A Novel Coronavirus Disease (COVID-19): a Review of Host Cell Signaling PathwaysReview Article Published on 2020-11-012022-10-28 Journal: Tanaffos [Category] COVID-19, [키워드] acute respiratory syndrome caused changes in coronavirus coronavirus disease CoV COVID-19 CoVs develop evaluate genetic variants Health Healthcare system Host host cell host cell factor host-pathogen interaction host-pathogen interactions Inflammation innate immune system Interaction lung Lung inflammation molecular novel pandemic persistence physician positive-sense progression proliferation promote recognize reduce review risk RNA viruses SARS-CoV-2 signaling pathway signaling pathways targeted therapy PMC 바로가기 [Article Type] Review Article
Determine the Potential Epitope Based Peptide Vaccine Against Novel SARS-CoV-2 Targeting Structural Proteins Using Immunoinformatics ApproachesMolecular Biosciences Published on 2020-10-152022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] Against Analysis analyzed antigenic epitope antigenic site approach B-cell epitope binding binding affinity caused China corona virus disease 2019 coronavirus CoV COVID-19 CoVs CTL cytotoxic diagnosed disease docking complex effective envelope epitope high mortality rate HLA Human immunoinformatics introduced mammal MHC-I new strain novel pathogenic virus peptide Peptide vaccines positive Potential predict predicted Replication RNA genome RNA virus SARS-CoV SARS-CoV-2 SARS-CoV-2 coronavirus spike structural protein targeting unique Vaccine variety Wuhan [DOI] 10.3389/fmolb.2020.00227 PMC 바로가기 [Article Type] Molecular Biosciences
Zoonotic and reverse zoonotic events of SARS-CoV-2 and their impact on global healthReview Published on 2020-10-142022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, Fulltext, MERS, SARS, 조류인플루엔자, [키워드] approach bat coronavirus CoV COVID-19 CoVs Critical care event globe Health healthcare service highlight human CoV humans infect limit One-Health One-World outbreak Pandemics positive recent reservoir respiratory responsible reverse zoonosis SARS-CoV-2 SARS-COV-2 infection secondary zoonosis Seven Single-stranded RNA viruses Spread virus zoonosis zoonotic zoonotic infections zoonotic origins [DOI] 10.1080/22221751.2020.1827984 PMC 바로가기 [Article Type] Review
The Inflammasome in Times of COVID-19Immunology Published on 2020-10-082022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Activation Activation of caspase-1 acute respiratory distress acute respiratory syndrome affected ARDS Brain caspase-1 contribute coronavirus CoV infection COVID-19 COVID-19 patients CoVs digestive disease downstream Effect genus Betacoronavirus Hyperactivation IL-1beta IL-1β IL-6 Infection Inflammasome inflammasome activation Inflammation Inflammatory cytokine Inflammatory response intestine involved kidneys Lungs mechanism MERS Middle East multiprotein complex nervous system potential mechanism renal respiratory infection responsible shown syndrome time tissue variety Ventilator-induced lung injury [DOI] 10.3389/fimmu.2020.583373 PMC 바로가기 [Article Type] Immunology
Host Receptors of Influenza Viruses and Coronaviruses—Molecular Mechanisms of RecognitionReview Published on 2020-10-062022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] caused coronavirus Coronaviruses CoV COVID-19 pandemic CoVs death detectable Epidemic Fatality rate H1N1 HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 host range host receptor human CoVs humans IAV IBV immunologically Infection infections Influenza influenza A virus influenza B Influenza virus influenza viruses knowledge Lineage mild respiratory naïve outbreak pandemic protein receptors Receptor binding receptors Recognition recorded sialyl glycans specificity spike glycoproteins spikes structures Subtypes variants virus virus variants viruses zoonotic [DOI] 10.3390/vaccines8040587 PMC 바로가기 [Article Type] Review
SARS-CoV-2 S1 and N-based serological assays reveal rapid seroconversion and induction of specific antibody response in COVID-19 patientsArticle Published on 2020-10-062022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 유전자 메커니즘, 치료기술, [키워드] Antibody Response caused collected Contact COVID-19 COVID-19 patient COVID-19 patients CoVs cross-reactivity cut off different time point disease onset ELISA Epidemiological study healthy controls human coronavirus IgG antibody Inclusion individuals Infection nucleocapsid populations positive RT-PCR SARS-CoV-2 SARS-CoV-2 S1 sensitivity Sensitivity and specificity sera Seroconversion Serological assay Serological testing seropositive specific IgM specificity spike glycoprotein Spread subunit tested the antibody response viral infection virus virus spread [DOI] 10.1038/s41598-020-73491-5 PMC 바로가기 [Article Type] Article
The Role of the Dental Surgeon in Controlling the Dissemination of COVID-19: A Literature ReviewReview Article Published on 2020-10-012022-10-29 Journal: The Scientific World Journal [Category] COVID-19, MERS, [키워드] biosafety China concerning Contamination Control controlling coronavirus coughing COVID-19 COVID-19 pandemic CoVs dental dentist diarrhea Dyspnea emerging disease etiology Fever Guidance high risk imperative implication Infection prevention literature literature review malaise Measures Nidovirale occurred Orthocoronavirinae Patient patients with pneumonia professional raising review role salivary SARS-CoV-2 sore throat sputum Symptom the Coronaviridae transmitted treat virus [DOI] 10.1155/2020/7945309 PMC 바로가기 [Article Type] Review Article
Coronavirus in human diseases: Mechanisms and advances in clinical treatmentReview Published on 2020-10-012022-10-30 Journal: MedComm [Category] COVID-19, [키워드] 3CLpro accessory protein acute respiratory syndrome Antiviral agents antiviral drug association Cell Clinical treatment clinical treatments coronavirus COVID‐19 COVID‐19 CoVs current disease effective Helicase highlight Human human coronaviruses human diseases infections mechanism MERS Middle East Mild pathogen PLPro Protein provide RdRP RNA virus S protein SARS SARS‐CoV‐2 signaling pathway strain syndrome target therapeutic option Therapeutic strategies Treatment treatment strategy upper respiratory viral life cycle virus [DOI] 10.1002/mco2.26 PMC 바로가기 [Article Type] Review
Papain-Like Proteases as Coronaviral Drug Targets: Current Inhibitors, Opportunities, and LimitationsReview Published on 2020-09-282022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] acute respiratory syndrome boost caused Compound coronavirus Coronavirus disease 2019 Coronavirus-2 CoV COVID-19 CoVs current drug effective feature Host immune response immune system inhibitor limitation MERS-CoV Middle East Mutation outbreak papain-like proteases Perspective PLPro Prevent protease SARS-CoV SARS-CoV-2 structures Support suppress syndrome targets the patient viral genome viral replication [DOI] 10.3390/ph13100277 PMC 바로가기 [Article Type] Review
SAMHD1 as the Potential Link Between SARS-CoV-2 Infection and Neurological ComplicationsNeurology Published on 2020-09-252022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome ADAR angiotensin-converting enzyme 2 bioinformatics BST2 caused cells chemokines clinical symptom Complication complications of COVID-19 coronavirus correlation CoV COVID-19 COVID19 CoVs Cytokines death Dipeptidyl peptidase 4 dissemination DPP4 event expression globe IFITM3 Infection influenza A virus IRF3 ISG15 mechanism MERS-CoV Middle East morbidity MX1 MX2 neurodegeneration neuroinvasion neurologic neurological Neurological complication Neurological symptoms NF-κB pathway other molecule pandemic Pathogenesis peripheral nerve system Pneumonia Potential produced Prognosis receptor respiratory syncytial virus RNASEL robust RSAD2 SAMHD1 SAR-CoV2 SARS-CoV-1 SARS-CoV-2 Spread STRING syndrome text mining triggered Type type III interferon with COVID-19 [DOI] 10.3389/fneur.2020.562913 PMC 바로가기 [Article Type] Neurology