Potential SARS-CoV-2 Preimmune IgM EpitopesImmunology Published on 2020-04-302022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, SARS, [키워드] B cell precursors effort epitope Frame HCoV 229E IgM linear mimotope OC43 peptide Potential Protein representing SARS-CoV SARS-CoV-2 SARS-CoV-2 vaccine the spike protein while [DOI] 10.3389/fimmu.2020.00932 PMC 바로가기 [Article Type] Immunology
Coronaviruses and SARS-COV-2Article Published on 2020-04-212022-10-29 Journal: Turkish Journal of Medical Sciences [Category] COVID-19, SARS, [키워드] acute respiratory disease acute respiratory syndrome aetiology Animal coronaviruses China common cold coronavirus coronavirus disease COVID-19 CoVs death deaths disease HCoV 229E history of coronaviruses HKU1 human coronaviruses human infection humans individuals MERS-CoV Middle East Mild National NL63 OC43 outbreak patients with pneumonia Pneumonia reported respiratory syndrome coronavirus rodents SARS-CoV SARS-CoV-2 severe respiratory illness spectrum of disease study group Symptom Turkey virus WHO widespread wild animals zoonotic [DOI] 10.3906/sag-2004-127 PMC 바로가기 [Article Type] Article
Initial success in the identification and management of the coronavirus disease 2019 (COVID-19) indicates human-to-human transmission in Wuhan, ChinaReview Published on 2020-04-062022-10-29 Journal: International Journal of Biological Sciences [Category] COVID-19, MERS, SARS, [키워드] 2019-nCoV 229E caused Characteristics Clinical symptoms coronavirus coronavirus disease CoV COVID-19 death diagnostic methods disease Epidemiology Health HKU1 human-to-human transmission indicate Infection management MERS-CoV NL63 OC43 occurred outbreak Outbreaks pandemic prevention respiratory risk SARS-CoV SARS-CoV-2 threat Treatment Virological Wuhan, China [DOI] 10.7150/ijbs.45018 PMC 바로가기 [Article Type] Review
Severity of coronavirus respiratory tract infections in adults admitted to acute care in Toronto, OntarioArticle Published on 2020-03-292022-11-01 Journal: Journal of Clinical Virology [Category] Coronavirus, MERS, [키워드] Admission all-cause mortality average Care Cohort coronavirus CoV CoVs cross-sectional death Disease burden disease severity Epidemiology evaluated female gender gastrointestinal tract Gender Health highlight Human ICU ICU admission identify Infection Influenza virus intensive care likelihood majority morbidity and mortality Mortality multivariate model nosocomial objective OC43 Patient poor prognosis positive Prevalence respiratory tract infection respiratory virus respiratory viruses Result Risk factors RNA severe disease smoking Surveillance Symptoms Toronto variable was performed World Health Organization [DOI] 10.1016/j.jcv.2020.104338 PMC 바로가기 [Article Type] Article
Using the spike protein feature to predict infection risk and monitor the evolutionary dynamic of coronavirusResearch Article Published on 2020-03-252022-10-29 Journal: Infectious Diseases of Poverty [Category] COVID-19, MERS, SARS, [키워드] 229E Algorithm Amino acid center China circulating Cluster collected coronavirus correlation coefficient cross Cross-species infection enzyme II evaluate Genome Genomics HKU1 Human human coronavirus infect infection risk information machine learning MCC MERS-CoV MONITOR multidimensional Mutation NL63 novel OC43 performed positive predict Predictive public health random receptor Result SARS-CoV SARS-CoV-2 severe respiratory syndrome Spike protein Spike protein sequence Surveillance the spike protein virus was used were used [DOI] 10.1186/s40249-020-00649-8 PMC 바로가기 [Article Type] Research Article
Coronavirus infections: Epidemiological, clinical and immunological features and hypothesesEditorial Published on 2020-03-022022-10-31 Journal: Cell Stress [Category] COVID-19, [키워드] acute respiratory syndrome caused clinical presentation Cluster contagious coronavirus CoV COVID-19 CoVs Endemic Epidemic Epidemics Epidemiology Evolution feature fraction globe HCoV 229E HKU1 human CoV hypothese Immunity immunological immunology Infection infections Infectious disease knowledge measure MERS-CoV Mortality NL63 OC43 occur Outbreaks pandemic Patient public health reduce respiratory syndrome coronavirus risk RNA viruses SARS-CoV SARS-CoV-2 SARS-CoV-2 epidemic severe disease Severe infection short-lived Spread subject understanding upper respiratory tract virus [DOI] 10.15698/cst2020.04.216 PMC 바로가기 [Article Type] Editorial
Transmission and evolutionary dynamics of human coronavirus OC43 strains in coastal Kenya investigated by partial spike sequence analysis, 2015–16Research Article Published on 2020-01-022022-10-28 Journal: Virus Evolution [Category] COVID-19, [키워드] acute respiratory illness Analysis ARI Characteristics China circulating clade Cluster Clusters coronavirus effective Epidemiology Evolution evolutionary dynamics Genetic genetic diversity Genotype geographical area globe HCoV-OC43 Health Human human coronavirus OC43 investigated Kenya nine nucleotide OC43 occurred outbreak Outpatient Patient Phylogenetic relationship positive required respiratory pathogen sequence Sequence analysis sequenced similarity spike spike gene Spread strain Strains Surveillance tested threshold transmission pathway USA virus yielding [DOI] 10.1093/ve/veaa031 PMC 바로가기 [Article Type] Research Article
Natural Bis-Benzylisoquinoline Alkaloids-Tetrandrine, Fangchinoline, and Cepharanthine, Inhibit Human Coronavirus OC43 Infection of MRC-5 Human Lung CellsArticle Published on 2019-11-042022-10-28 Journal: Biomolecules [Category] Coronavirus, [키워드] activities Anti-inflammatory anticancer antiviral activity Antiviral effect bis-benzylisoquinoline alkaloids Cepharanthine Compound coronavirus early stage expression fangchinoline HCoV-OC43 host response Human human coronavirus human coronavirus strain OC43 human lung cells include Infection inhibited mechanism MRC-5 human lung cell N protein natural natural antiviral OC43 pharmacological Replication significantly Stephania suppressed TET tetrandrine these compound Treatment virus infection virus-induced cell death was reduced [DOI] 10.3390/biom9110696 PMC 바로가기 [Article Type] Article
Viral nucleic acid analysis with PCR in lacrimal tissue and nasal swab samples of primary acquired nasolacrimal duct obstruction casesOriginal Research Article Published on 2019-10-212022-10-31 Journal: European Journal of Ophthalmology [Category] Coronavirus, [키워드] Adenovirus age Analysis Characteristics coronavirus coronavirus 229E diagnosed evaluate Factor HKU1 men mucosal nasal nasal swab NL63 nucleic acid nucleic acid extraction OC43 Pathogenesis Patient patients PCR polymerase chain polymerase chain reaction positive primary acquired nasolacrimal duct obstruction Qualitative respiratory syncytial virus statistically significant Swab tissue viral genome viral infection virus was performed women [DOI] 10.1177/1120672119882331 PMC 바로가기 [Article Type] Original Research Article
Comparative Serological Study for the Prevalence of Anti-MERS Coronavirus Antibodies in High- and Low-Risk Groups in QatarResearch Article Published on 2019-02-182022-10-29 Journal: Journal of Immunology Research [Category] Coronavirus, [키워드] 229E Active surveillance antibody Asymptomatic baseline circulating close contact collected Comparative Contact coronavirus cross-reactivity determine epidemiological evaluate exhibited false-positive result FIVE General population group healthy blood donor HKU1 human coronavirus IgG IgM individual initial screening MERS-CoV MERS-CoV infection Middle East Mild neutralization NL63 OC43 PCR-confirmed patient positive Prevalence Randomly reactive reactivity reported respiratory syndrome coronavirus Sample screened selected Serological assay serological assays [DOI] 10.1155/2019/1386740 PMC 바로가기 [Article Type] Research Article