Evolution of Neuroimaging Findings in Severe COVID-19 Patients with Initial Neurological Impairment: An Observational StudyObservational Study Published on 2022-05-012022-10-05 Journal: Viruses [Category] 임상, [키워드] acute phase age average Brain cerebral Complication COVID-19 COVID-19 outbreak COVID-19 patient demonstrated described eight Evolution finding First wave FIVE FLAIR Follow-up Hospitalized hospitals increase in Inflammatory initial intensive care units leptomeningeal lesion manifestation men MRI Neuroimaging neurologic outcome Patient patients regions severe COVID-19 patient university Vascular Vasculitis vessel wall Volume women [DOI] 10.3390/v14050949 PMC 바로가기 [Article Type] Observational Study
The effects of add-on therapy of Phyllanthus Emblica (Amla) on laboratory confirmed COVID-19 Cases: A randomized, double-blind, controlled trialRandomized Controlled Trial Published on 2022-05-012022-10-05 Journal: Complementary therapies in medicine [Category] COVID19(2023년), SARS, 임상, [키워드] Affect Arm assigned baseline Biomarker C-reactive protein test chain changes in Characteristics chill Clinical outcome Clinical sign Clinical symptoms clinical variable control arm Controlled trial cough COVID-19 COVID-19 patients CRP levels CT scans demographics diagnostic double-blind Effect eight evaluate the effect evaluated Fever hospital increase in Intervention intervention arm Laboratory LOS lung involvement marker myalgia not significant not significantly different organic oxygen saturation Patient Phyllanthus Phyllanthus Emblica Phyllanthus Emblica. Randomized Randomly RCT reaction reduction in respiratory rate RT-PCR severity Shortness of breath significantly significantly shorter sore throat SpO2 study group Symptom the mean therapy two group variable variables weakness were assessed [DOI] 10.1016/j.ctim.2022.102808 PMC 바로가기 [Article Type] Randomized Controlled Trial
Outcomes of single dose COVID-19 vaccines: Eight month follow-up of a large cohort in Saudi ArabiaResearch article Published on 2022-05-012022-10-05 Journal: Journal of infection and public health [Category] COVID19(2023년), SARS, 임상, [키워드] Administered adverse event AEs approved average AZD1222 BNT162b2 body mass index Breakthrough infection Clinical data clinical trials co-morbidity Cohort collected conducted COVID-19 COVID-19 infection COVID-19 vaccine demographics dose Effect Effectiveness eight fatigue Fever Follow-up had no headache higher risk Infection injection site pain interactions Kingdom large cohort majority male median age medical records myalgia National obese obesity Occurrence organ outcome pandemic parameters participant prospective cohort study real-world data reported Result risk factor Saudi Arabia side single dose Single-dose social interaction subject subjects the vaccine Travel vaccination Vaccine Vaccines [DOI] 10.1016/j.jiph.2022.04.001 [Article Type] Research article
SARS-CoV-2 circulation in Croatian wastewaters and the absence of SARS-CoV-2 in bivalve molluscan shellfish크로아티아 폐수에서 SARS-CoV-2 순환 및 이매패류 연체동물 조개에서 SARS-CoV-2 부재Article Published on 2022-05-012022-09-11 Journal: Environmental research [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] absence amplification Bioaccumulation Bivalve molluscan shellfish BMS circulation collected Community Concentration Contamination criterion Croatia eight Epidemic epidemic wave food safety knowledge mengovirus nine nsp14 plant processed Protein provided real-time RT-PCR Research risk rotavirus Rotavirus A RT-PCR assay SARS-CoV-2 SARS-CoV-2 detection Sequencing shellfish surface Surface water Surface waters Treatment virus warty was performed Wastewaters. water [DOI] 10.1016/j.envres.2021.112638 PMC 바로가기 [Article Type] Article
Healthy humans can be a source of antibodies countering COVID-19건강한 사람은 COVID-19에 대항하는 항체의 원천이 될 수 있습니다Article Published on 2022-05-012022-09-11 Journal: Bioengineered [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제, [키워드] ACE2 ACE2 competitor Analysis angiotensin angiotensin-converting enzyme 2 antibody antibody cocktail approach authentic SARS-CoV-2 virus best binding binding affinity Blood bypassing can be used characterized Combination COVID-19 COVID-19 diagnostics COVID-19 therapeutics detect detecting antibody diagnostic eight ELISA epitope Epitopes Evidence Evolution flow cytometry fluorescence microscopy healthy donor healthy donors Human humanized IgG immune in vitro infected patients Infection inhibit SARS-CoV-2 Isolation mice monoclonal antibodies naïve neutralization titers neutralize neutralizing antibody RBM receptor Receptor binding domain receptor-binding motif recognize SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 virus single B cell single-chain antibody specificity Spike protein SPR tested therapeutic unique virus infection yeast [DOI] 10.1080/21655979.2022.2076390 PMC 바로가기 [Article Type] Article
Reported cases of multisystem inflammatory syndrome in children aged 12-20 years in the USA who received a COVID-19 vaccine, December, 2020, through August, 2021: a surveillance investigation2020년 12월부터 2021년 8월까지 COVID-19 백신을 접종한 미국의 12-20세 어린이에서 보고된 다기관 염증 증후군 사례: 감시 조사Article Published on 2022-05-012022-09-11 Journal: The Lancet. Child & adolescent health [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료법, [키워드] Adverse age Anti-nucleocapsid antibodies anti-nucleocapsid antibody Anti-spike antibody assessment calculate CDC center children clinical clinical feature clinician Control count COVID-19 vaccination COVID-19 vaccine discharged home disease control dose drug Drug administration eight Emergency use Evidence evidence of female food Hyperinflammatory illness illness onset individual individuals Infection Inflammatory intensive care intensive care unit investigated Laboratory male median age MIS-C National past positive prevention Protein receiving reported Reporting required Safety SARS-CoV-2 SARS-COV-2 infection serology test stratified Surveillance surveillance data syndrome System US Food and Drug Administration USA vaccinated individuals vaccination Vaccine [DOI] 10.1016/S2352-4642(22)00028-1 PMC 바로가기 [Article Type] Article
SARS-CoV-2 infections in households in a peri-urban community of Lima, Peru: A prospective cohort study페루 리마의 교외 지역사회 가정에서 발생한 SARS-CoV-2 감염: 전향적 코호트 연구Article Published on 2022-05-012022-09-11 Journal: Influenza and Other Respiratory Viruses [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] 95% CI 95% confidence interval Adults age Baseline serology blood sample Blood samples calculated Child children Cohort collected Community COVID-19 defined demonstrated eight enrolled Enrollment Evidence evidence of Follow-up household Households incidence Infection laboratory-confirmed laboratory-confirmed SARS-CoV-2 infection Lambda Ministry of Health MOST nasal swabs Nasopharyngeal swab nasopharyngeal swabs new SARS-CoV-2 occurred Older participant period prevalence Peru positive Prevalence prospective cohort study Prospective Study Rapid serological tests risk RT-PCR test saliva specimen saliva specimens SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 infections Serological tests serology specimen subject Swab symptomatic Symptoms tested twice weekly variant [DOI] 10.1111/irv.12952 PMC 바로가기 [Article Type] Article
Pharmacophore based virtual screening for natural product database revealed possible inhibitors for SARS-COV-2 main protease천연물 데이터베이스에 대한 약전 기반 가상 스크리닝을 통해 SARS-COV-2 주요 프로테아제에 대한 가능한 억제제가 밝혀졌습니다.Article Published on 2022-05-012022-09-11 Journal: Virology [Category] COVID19(2023년), SARS, 치료제, [키워드] absence antiviral drug approved candidate Candidates Compound compounds COVID-19 COVID-19 pandemic COVID-19 virus database diterpene drug effort eight Ent-kaurane enzyme Health Infection inhibitor inhibitors main protease inhibitors molecular docking MPro Nature nucleus overcome pharmacophore positive problems protease protease inhibitors proteinase provide reported SARS-CoV-2 SARS-CoV-2 main protease suggested terpenoids triggered Virtual screening virus infection [DOI] 10.1016/j.virol.2022.03.003 PMC 바로가기 [Article Type] Article
Automated virtual reality therapy to treat agoraphobic avoidance and distress in patients with psychosis (gameChange): a multicentre, parallel-group, single-blind, randomised, controlled trial in England with mediation and moderation analysesRandomized Controlled Trial Published on 2022-05-012022-10-05 Journal: The lancet. Psychiatry [Category] Fulltext, MERS, 임상, [키워드] 1:1 95% CI added adjusted affective age Algorithm Analysis Anxiety assigned automated avoidance block Clinical diagnosis cognitive Controlled trial COVID-19 pandemic Diagnosis disorder distress Effect effective Efficacy eight eligibility England enrolled evaluate event greater help indicated Innovation intention-to-treat population invention ISRCTN Local mean difference Mediation analysis men multicentre National Health Service nine no significant difference Occurrence Older outcomes Oxford parallel-group participant Patient patients performed primary endpoint Primary outcome Protective behaviours provided psychological therapy randomisation randomised Randomly recruitment reducing reduction reductions in Registered scale Schizophrenia Serious Adverse Event Seven severity single-blind stratified study group Symptoms the mean therapy thought Transport treat Treatment Trial usual care usual care alone were assessed white women [DOI] 10.1016/S2215-0366(22)00060-8 PMC 바로가기 [Article Type] Randomized Controlled Trial
Spontaneous Retroperitoneal Hematoma Treated with Percutaneous Transarterial Embolization in COVID-19 Era: Diagnostic Findings and Procedural OutcomeCOVID-19 시대에 경피적 경동맥 색전술로 치료한 자발성 복막후혈종: 진단 소견 및 시술 결과Article Published on 2022-05-012022-09-11 Journal: Tomography [Category] COVID19(2023년), SARS, 치료기술, [키워드] affected age angiography aPTT benefit bleeding blind both groups clinical complications conservative treatment COVID-19 COVID-19 group COVID-19 infection COVID-19 patient CTA demographic data diagnostic digital subtraction effective eight embolization enrolled evaluate evaluated failure feature finding Gender hematoma hemoglobin hemoglobin value hemoglobin values Hospitalized hospitalized patient hospitalized patients in both groups INR interventional management material non-COVID-19 group non-COVID-19 patient Non-COVID-19 patients Occurrence outcome Patient Percutaneous Pneumonia radiology reported Retroperitoneal retroperitoneal space retroperitoneal space. Safe SARS-CoV-2 SARS-COV-2 infection Seven Spontaneous statistical significance statistically significant difference study population supportive therapy survival therapy Treatment two group two groups Volume was obtained was performed with COVID-19 [DOI] 10.3390/tomography8030101 PMC 바로가기 [Article Type] Article