SARS-CoV-2 Infection: A Role for S1P/S1P Receptor Signaling in the Nervous System?
Hypothesis
[키워드] ACE2
acute respiratory syndrome
airway
angiotensin-converting enzyme 2
approved
bind
Cell
clinical manifestations
Complication
contributing to
coronavirus disease
Coronavirus-2
COVID-19
fingolimod
FTY720
function
help
host–virus interaction
implicated
in some
individuals
induce
infect
Inflammation
limit
Loss of Smell
lung
majority
mechanisms
Mild
modulation
morbidity and mortality
multiple sclerosis
nasal
nervous
nervous system
Neurological symptoms
Olfactory epithelium
organs
overcome
Pathogenesis
patients
pleiotropic
receptor
receptors
regulate
replicate
responsible
role
SARS-CoV-2
severe pulmonary disease
Signaling
sphingosine 1-phosphate
sphingosine 1-phosphate receptors
Spread
survival
tested
therapeutic strategy
tissues
Treatment
viral infection
virus
virus propagation
[DOI] 10.3390/ijms21186773 PMC 바로가기 [Article Type] Hypothesis
[DOI] 10.3390/ijms21186773 PMC 바로가기 [Article Type] Hypothesis