Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2약물-유도인지 지질증은 SARS-CoV-2에 대한 약물 용도를 혼란스럽게한다Article Published on 2021-10-032022-09-10 Journal: Science (New York, N.y.) [Category] MERS, SARS, 신약개발, 치료기술, 치료제, [키워드] active against acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Amiodarone Antiviral antiviral activity antiviral efficacy Azithromycin cationic caused clinical trials coronavirus correlated drug Drug discovery drug-induced Early detection focus Hydroxychloroquine induce Ligand mechanism molecules Phospholipidosis Physicochemical properties physicochemical property receptor Repurposed drugs repurposing respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus target tested the disease therapeutic potential treatments for COVID-19 [DOI] 10.1126/science.abi4708 PMC 바로가기 [Article Type] Article
Mental health status and quality of life in close contacts of COVID-19 patients in the post-COVID-19 era: a comparative study코로나19 이후 시대 코로나19 환자 밀접접촉자의 정신건강상태와 삶의 질: 비교연구Article Published on 2021-10-022022-09-10 Journal: Translational Psychiatry [Category] MERS, SARS, 치료기술, [키워드] age Analysis Analysis of covariance checklist close contact Contact covariance COVID-19 COVID-19 patient cross-sectional cross-sectional study demographic demographic data Depression depressive Depressive symptoms determine distress Early detection Effect Effects examined fatigue group groups Health Organization Health status independent Intervention life long-lasting media mental health multiple logistic regression no significant differences Perception performed PHQ-9 Post-traumatic stress disorder post-traumatic stress symptom Post-traumatic stress symptoms provided Psychiatric disorders Quality Quality of life reported Scientific community severe depression significant difference significantly significantly more traumatic stress symptoms was used were assessed with COVID-19 World Health Organization [DOI] 10.1038/s41398-021-01623-0 PMC 바로가기 [Article Type] Article
COVID-19 Incidence and Mortality Among Long-Term Care Facility Residents and Staff in South Carolina사우스 캐롤라이나의 장기 요양 시설 입소자와 직원의 COVID-19 발병률 및 사망률Article Published on 2021-10-012022-09-11 Journal: Journal of the American Medical Directors Associat [Category] SARS, 치료기술, [키워드] age calculated Care chronic health conditions Community Control COVID-19 COVID-19 cases COVID-19 diagnosis COVID-19 incidence COVID-19 mortality Cox proportional hazard Cox proportional hazards Data analysis death Department Descriptive statistics disease spread Early detection employment facility Gender greater help hospitalizations Hospitalized incidence incidence of cases Infection Long-term care long-term care facilities longitudinal LTC Mortality mortality rate mortality rates Older Older adults Prevent Regulation residence resident Result setting South Spread staff study period with COVID-19 [DOI] 10.1016/j.jamda.2021.08.006 PMC 바로가기 [Article Type] Article
Post-COVID-19 symptoms 6 months after acute infection among hospitalized and non-hospitalized patients입원환자와 비입원환자의 급성 감염 후 6개월 후 증상Article Published on 2021-10-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI acute infection acute respiratory syndrome age anti-SARS-CoV-2 IgG bidirectional chronic Chronic COVID coronavirus coronavirus 2 COVID COVID survivors COVID-10 COVID-19 disease disease onset Early detection evaluated Factor female female gender Follow-up Gender Hospitalized ICU admission identify IgG antibodies IgG antibody increase in independent risk factor independent risk factors individual Inpatient interview investigated IQR Italy Long Long COVID median number of symptom Occurrence offered onset of symptoms Outpatient outpatients Patient patients Patients with post-COVID-19 syndrome post-COVID syndrome predictor Prevalence Prospective Prospective Study respiratory SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 IgG SARS-CoV-2 serology serological serology severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly significantly higher subgroup Symptom syndrome the disease the interview titre typical symptom typical symptoms with COVID-19 without symptom [DOI] 10.1016/j.cmi.2021.05.033 PMC 바로가기 [Article Type] Article
Bad law or implementation flaws? Lessons from the implementation of the new law on epidemics during the response to the first wave of COVID-19 in Switzerland나쁜 법률 또는 구현 결함? 스위스 COVID-19의 첫 번째 물결에 대응하는 동안 전염병에 관한 새로운 법률 시행에서 얻은 교훈Article Published on 2021-10-012022-09-11 Journal: Health policy (Amsterdam, Netherlands) [Category] SARS, 신종인플루엔자, 치료기술, [키워드] applied COVID-19 COVID-19 pandemic delayed response disease outbreak Diseases Early detection Epicentre Epidemics Europe excluded First wave force H1N1 H1N1 pandemic implementation Infectious diseases International international cooperation introduced involved Italian lesson lombardy management mechanism outbreak pandemic pharmaceutical industry problem Public public health referendum reform Spread Surveillance survived Switzerland tension Vaccine [DOI] 10.1016/j.healthpol.2021.08.004 PMC 바로가기 [Article Type] Article
The impact of the Covid-19 pandemic on breast cancer early detection and screening코로나19 팬데믹이 유방암 조기 발견 및 검진에 미치는 영향Article Published on 2021-10-012022-09-11 Journal: Preventive medicine [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] Affect Analysis applied Breast Breast cancer calibrated Cancer screening COVID-19 COVID-19 pandemic diagnose Diagnosis Early detection early diagnosis effort example expected group Health services incidence increased mortality Intensive International life mitigate modelling morbidity Mortality Multiple outcome pandemic Quality of life reduced response resulting Screening strained Support survival treat Treatment working [DOI] 10.1016/j.ypmed.2021.106585 PMC 바로가기 [Article Type] Article
Multiparameter diagnostic sensor measurements in heart failure patients presenting with SARS-CoV-2 infectionSARS-CoV-2 감염이 있는 심부전 환자의 다중 매개변수 진단 센서 측정Article Published on 2021-10-012022-09-11 Journal: ESC heart failure [Category] SARS, 치료기술, [키워드] ambulatory Ambulatory monitoring amplitude change changed changes in COVID-19 CRT diagnostic diagnostics Early detection extreme greater heart heart failure heart rate Heart sound heart sounds Hospitalization hospitalizations ICD Implantable device increase in marker occur parameter Patient Pneumonia predict presenting respiratory rate Retrospective analysis SARS-CoV-2 SARS-COV-2 infection shallow breathing shown significant changes in sustained temperature Thoracic trials Ventilation worsening [DOI] 10.1002/ehf2.13500 PMC 바로가기 [Article Type] Article
Overcoming Current and Preventing Future Nosocomial Outbreaks during the COVID-19 Pandemic: Lessons Learned at Three Hospitals in JapanCOVID-19 전염병 동안 현재를 극복하고 미래의 병원 발병을 예방: 일본의 세 병원에서 배운 교훈Article Published on 2021-09-282022-09-10 Journal: International Journal of Environmental Research an [Category] SARS, 치료기술, [키워드] analyzed asymptomatic transmission Care conducted confirmation contribute coronavirus disease Coronavirus disease 2019 COVID-19 current damage domain Early detection expected Factor Future Health Health care health system hospital hospitals increasingly Infection infection control Infection prevention infection prevention control information Japan knowledge lesson measure Measures mitigate Nosocomial infection occurred outbreak Outbreaks pandemic PCR test Prevent Preventing Prevention and control required SARS-CoV-2 suggested Support Transmission [DOI] 10.3390/ijerph181910226 PMC 바로가기 [Article Type] Article
Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolatesSARS-COV-2 스파이크 당 단백질 돌연변이 체의 대규모 분석Research Article Published on 2021-09-272022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] Analysis analyzed Antibody binding approved Co-infection COVID-19 pandemic data set data sets dataset Early detection ENA European Nucleotide Archive Evolution exhibiting genome assembly GISAID glycoprotein human populations immune response immune responses increase in induce Infection less majority median mRNA vaccine mRNA vaccines mutant mutant spike protein mutants Mutation mutation rate NGS Non-synonymous mutation nucleotide reported SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genome assembly SARS-CoV-2 sequence SARS-CoV-2 sequences SARS-CoV-2 strain Spike protein strain T-cell the mean the SARS-CoV-2 genome the spike protein Therapeutic strategies variant variants Variation virus isolate widespread wild-type [DOI] 10.1371/journal.pone.0249254 PMC 바로가기 [Article Type] Research Article
Turning a Corner in ME/CFS ResearchME/CFS 연구의 한 획을 긋다Review Published on 2021-09-252022-09-10 Journal: Medicina [Category] SARS, 치료기술, [키워드] approach Care chronic fatigue syndrome clinical clinical care Coalition concerning COVID-19 diagnosed Diagnosis doctor Early detection Encephalomyelitis European Evidence fatigue syndrome Guidance guideline Impact implication include Infection Intervention issue knowledge knowledge and understanding lack life management ME/CFS myalgic encephalomyelitis Nice organizations overlap paper Patient problem proportion Quality of life question reminder Research secondary prevention Symptoms syndrome Turning USA [DOI] 10.3390/medicina57101012 PMC 바로가기 [Article Type] Review