Reliability of multi-site UK Biobank MRI brain phenotypes for the assessment of neuropsychiatric complications of SARS-CoV-2 infection: The COVID-CNS travelling heads studyArticle Published on 2022-09-292022-11-16 Journal: PLoS ONE [Category] SARS, 유전자 메커니즘, [키워드] acquisition Analysis ASL assessment automatically Brain brain phenotype Cambridge collected college comparable Complication complications of COVID-19 component correlation COVID dataset defined diagnostic diffusion Effect feasibility File functional General Electric healthy imaging indicated King limitation linear London Measures MRI Neuropsychiatric olfactory over Oxford participant Participants pathogenic mechanisms Patient protocol Quantitative reduced reliability repeated Research SARS-CoV-2 SARS-COV-2 infection sequence Siemen susceptibility UK biobank UKB Variability [DOI] 10.1371/journal.pone.0273704 PMC 바로가기
Functional Antibody Responses to Severe Acute Respiratory Syndrome Coronavirus 2 Variants in Children With Coronavirus Disease 2019, Multisystem Inflammatory Syndrome in Children, and After Two Doses of BNT162b2 VaccinationArticle Published on 2022-09-282022-11-15 Journal: The Journal of Infectious Diseases [Category] SARS, 변종, 진단, [키워드] acute respiratory syndrome ADCC age antibody B.1.1.529 BNT162b2 breadth children coronavirus coronavirus 2 coronavirus disease COVID COVID-19 COVID-19 vaccination cytotoxicity dose elicited enrolled functional greater Inflammatory MIS-C Neutralizing neutralizing antibody of BNT162b2 omicron pediatric protocol pseudovirus reduced respiratory response SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants serologic significantly syndrome vaccination variants [DOI] 10.1093/infdis/jiac215 PMC 바로가기
SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recoveryArticle Published on 2022-09-282022-11-15 Journal: Science Translational Medicine [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome affected animal model change coronavirus correlated COVID COVID-19 demonstrated detectable exceeded hamster highlight host response Human IAV individual Infection Infectious virus influenza A virus Injury interferon response kidney lack lung mechanism molecular mechanism olfactory Olfactory epithelium PASC pathology Perturbation Proinflammatory cytokine response Result SARS-CoV-2 SARS-COV-2 infection sustained T cell activation tissue transcriptional change unique viral clearance [DOI] 10.1126/scitranslmed.abq3059 PMC 바로가기
Hygienic behaviors during the COVID-19 pandemic may decrease immunoglobulin G levels: Implications for Kawasaki diseaseArticle Published on 2022-09-282022-11-15 Journal: PLoS ONE [Category] 진단, [키워드] accelerated Adults Affect all age group all age groups children control subject coronavirus disease COVID COVID-19 COVID-19 outbreak COVID-19 pandemic Decline declined decrease examined explain Health hygiene Hypothesis IgE IgG IgG level Immunoglobulin immunological parameter individual Infection Kawasaki disease Neonate nonspecific pandemic Patient predict quantified recorded significantly lower steadily decreased [DOI] 10.1371/journal.pone.0275295 PMC 바로가기
Dysregulated autoantibodies targeting vaso- and immunoregulatory receptors in Post COVID Syndrome correlate with symptom severityArticle Published on 2022-09-272022-11-15 Journal: Frontiers in Immunology [Category] 진단, [키워드] accompanied ADRA2A ADRB2 alteration analyzed Asymptomatic autoantibodies autoantibody autonomic Autonomic nervous system autonomous chronic chronic fatigue syndrome classification Classifier Control control group control groups correlated correlation COVID COVID-19 Diagnostic Criteria disease dysregulation Evidence exploratory study fatigue G-protein G-protein coupled receptor groups immunoregulation indicated involved ME/CFS, Mild-to-moderate MOST nervous system organ dysfunction outcomes Pathogenesis Patient patients plethora Post COVID syndrome random receptor receptors Regulatory renin-angiotensin system seronegative serum severity STAB1 subset Symptom symptom severity syndrome [DOI] 10.3389/fimmu.2022.981532 PMC 바로가기
Feasibility of an online antigen self-testing strategy for SARS-CoV-2 addressed to health care and education professionals in Catalonia (Spain). The TESTA’T- COVID ProjectArticle Published on 2022-09-272022-11-15 Journal: PLoS ONE [Category] SARS, 변종, 치료기술, [키워드] addressed Antigen Care caused COVID COVID-19 demonstrated feasibility feasible Health healthcare omicron participant positive professional SARS-CoV-2 School Spain variant [DOI] 10.1371/journal.pone.0275006 PMC 바로가기
Role of Demyelination in the Persistence of Neurological and Mental Impairments after COVID-19Article Published on 2022-09-252022-11-16 Journal: International Journal of Molecular Sciences [Category] 유전자 메커니즘, 치료기술, [키워드] acute phase Affect Brain changes in clinical evidence clinical study cognitive Cognitive impairment Combination Complication complications of COVID-19 COVID COVID-19 COVID-19 patients Demyelination detect disorders Factor fatigue Future help impairment include Inflammation Injury Insomnia knowledge lesions Long COVID manifestation mechanism Mental mental sequelae MRI Neuroimaging neurological neurological consequences Numerous Patient physiological post-COVID syndrome psychiatric disorder Psychological Quality of life quantification Quantitative Research role SARS-CoV-2 syndrome virus [DOI] 10.3390/ijms231911291 PMC 바로가기
A Study on the Nature of SARS-CoV-2 Using the Shell Disorder Models: Reproducibility, Evolution, Spread, and AttenuationArticle Published on 2022-09-232022-11-16 Journal: Biomolecules [Category] SARS, 변종, [키워드] applied attenuation bat-CoV contagiousness coronavirus Coronaviruses correlated CoV COVID COVID-19 demonstrated disorder enzyme greater Hard immune system implication intrinsic Long COVID lung membrane protein Nature nucleocapsid protein nucleoprotein observation omicron pangolin Particle PID predicted PROTECT Replication Saliva SARS-CoV-2 shell supported tissues transmissions variant Viral load virion virulence virus [DOI] 10.3390/biom12101353 PMC 바로가기
Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic systemArticle Published on 2022-09-212022-11-15 Journal: Cardiovascular Diabetology [Category] 바이오마커, 유전자 메커니즘, 진단, [키워드] absence addition analysed antibodies Anxiety Biomarker C-reactive protein cardiovascular disease Chronic fatigue circulation Clinicians Cognitive impairment Cohort Comorbidities Confusion contribute controls COVID COVID patient COVID-19 Depression detect disease Dyspnoea Evidence explain Failed fibrinolysis fatigue fibrinogen fibrinolytic system granular Health healthy controls Host immune response IL-6 implication increased risk individual Inflammatory inflammatory markers insoluble Kallikrein Long Long COVID mechanism Microclots PASC pathology Patient PF4 plasma Platelet platelet factor 4 platelet hyperactivation presence of antibody prevalent Prevent pro-inflammatory molecule Protein provided questionnaire reduced reported serum CRP sick Symptom thrombosis type 2 diabetes von Willebrand factor vWF [DOI] 10.1186/s12933-022-01623-4 PMC 바로가기
Use of LoopDeelab during the COVID-19 Pandemic: An Innovative Device for Field DiagnosisArticle Published on 2022-09-172022-11-15 Journal: Viruses [Category] SARS, 치료기술, [키워드] analysed Analysis attack rate collected Concordance conducted COVID COVID-19 COVID-19 outbreak Device diagnosis of SARS-CoV-2 diagnostic double-blind Epidemics evaluate facilitate field France Health Infection intrinsic knowledge LAMP PCR Loopdeelab Loopdeetect management Measures molecular nasopharyngeal swab specimen PCR Rapid RAPID COVID Research protocol RT-LAMP RT-PCR SARS-CoV-2 Seegene, Korea Sensitivity and specificity [DOI] 10.3390/v14092062 PMC 바로가기