Launching a comparative effectiveness adaptive platform trial of monoclonal antibodies for COVID-19 in 21 days21일 만에 코로나19 단일클론항체 비교효과 적응형 플랫폼 시험 개시Clinical Trial Published on 2022-02-012022-09-12 Journal: Contemporary clinical trials [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] Adaptive platform trial antibody bamlanivimab black Casirivimab clinical trial clinical trials clinician COVID-19 Culture decrease demonstrated Effectiveness Efficacy Efficacy and safety etesevimab Hospitalization Imdevimab learning while doing likelihood limit mAb mAbs monoclonal antibodies monoclonal antibody outcome Outpatient Patient progression public health Randomized receiving SARS-CoV-2 severe coronavirus disease Treatment trial infrastructure White patient [DOI] 10.1016/j.cct.2021.106652 PMC 바로가기 [Article Type] Clinical Trial
Impact of Insurance Benefits and Education on Point-of-Care Ultrasound Use in a Single Emergency Department: An Interrupted Time Series AnalysisArticle Published on 2022-02-012022-10-30 Journal: Medicina [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] Analysis benefit changed chose clinician coronavirus disease Coverage defined education eligible patient Emergency emergency department evaluate help Impact increase in insurance Intensive Interrupted Intervention material objective pandemic Patient physician Point-of-Care ultrasound Result Retrospective study Sery significantly South Korea time treat Ultrasonography Ultrasound [DOI] 10.3390/medicina58020217 PMC 바로가기 [Article Type] Article
COVID-19 diagnosis from routine blood tests using artificial intelligence techniquesResearch article Published on 2022-02-012022-10-05 Journal: Biomedical Signal Processing and Control [Category] 변종, [키워드] Accuracy AUC average blood test blood tests can be used clinician Clinicians correlation coefficient COVID-19 COVID-19 diagnosis dataset datasets deep learning diagnose diagnosing Diagnosis disease feature highest imperative Interpretation Laboratory machine learning MCC Mutation Pearson positive Precision recall routine blood test sensitivity Seven Spearman specificity statistical t-test transmission rates unique virus was used were used worldwide pandemic [DOI] 10.1016/j.bspc.2021.103263 [Article Type] Research article
Severe versus common COVID-19: an early warning nomogram model중증 대 일반적인 covid-19 : 조기 경고 노모 그램 모델Research Paper Published on 2022-01-312022-09-01 Journal: Aging (Albany NY) [Category] 진단, [키워드] 95% CI 95% confidence interval age Analysis analyzed C-index C-reactive protein calibration curve China Clinical data Clinical outcome clinical outcomes clinician Cohort collected coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient CRP Dyspnea early warning nomogram model Factor Health help IL-6 independent interleukin interleukin-6 Logistic Logistic regression analysis lymphocyte Lymphocyte count multivariate National Health Commission Occurrence Probability risk factor Risk factors severe disease Severe patient severe patients severe versus common Spread Treatment validation validation cohort validation cohorts [DOI] 10.18632/aging.203832 PMC 바로가기 [Article Type] Research Paper
Cytomegalovirus pneumonitis amid COVID-19 chaos: the hidden enemy—a case reportCase Report Published on 2022-01-312022-10-30 Journal: Journal of Medical Case Reports [Category] COVID-19, SARS, [키워드] Active surveillance acute respiratory syndrome Case report cause clinician CMV cohorts connective tissue connective tissue disease coronavirus coronavirus disease Course COVID-19 Cytokine storm cytomegalovirus disease-associated favor female help Herpesviridae hidden higher risk immune dysregulation immune system Immunosuppressed immunosuppressive therapy increasingly infections inhibitor initial innate immune pathway innate immune pathways intensive care Interstitial lung disease interstitial pneumonia knowledge mimicking morbidity and mortality Occurrence overlap Patient Pneumonia reported SARS-CoV-2 severe coronavirus disease thought treated [DOI] 10.1186/s13256-022-03259-0 PMC 바로가기 [Article Type] Case Report
The stepwise process of integrating a genetic counsellor into primary care Research Published on 2022-01-312022-10-05 Journal: European Journal of Human Genetics [Category] 유전자 메커니즘, [키워드] analyzed Care clinician collaboration conducted described effective facilitate facilitator gcs Genetic genetics integration Interaction interview lack Model participant physician primary care Process provided reaction resistance Stage transcribed variety were recorded while [DOI] 10.1038/s41431-022-01040-x [Article Type] Research
Rationale, design and methods of VA-BRAVE: a randomized comparative effectiveness trial of two formulations of buprenorphine for treatment of opioid use disorder in veteransRandomized Controlled Trial Published on 2022-01-312022-10-04 Journal: Addiction Science & Clinical Practice [Category] SARS, 임상, [키워드] Buprenorphine clinical effectiveness clinician Comparative effectiveness trial conducted Cooperative COVID-19 pandemic criminal decrease disorder effective Effectiveness Epidemic evaluate facilitate Formulation Guidance hepatitis B HIV IMPROVE include Injectable measure medication moderate Open-label opioid Opioid use disorder outcome outcomes parallel group prevalence rate Prevent Primary outcome Program Psychiatric Psychological Randomized Randomized controlled trial rationale RCT reduce secondary Standard of care Symptoms treating Treatment Trial unique veteran veterans widespread [DOI] 10.1186/s13722-022-00286-6 PMC 바로가기 [Article Type] Randomized Controlled Trial
Epidemiology of emergency ambulance service calls related to COVID-19 in Scotland: a national record linkage studyOriginal Research Published on 2022-01-282022-10-29 Journal: Scandinavian Journal of Trauma, Resuscitation and [Category] COVID-19, SARS, [키워드] Ambulance ambulance service benefit change clinical care Clinical guidelines clinician cohort study collected COVID-19 COVID-19 in patient COVID-19 negative COVID-19 positive patient death diagnosed dispatch exceeded Health Service identify introduced Mortality mortality rate National NHS outcome pathway Patient positive Positive predictive value PPE presenting priority Result retrospective SAS Scottish service supplementary material Support Symptom System with COVID-19 [DOI] 10.1186/s13049-022-00995-6 PMC 바로가기 [Article Type] Original Research
Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial확인 된 또는 의심되는 박테리아 감염 (Batch)으로 입원 한 어린이의 바이오 마커 유도 항생제 치료 기간 : 무작위 대조 시험을위한 프로토콜Paediatrics Published on 2022-01-252022-09-10 Journal: BMJ Open [Category] Fulltext, SARS, 바이오마커, 임상, [키워드] Adverse drug reactions adverse effect Algorithm Analysis Antibiotic treatment antibiotic use Antibiotics approved Bacterial infection best Biomarker C reactive protein children clinician commenced conducted conjunction control arm Controlled COVID-19 pandemic death Diagnostic microbiology discharge dissemination East Ethics Follow-up Health hospital Hospital stay HRA include infections Infectious diseases International Intervention intravenous antibiotics National Health Service NHS North outcome paediatric intensive & critical care PCT peer-reviewed procalcitonin protocol public health randomised controlled trial RCT REC recruit reduce registration number Relapse Research respond Safety measure secondary Secondary outcomes treated Treatment trial protocol Two-arm utility West [DOI] 10.1136/bmjopen-2020-047490 PMC 바로가기 [Article Type] Paediatrics
Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration data in the OpenSAFELY platform영국에서 COVID-19 입원 후 전반적이고 원인 별 입원 및 사망 : Obensafely 플랫폼에서 연결된 1 차 진료, 2 차 치료 및 사망 등록 데이터를 사용한 코호트 연구Research Article Published on 2022-01-252022-09-10 Journal: PLoS Medicine [Category] 변종, [키워드] adjusted adjusted hazard ratio Admission adverse outcome age all-cause mortality approval causes clinician cohort study Comorbidities Comorbidity conducted Control controls Coronavirus disease 2019 COVID-19 COVID-19 group COVID-19 hospitalisation COVID-19 patient COVID-19 patients Cox regression death Dementia demographic characteristics Deprivation discharge discharged Ethnicity events Evidence Factor General population greater Health health problems healthcare higher risk highest highlighting hospital Hospital admission hospital discharge hospitalisation hospitalisations hospitalised illnesses in some individual infected with SARS-CoV-2 Infection Influenza initial limitation Lower respiratory tract lower respiratory tract infection lower risk male matched controls median age medium mental health Mortality MOST obesity OpenSAFELY outcome outcomes pandemic Patient patients platform Policy potential risk primary care problem problems public health raised rates of infection readmission researcher resources respiratory risk risk of death secondary care severe COVID-19 Sex significantly smoking status subsequent suggested survivor variants with COVID-19 [DOI] 10.1371/journal.pmed.1003871 PMC 바로가기 [Article Type] Research Article