasopharyngeal samples objective Occurrence odynophagia pandemic pandemic disease patients required hospitalization PCR assay polymerase chain polymerase chain reaction positive positive control Pre symptomatic disease presymptomatic proportion Public Public health intervention Public health interventions quantification real-time PCR assay reduced regions reported respiratory Result reverse transcription reverse transcription real-time polymerase chain reaction RNA RNA copies RNA copy RT-qPCR SARS-CoV-2 SARS-CoV-2 infected individual SARS-CoV-2 infected individuals SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly higher socio-demographic South America standard curve symptomatic symptomatic and asymptomatic symptomatic patient Symptomatic patients Symptoms target gene Target genes tested the patient Transmission Viral viral load quantification was done were used [DOI] 10.1186/s12941-020-00397-5 PMC 바로가기 [Article Type] Short Report
Detection of severe acute respiratory syndrome coronavirus 2 in nasopharynx according to clinical phenotype of affected patients환자의 임상적 표현형에 따른 비인두의 중증급성호흡기증후군 코로나바이러스 2 검출Article Published on 2020-12-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] SARS, 치료기술, [키워드] activities acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted affected analysed asymptomatic individual Asymptomatic individuals asymptomatic patient asymptomatic patients characterized clinical phenotype conducted consecutive negative tests Contact tracing coronavirus coronavirus disease Coronavirus disease 2019 Critically ill critically ill patients detection disease disease control disease severity Duration emergency department first positive four group four groups Hospitalized in viral individual individuals Infectious disease Infectivity intensive care intensive care unit intensive care units interquartile range investigated Italian Italy measure median Mild disease multivariate analyses Multivariate analysis nasopharyngeal Nasopharyngeal swab nasopharynx negativity no difference Patient PCR tests positive individual positive individuals positive test result real-time RT-PCR real-time RT-PCR test respiratory RT-PCR test RT-PCR tests SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specimen standard error symptomatic patient Symptomatic patients symptomatic status test result tested university university hospital upper respiratory upper respiratory tract Viral viral shedding Virology with mild disease [DOI] 10.1016/j.cmi.2020.08.041 PMC 바로가기 [Article Type] Article
Anti–SARS-CoV-2 Antibody Responses in Convalescent Plasma Donors Are Increased in Hospitalized Patients; Subanalyses of a Phase 2 Clinical StudyArticle Published on 2020-11-282022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] age Analysis antibodies antibody antibody isotype Antibody titers Asymptomatic asymptomatic patients clinical collected Complete convalescent plasma correlated COVID-19 domain Donor donors ELISA evaluated first symptom Hospitalization hospitalized patient in-house ELISA Increased median time Multiplex assay neutralize Novel coronavirus nucleocapsid patients Phase 2 positive PCR Protein pseudotype RBD Recombinant spike protein response SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 virus selected significantly symptom onset the antibody response virus-neutralizing antibody [DOI] 10.3390/microorganisms8121885 PMC 바로가기 [Article Type] Article
Sensitivity evaluation of 2019 novel coronavirus (SARS-CoV-2) RT-PCR detection kits and strategy to reduce false negative2019 신종 코로나바이러스(SARS-CoV-2) RT-PCR 검출 키트의 민감도 평가 및 위음성 감소 전략Research Article Published on 2020-11-182022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, SARS, [키워드] 2019 novel coronavirus addition asymptomatic patient asymptomatic patients community transmission Concentration COVID-19 disease criteria Detection sensitivity Diagnosis differential diagnosis discharge discharged patient discharged patients Early detection Epidemic evaluated Evidence false-negative false-negative results increase indicated initial less low viral load patients lowest Molecular diagnosis Mutation nucleic acid Nucleic acid detection nucleic acid RT-PCR test ORF1ab gene patients Prevention and control recommendation reduce respiratory respiratory infection respiratory infections RT-PCR detection RT-PCR test SARS-CoV-2 seeking specificity target validation kit Viral Viral load [DOI] 10.1371/journal.pone.0241469 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 seroprevalence in a Belgian cohort of patients with cystic fibrosis낭포성 섬유증 환자의 벨기에 코호트에서 SARS-CoV-2 혈청 유병률Article Published on 2020-11-012022-09-11 Journal: Journal of cystic fibrosis : official journal of t [Category] MERS, SARS, 진단, 치료기술, [키워드] anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 IgG antibodies anti-SARS-CoV-2 IgG antibody anti-SARS-CoV-2 IgM asymptomatic patient asymptomatic patients Belgium Clinical data Clinique cohort of patient collected concerning COVID-19 COVID-19 symptom COVID-19 symptoms Cystic cystic fibrosis detect Diagnosis difficulty fibrosis Government Hospitalized IgG IgG antibodies IgG antibody lockdown molecular one patient Patient positive respiratory respiratory symptom respiratory symptoms risk of COVID-19 SARS-CoV-2 SARS-CoV-2 seroprevalence Seroprevalence symptomatic patient virus with COVID-19 [DOI] 10.1016/j.jcf.2020.08.005 PMC 바로가기 [Article Type] Article
18F-FDG PET/CT in asymptomatic patients with COVID-19: the submerged iceberg surfacesCase Reports Published on 2020-11-012023-07-12 Journal: Japanese journal of radiology [Category] SARS, [키워드] 18F-FDG PET/CT asymptomatic patients Chest CT. COVID-19 [DOI] 10.1007/s11604-020-01006-3 PMC 바로가기 [Article Type] Case Reports
Evaluation of SARS-CoV-2 IgG antibody response in PCR positive patients: Comparison of nine tests in relation to clinical dataPCR 양성 환자에서 SARS-CoV-2 IgG 항체 반응 평가: 임상 데이터에 대한 9가지 검사 비교Research Article Published on 2020-10-272022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] Abbott addressed antibody Antibody test Antibody testing antibody tests asymptomatic patients biosensor Clinical data Clinical practice clinical symptom Clinical symptoms controls correlated correlation COVID-19 patient DiaSorin different time points early stage epidemiological studies epitope Euroimmun explain group highlight house LIPS nine patient groups PCR positive Previous studies previous study ranged Roche S-RBD SARS-CoV-2 antibody test SARS-CoV-2 antibody testing SARS-CoV-2 antibody tests SARS-CoV-2 IgG antibody sensitivity Sensitivity and specificity serum sample serum samples Seven SNIBE specificity symptom onset target protein Variation Viral Viral antigen was performed [DOI] 10.1371/journal.pone.0237548 PMC 바로가기 [Article Type] Research Article