Hepatitis B and C infection in patients undergoing biologic and targeted therapies for rheumatic diseasesReview Published on 2018-12-012023-06-16 Journal: Best practice & research. Clinical rheumatology [Category] B형 간염, [키워드] Biological DMARD Hepatitis Pre-emptive Reactivation Targeted. [DOI] 10.1016/j.berh.2019.03.008 [Article Type] Review
Design, Synthesis and Biological Evaluation of Novel Primaquine-Cinnamic Acid Conjugates of the Amide and Acylsemicarbazide TypeArticle Published on 2016-11-282022-10-30 Journal: Molecules [Category] Coronavirus, [키워드] 229E acid Activation activities Alter amide amide bond anticancer Antioxidative antioxidative activity Antiviral antiviral activity binding Biological CAD Cell cell line chloride cinnamic acid derivative Compound compounds Concentration concentrations conjugate Conjugates coronavirus cytostatic activity derivative DPPH evaluated Evidence functional group Hela highest inhibitor inhibitory activity LOX MCF-7 morphology motif novel performed primaquine reducing reported selective spacer synthesis Type [DOI] 10.3390/molecules21121629 PMC 바로가기 [Article Type] Article
Deciphering the biology of porcine epidemic diarrhea virus in the era of reverse geneticsArticle Published on 2016-05-202022-11-01 Journal: Virus research [Category] Coronavirus, MERS, [키워드] addressed approach association BAC Biological Cell culture cell line cell lines clone complementary disease disease phenotype emergence epidemic diarrhea function Genetic genetics help highlight identify implication in vitro lack less mitigate modulating nucleocapsid nucleocapsid protein ORF3 Pathogenesis pathogenic mechanisms pathogenicity PEDV Porcine epidemic diarrhea virus question reverse genetics RNA recombination Spike protein the spike protein Vaccine Vaccine development viral life cycle viral tropism virulence virus [DOI] 10.1016/j.virusres.2016.05.003 PMC 바로가기 [Article Type] Article
Pathosphere.org: pathogen detection and characterization through a web-based, open source informatics platformSoftware Published on 2015-12-292022-10-27 Journal: BMC Bioinformatics [Category] Coronavirus, [키워드] addition Analysis analyzed annotation bioinformatics Biological center Chemical Community complex coronavirus creating detect Government homology Host identify Illumina Infectious disease Ion iterative NCBI Next-generation sequencing NGS pathogen pathogen detection platform provide Result sequence sequenced Sequencing supplementary material Support tested the United State utility variety zoonotic [DOI] 10.1186/s12859-015-0840-5 PMC 바로가기 [Article Type] Software
Digital Genotyping of Macrosatellites and Multicopy Genes Reveals Novel Biological Functions Associated with Copy Number Variation of Large Tandem RepeatsMacrosatellites 및 Multicopy 유전자의 디지털 유전형 분석은 대규모 직렬 반복의 복사 수 변화와 관련된 새로운 생물학적 기능을 나타냅니다.Research Article Published on 2014-06-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accompanied accumulation accumulations Analysis approach approaches association Biological Biological functions changes in copy copy number correlation Digital DNA methylation DNA methylation levels Effect Effects eukaryotic Evolution example expansion extreme FIVE focus fraction function functional Gene Expression Genes Genome genome assembly Genome-wide association study genomes genomic Genotype GWAS hallmark hallmarks human population human populations humans identify include information lead Local loci majority mechanism modulating non-human primates novel nucleotide number Organisms phenotypic diversity Population Previous studies Repeat repeated selective selective pressure sequence significantly single nucleotide single nucleotide variation SNP SNPs suppression tandem tandem repeat tandem repeats transgenic utility Variability variant variants Variation variations [DOI] 10.1371/journal.pgen.1004418 PMC 바로가기 [Article Type] Research Article
Frequency and tendency of malaria in Colombia, 1990 to 2011: a descriptive study콜롬비아의 말라리아 발생 빈도와 경향, 1990년부터 2011년까지: 기술적 연구Research Published on 2014-05-292024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Biological Colombia Epidemiology malaria models Statistics [DOI] 10.1186/1475-2875-13-202 PMC 바로가기 [Article Type] Research
A guide to preparation of patients with inflammatory bowel diseases for anti-TNF-α therapyReview Article Published on 2014-03-262024-09-04 Journal: Medical science monitor : international medical jo [Category] 대상포진, [키워드] agents Biological Inflammatory bowel disease ulcerative colitis [DOI] 10.12659/MSM.890331 PMC 바로가기 [Article Type] Review Article
Biological and genetic characterization of a hemagglutinating coronavirus isolated from a diarrhoeic childArticle Published on 2005-12-072022-11-01 Journal: Journal of medical virology [Category] Coronavirus, [키워드] activity acute diarrhea Amino acid amplification Analysis antigenic and nucleotide sequence comparisions BCV Biological caused cDNA Cell cell cultures cells coronavirus Cytopathic effect cytopathogenicity detected diarrhea DNA sequence electron microscopy Enteritis found Gene Genetic genomic homology human and bovine HA coronaviruses Inc Infected M gene monoclonal antibody nucleotide occurred Particle polymerase chain rectal related reverse transcription Strains viral RNA genome virulent virus [DOI] 10.1002/jmv.1890440207 PMC 바로가기 [Article Type] Article