Mechanisms of COVID-19-induced cardiovascular disease, is sepsis or exosome the missing link?Review Published on 2020-10-222023-06-16 Journal: Journal of cellular physiology [Category] MERS, SARS, [키워드] cardiovascular disease COVID-19 Exosomes SARS-CoV-2 Sepsis [DOI] 10.1002/jcp.30109 PMC 바로가기 [Article Type] Review
Extracellular Vesicles in the Pathogenesis of Viral Infections in HumansReview Published on 2020-10-212022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] alteration amplification antiviral immune responses Cell Cellular responses clinically complex coronavirus Enzymes EVs Exosomes extracellular vesicle extracellular vesicles (EVs) facilitate Herpes virus HIV Human Human immunodeficiency virus immune response in viral inhibiting Intercellular communication mechanisms membrane vesicle modulate modulation MOST neurotropic nucleic acids Pathogenesis pathogenicity pathology Proteins retrovirus signaling molecules Therapeutics viral infection viral pathogenicity viral spread viruses Zika Zika virus ZIKV [DOI] 10.3390/v12101200 PMC 바로가기 [Article Type] Review
Mesenchymal Stem Cells and Their Extracellular Vesicles: A Potential Game Changer for the COVID-19 CrisisCell and Developmental Biology Published on 2020-09-302022-10-31 Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19, [키워드] “cytokine storm” acute respiratory distress ARDS Corona virus COVID-19 COVID-19 patient COVID-19 patients crisis Cytokine storm death dependent on disease Effects ENhance Exosomes Extracellular vesicles game global public health help immune response immune system immunomodulation immunomodulatory effect immunomodulatory property IMPROVE induce infected patients Inflammatory response intervene kill lack mechanism Mesenchymal stem cells MSC MSCs Multi-organ damage organ outbreak outcome Patient Potential preventive measure PROTECT provide regulate responsible resulting SARS-CoV-2 severe cases severity of COVID-19 STEM stem cell syndrome the disease therapeutic tissue-repair Treatment turn virus [DOI] 10.3389/fcell.2020.587866 PMC 바로가기 [Article Type] Cell and Developmental Biology
Endothelial Cell Contributions to COVID-19Review Published on 2020-09-252022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] Affect canonical caused cellular coronavirus coronavirus 2 Coronavirus disease 2019 Coronaviruses COVID-19 dysfunction endothelial Endothelial cell endothelial cells endothelial function event Evidence Exosome Exosomes explain histological increased mortality infect inflammatory reaction knowledge molecular molecular feature Novel coronavirus pathology pathway recent related viruses remained replicate respiratory SARS-CoV-2 therapeutic transdifferentiation understanding Vascular virus [DOI] 10.3390/pathogens9100785 PMC 바로가기 [Article Type] Review
Inhibiting Extracellular Vesicle Trafficking as Antiviral Approach to Corona Virus Disease 2019 InfectionPharmacology Published on 2020-09-042022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] Corona Drug repurposing Exosomes Extracellular vesicles Severe Acute Respiratory Syndrome-Associated Coronavirus-2 infection viruses [DOI] 10.3389/fphar.2020.580505 PMC 바로가기 [Article Type] Pharmacology
State of the Art Review of Cell Therapy in the Treatment of Lung Disease, and the Potential for Aerosol DeliveryReview Published on 2020-09-032022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] acute respiratory distress administration aerosol Anti-inflammatory ARDS ATMP cause Cell chronic obstructive clinically conditioned media COPD COVID-19 death delivery disease Diseases effective exhibited Exosomes incurable longitudinal study lung mesenchymal stem cell MSC nebulizer novel patients pharmacological Potential pulmonary disease pulmonary diseases Quality of life reducing mortality respiratory Respiratory disease review Secretome selected state syndrome therapeutic potential therapy treat [DOI] 10.3390/ijms21176435 PMC 바로가기 [Article Type] Review
Rationale for the Use of Radiation-Activated Mesenchymal Stromal/Stem Cells in Acute Respiratory Distress Syndrome급성 호흡곤란 증후군에서 방사선 활성화 중간엽 간질/줄기세포 사용의 근거Review Published on 2020-09-022022-09-11 Journal: Cells [Category] SARS, 비임상, [키워드] activated acute respiratory-distress syndrome alleviate Analysis Annexin annexin A1 ARDS breath caused Cell Cell therapy cells characteristic Combination conditions COVID-19 dramatic increase Exosome Exosomes experimental radiotherapy greater Hypothesis hypothetical hypoxia IMPROVE Inflammation intensive care intensive care unit life-threatening load mesenchymal cells Mesenchymal stem cells Metastasis mice microvesicle Microvesicles MSC MSCs Patient Pneumonia Protein Proteins proteomic Proteomic analysis Radiation radiobiology Radiotherapy rationale reduce released respiratory respiratory capacity SARS-CoV-2 secreted shown significant difference significantly stimulated Symptom the cells therapeutic strategy therapy transplantation Tumor [DOI] 10.3390/cells9092015 PMC 바로가기 [Article Type] Review
Nano-Vesicle (Mis)Communication in Senescence-Related PathologiesReview Published on 2020-08-262022-10-31 Journal: Cells [Category] Coronavirus, MERS, [키워드] aging apoptotic bodies biological fluid cells cellular senescence changes COVID-19 COVID-19 infections Critical death Diseases Exosome exosome biogenesis Exosomes extracellular vesicle Extracellular vesicles heterogeneous group homeostasis information involved Microvesicles miRNA multivesicular body nucleic acids organ physiological plasma Potential biomarker Probability Protein Saliva senescent Signaling Structure susceptibility Transport Urine Vesicle [DOI] 10.3390/cells9091974 PMC 바로가기 [Article Type] Review
Coronavirus disease 2019: A tissue engineering and regenerative medicine perspectiveConcise Review Published on 2020-08-212022-10-28 Journal: Stem cells translational medicine [Category] COVID-19, MERS, [키워드] acute respiratory distress acute respiratory distress syndrome antiviral agent Antiviral agents ARDS biomaterial caused cell processing clinical trial clinical trials conducted Coronavirus infections COVID‐19 current death derivative described disease Disease progression driving Effect effective Efficacy evaluate Exosomes Impact infective Inflammation Last majority medical need mesenchymal stem cell MSC MSC therapy MSCs novel coronavirus disease pandemic Perspective platform progression regenerative required Research Safe stem cell syndrome the disease Therapeutic benefit Therapies therapy tissue Treatment Vaccine [DOI] 10.1002/sctm.20-0197 PMC 바로가기 [Article Type] Concise Review
Exosomes in Angiogenesis and Anti-angiogenic Therapy in CancersReview Published on 2020-08-142023-08-30 Journal: International Journal of Molecular Sciences [Category] E형 간염, [키워드] Angiogenesis anti-angiogenic therapy Exosomes Extracellular vesicles [DOI] 10.3390/ijms21165840 PMC 바로가기 [Article Type] Review