cross-reactivity – Page 17 – Communicable Diseases Research

From Anti-SARS-CoV-2 Immune Response to the Cytokine Storm via Molecular Mimicry

Article

Published on 2021-09-242022-10-27
Journal: Antibodies [Category] COVID-19,

Cross-neutralization of SARS-CoV-2 by HIV-1 specific broadly neutralizing antibodies and polyclonal plasma

Research Article

Published on 2021-09-242022-10-29
Journal: PLoS Pathogens [Category] COVID-19, SARS,

[키워드] antibodies antibody antigenic Atypical binding site CD4 CDR complementary COVID-19 pandemic Critical cross cross-react cross-reactive cross-reactive antibody cross-reactivity defined epitope Evidence feature Features fusion protein glycan glycans glycosylated HIV-1 HIV-1 infection Host Human monoclonal antibody infected children influenza hemagglutinin monoclonal antibody neutralization neutralize neutralized Neutralizing Neutralizing activity neutralizing antibody observation Pandemics pathogen plasma plasma antibody polyclonal processed recognize recovered patients responses S protein SARS-CoV-2 SARS-CoV-2 pseudoviruses SARS-CoV-2 spike protein shown somatic hypermutations type I tyrosine understanding unique Variability variant Variation viral infection virus
[DOI] 10.1371/journal.ppat.1009958 PMC 바로가기 [Article Type] Research Article

An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope

초강력 범-β-코로나바이러스 계통 B(β-CoV-B) 중화 항체는 보존된 에피토프를 표적으로 하여 닫힌 형태로 수용체 결합 도메인을 잠급니다

Research Article

Published on 2021-09-232022-09-10
Journal: Protein & Cell [Category] MERS, SARS, 변종, 진단,

[키워드] ACE2 binding ACE2 binding site administration Analysis antibody antibody-dependent cell-cell fusion antigenic binding binding antibody cell-cell fusion circulating variant circulating variants competing conserved cross-reactivity develop domain effective epitope Epitopes family member family members highlight in vivo induce Lineage neutralize neutralizes neutralizing antibody neutralizing epitope neutralizing epitopes New protective vaccine RBD Receptor-binding domain Recognition recognize reduced SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 variant SARSr-CoV WIV1 supplementary material the RBD the receptor-binding domain therapeutic therapeutic antibodies therapy threat unique Vaccine design XG005 XG014 β-coronavirus
[DOI] 10.1007/s13238-021-00871-6 PMC 바로가기 [Article Type] Research Article

Monoclonal Antibodies to S and N SARS-CoV-2 Proteins as Probes to Assess Structural and Antigenic Properties of Coronaviruses

Article

Published on 2021-09-222022-10-28
Journal: Viruses [Category] COVID-19, SARS,

[키워드] acute respiratory syndrome addition analyses antibodies antigenic can be used Complete conducted coronavirus Coverage COVID-19 cross-reactivity Diagnosis exhibiting facilitate functional Infection mAb mAbs Middle East monoclonal antibody Mutation N protein neutralization Neutralizing activity neutralizing epitope nucleocapsid nucleocapsid protein Partial property Protein Research responsible S-RBD SARS-CoV SARS-CoV N protein SARS-CoV-2 SARS-CoV-2 N protein specific antibody specificity Spike protein spike receptor-binding domain syndrome tested the N protein the RBD the S protein the SARS-CoV-2 to define Treatment unique variants of concern virus virus replication were assessed
[DOI] 10.3390/v13101899 PMC 바로가기 [Article Type] Article

SARS-CoV-2 Antibody Rapid Tests: Valuable Epidemiological Tools in Challenging Settings

Research Article

Published on 2021-09-222022-10-30
Journal: Microbiology Spectrum [Category] COVID-19, MERS, SARS,

[키워드] acute respiratory syndrome addition affecting Analysis analyzed antibody tests carried collected coronavirus country COVID-19 COVID-19 patient cross-reactivity demonstrated detect diagnostic test different time point Diseases dose electrochemiluminescence immunoassay elicited ELISA employment Endemic enzyme-linked immunosorbent Epidemiology evaluated first dose Health care worker identify IgG IgG response Immunological response individual lack large-scale analysis Lateral Lateral flow assays low-middle-income countries Patient performance Perspective Pfizer-BioNTech point-of-care tests Population screening postvaccination provide question Rapid RBD Receptor binding domain response to vaccination risk S protein SARS-CoV-2 SARS-CoV-2 immunology SARS-COV-2 infection sensitivity Sensitivity and specificity setting specificity subjects Support symptom onset the SARS-CoV-2 therapy Treatment Tuberculosis vaccination Vaccine was used
[DOI] 10.1128/Spectrum.00250-21 PMC 바로가기 [Article Type] Research Article

Differential pre-pandemic breast milk IgA reactivity against SARS-CoV-2 and circulating human coronaviruses in Ugandan and American mothers

Article

Published on 2021-09-202023-06-15
Journal: International Journal of Infectious Diseases [Category] MERS, SARS,

[키워드] Breast milk IgA COVID-19 cross-reactivity human coronaviruses SARS-CoV-2 Spike proteins
[DOI] 10.1016/j.ijid.2021.09.039 PMC 바로가기 [Article Type] Article

To Be or Not To Be Vaccinated: That Is a Question in Myasthenia Gravis

Immunology

Published on 2021-09-172022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, SARS,

In Vitro Rapid Antigen Test Performance with the SARS-CoV-2 Variants of Concern B.1.1.7 (Alpha), B.1.351 (Beta), P.1 (Gamma), and B.1.617.2 (Delta)

Communication

Published on 2021-09-162022-10-29
Journal: Microorganisms [Category] COVID-19,

[키워드] 229E Antigen B.1.1 B.1.1.7 B.1.1.7 (Alpha) B.1.351 B.1.351 (Beta) B.1.617.2 B.1.617.2 (Delta) Beta cell culture medium circulating comparable concern conducted containment strategies cross-reactivity Delta detect dilution sery evaluated Gamma HCoV HCoVs HKU1 human corona viruses (hCoVs) human coronavirus investigated Laboratory limit of detection mutations N-protein nasal swab NL63 OC43 P.1 P.1 (Gamma) pathogen performance Rapid rapid antigen test performance RAT RATs required Saliva SARS-CoV-2 SARS-CoV-2 rapid antigen tests strain Strains Test the SARS-CoV-2 variants variants of concern variants of concern (VOCs) VoC VOCs was determined
[DOI] 10.3390/microorganisms9091967 PMC 바로가기 [Article Type] Communication

Human Codon Usage: The Genetic Basis of Pathogen Latency

Original Article

Published on 2021-09-142024-09-02
Journal: Global Medical Genetics [Category] 대상포진,

[키워드] (re)activation codon optimization codon usage cross-reactivity pathogen latency protein synthesis tRNAs
[DOI] 10.1055/s-0041-1729753 PMC 바로가기 [Article Type] Original Article

Is preexisting immunity to seasonal coronaviruses limited to cross-reactivity with SARS-CoV-2? A seroprevalence cross-sectional study in north-eastern France

계절성 코로나바이러스에 대한 기존 면역은 SARS-CoV-2와의 교차 반응성으로 제한됩니까? 프랑스 북동부의 혈청유병 횡단면 연구

Commentary

Published on 2021-09-122022-09-12
Journal: EBioMedicine [Category] SARS, 진단,

[키워드] cross-reactivity cross-sectional France Preexisting immunity seasonal coronavirus
[DOI] 10.1016/j.ebiom.2021.103580 PMC 바로가기 [Article Type] Commentary