Assessing a chip based rapid RTPCR test for SARS CoV-2 detection (TrueNat assay): A diagnostic accuracy studySARS COV-2 탐지 (Truenat Assay)에 대한 칩 기반 신속한 RTPCR 테스트 평가 : 진단 정확도 연구Research Article Published on 2021-10-132022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 진단, 치료기술, [키워드] Accuracy Admission Assessing biosafety can be used Chain Reaction ChIP collected COVID-19 testing Diagnosis diagnosis of COVID-19 diagnostic Diagnostic accuracy diagnostic test diagnostics equipment evaluated gold gold standard hospitals invasive Laboratory molecular molecular diagnostics Patient PCR test polymerase chain reaction positive real time real time PCR real time Polymerase Chain Reaction required resource SARS CoV SARS CoV-2 sensitivity specificity study period time [DOI] 10.1371/journal.pone.0257834 PMC 바로가기 [Article Type] Research Article
Transmission of community- and hospital-acquired SARS-CoV-2 in hospital settings in the UK: A cohort studyObservational Study Published on 2021-10-122022-10-04 Journal: PLoS Medicine [Category] MERS, SARS, 임상, [키워드] absence Admission Affect age analysed association assumption Clinical management cohort study collected data Community complications contribute coronavirus 2 COVID-19 COVID-19 patient CrI Critical discharge driver Evidence example exposure to females first positive HCW HCWs healthcare worker high risk hospital hospitalised Hospitalised patients hospitals identify identifying Improved incidence Incubation period individual infected patient infected with SARS-CoV-2 Infection Infection prevention infection risk infections Isolation less limit limitation linear Logistic measure Measures mitigate nosocomial Nurses Observational cohort study occurred onward transmission pathway Patient patients PCR PCR test per day Personal protective equipment positive positive SARS-CoV-2 PCR Prevent PROTECT quantified reduced reported researcher respiratory risk risk factor risk of transmission SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 infection sensitivity analysis serological sick Spread statistical study period Support susceptible susceptible individual susceptible patient susceptible patients symptom onset tested Transmission transmission pathway transmission pathways United Kingdom [DOI] 10.1371/journal.pmed.1003816 PMC 바로가기 [Article Type] Observational Study
A prospective, randomized, single-blinded, crossover trial to investigate the effect of a wearable device in addition to a daily symptom diary for the Remote Early Detection of SARS-CoV-2 infections (COVID-RED): a structured summary of a study protocol for a randomized controlled trialSARS-COV-2 감염 (COVID-RED)의 원격 조기 발견을위한 일일 증상 일기 외에 웨어러블 장치의 효과를 조사하기위한 전향 적, 무작위, 단일 맹장, 크로스 오버 시험 : 연구의 구조적 요약.무작위 제어 시험을위한 프로토콜Update Published on 2021-10-112022-09-01 Journal: Trials [Category] MERS, SARS, 임상, 진단, 치료기술, 치료제, [키워드] 1:1 addition adhere Algorithm Algorithms all subject all subjects among others analysed antibody Antibody testing antibody tests Antigen antigen tests approach asked assigned Asymptomatic asymptomatic individual asymptomatic infection average baseline blinded Blinding can not capillary blood Chain Reaction changes in Characteristics cholinergic urticaria Cohort collected Complete conditions conducted consent form contribute control condition COVID-19 COVID-19 infection COVID-19 vaccination current Daily defined demographics described detect detection determine develop deviation diary dissemination Early detection element eligibility criteria eligible End enrolled enrolment evaluate exclusion exploratory feedback Follow-up followed by gold gold standard Health health resource heart rate incidence rates Inclusion inclusion criteria individual individuals infected individual infected individuals infected with SARS-CoV-2 Infection information Informed consent informed consent form initial involved Laboratory laboratory-confirmed SARS-CoV-2 infection machine learning management maximum media medical history Mobile application must nasal swab National natural infection Negative predictive value Netherland Netherlands notification NPV number objective occur outcome pacemaker parameter participant PCR PCR test PCR tests physiological physiological parameters polymerase chain polymerase chain reaction populations portal positive Positive predictive value PPV pre-symptomatic Predictive value primary analysis profession proportion Prospective protocol provided public health Pulse rate questionnaire randomization randomization sequence Randomized Randomized controlled trial Randomly receive recommendation recruited recruitment reduce remote reported resident resource responsible resulting risk RIVM Sample size SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 test SARS-CoV-2 virus sensitivity sequence sequence 1 Sequence 2 sequences serology serology test serology tests significantly skin temperature Smartphone social media specificity staff stratified stratified block randomization study participation Study protocol subject suffering supplementary material Symptom Symptom diary Symptoms target temperature test result tested the SARS-CoV-2 thought Transmission transmissions Trial Trial registration undergo urticaria used to evaluate vaccinated against COVID-19 vaccination Vaccine Variability wearable device website Well-being [DOI] 10.1186/s13063-021-05643-5 PMC 바로가기 [Article Type] Update
Impact of the third wave of the COVID-19 pandemic and interventions to contain the virus on society and patients with kidney disease in CambodiaReview Published on 2021-10-092022-10-28 Journal: Renal Replacement Therapy [Category] COVID-19, [키워드] affected Against appear Cambodia Care Chronic kidney disease Cluster conducted country COVID-19 COVID-19 pandemic COVID-19 vaccination dialysis End-stage renal disease food insecurity Government Health workers in nephrology healthcare worker Hemodialysis hemodialysis patients high risk Impact IMPROVE increasingly Intervention Kidney disease lockdown measure Mental outbreak Outbreaks pandemic Patient PCR test PHEIC physical Quality of life receiving reported risk of transmission SARS-CoV-2 Socioeconomic hardship Spread Stress survival Travel virus WHO widespread [DOI] 10.1186/s41100-021-00372-6 PMC 바로가기 [Article Type] Review
A Prospective Cohort Study in Nonhospitalized Household Contacts With Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Symptom Profiles and Symptom Change Over Time중증 급성 호흡기 증후군 코로나바이러스 2 감염이 있는 입원하지 않은 가구 접촉에 대한 전향적 코호트 연구: 시간 경과에 따른 증상 프로필 및 증상 변화Article Published on 2021-10-052022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age Asymptomatic asymptomatic infection asymptomatic infections Chain Reaction change characterized collected Community community. Contact Contact tracing contribute coronavirus coronavirus 2 COVID-19 COVID-19 symptoms described detectable disease enrolled Fever first positive household household contact household contacts Improved individual infection control laboratory-confirmed SARS-CoV-2 infection less median age Mild mild or asymptomatic infections mild symptoms nasopharyngeal specimen neurologic over PCR test polymerase chain polymerase chain reaction profile progression Prospective Public health interventions Recognition reported reported symptom resolved respiratory respiratory symptom respiratory symptoms rRT-PCR rRT-PCR test SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus Symptom Symptoms tested time upper respiratory Utah Viral transmission [DOI] 10.1093/cid/ciaa1072 PMC 바로가기 [Article Type] Article
Sewage as a Possible Transmission Vehicle During a Coronavirus Disease 2019 Outbreak in a Densely Populated Community: Guangzhou, China, April 2020인구 밀도가 높은 지역 사회에서 코로나 바이러스 질병 2019 발생 중 가능한 전송 수단으로서의 하수: 중국 광저우, 2020년 4월Article Published on 2021-10-052022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술, [키워드] apartment collected conducted COVID-19 COVID-19 outbreak demonstrated disease disease outbreak Genome sequencing Guangzhou Guangzhou, China hand handling highlighting homologous identify Incubation period Infectious disease infectious disease transmission investigated janitor management mode Outbreaks PCR test pipes positive RT-PCR resident retrospective cohort study Risk factors RT-PCR RT-PCR testing SARS-CoV-2 sewage sewage management. Spread squat toilet Symptoms Transmission transmission of SARS-CoV-2 vehicle working [DOI] 10.1093/cid/ciaa1494 PMC 바로가기 [Article Type] Article
COVID-19 Infection Alters the Microbiome: Elite Athletes and Sedentary Patients Have Similar Bacterial FloraClinical Trial Published on 2021-10-042022-10-04 Journal: Genes [Category] MERS, SARS, 임상, [키워드] all subject Alter Analysis athlete Bacterial Bacteroidete Bacteroidetes collected competing COVID-19 COVID-19 infection COVID-19 PCR test diagnosed Diagnosis Efficiency eight elevated Elite exercise female females FIVE Flora Hypothesis immune system individuals Infection Inflammation male Microbiome Mild Mild symptom National Negative PCR no difference PCR test positive pro-inflammatory cytokines quarantine regular exercise reported Severe COVID-19 Infection Signaling Significant statistical analysis subject subjects suggested suppress tested toll-like receptor 4 were used [DOI] 10.3390/genes12101577 PMC 바로가기 [Article Type] Clinical Trial
Symptoms, SARS-CoV-2 Antibodies, and Neutralization Capacity in a Cross Sectional-Population of German ChildrenPediatrics Published on 2021-10-042022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] acute phase affected age and sex antibody Antibody Response Antibody test Capacity children COVID-19 COVID-19 symptom cross-sectional design detectable Elecsys eligible First wave Health identify immune immune reaction Infection Loss of Smell N-protein neutralization activity neutralization capacity Neutralizing Neutralizing activity pandemic parent PCR positive PCR test performed positive primary care proportion Randomly recruited Region response Roche S-protein SARS-CoV-2 SARS-COV-2 infection Seroconversion vaccination Viral proteins was determined were recorded [DOI] 10.3389/fped.2021.678937 PMC 바로가기 [Article Type] Pediatrics
Real-world evaluation of COVID-19 lateral flow device (LFD) mass-testing in healthcare workers at a London hospital; a prospective cohort analysis런던 병원의 의료 종사자를 대상으로 한 COVID-19 측면 흐름 장치(LFD) 대량 테스트의 실제 평가. 전향적 코호트 분석Article Published on 2021-10-012022-09-11 Journal: The Journal of Infection [Category] SARS, 치료기술, [키워드] 95% CI Analysis Antigen Asymptomatic Atypical atypical symptom COVID-19 COVID-19 testing diagnostics facilitate False positive False positives healthcare healthcare worker hospital Hospital staff individual Isolation Lateral Lateral flow device lateral flow immunoassay Lateral flow tests LFD London Negative PCR NHS outcome measure participated PCR PCR positive PCR test PCR testing PHE point-of-care portal positive positive PCR result Positive predictive value PPV Predictive value prevalence of COVID-19 profile profiles prospective cohort reported SARS CoV-2 SARS-CoV-2 secondary secondary care secondary outcome measures staff submitted subsequent Symptom symptomatic Symptoms took place true positive true positives Trust twice weekly was measured was obtained yielding [DOI] 10.1016/j.jinf.2021.07.038 PMC 바로가기 [Article Type] Article
Outcome of COVID-19 infection in 50 multiple myeloma patients treated with novel drugs: single-center experience다발성 골수종 환자 50명 코로나19 감염 결과 신약 치료: 단일 센터 경험Article Published on 2021-10-012022-09-12 Journal: Annals of Hematology [Category] MERS, SARS, 진단, [키워드] age Cohort Course COVID-19 COVID-19 diagnosis COVID-19 disease COVID-19 hospitalization COVID-19 infection death deaths died disease drugs evaluate Factor female Gender Hospitalization ICU incidence intensive care ISS male median median age moderate morbidity and mortality Mortality Multiple Multiple myeloma novel Novel drugs. outcome Outpatient parameter Patient patients treated PCR test performance status Pneumonia presence of comorbidity Retrospective analysis risk factor single-center statistically significant treated Treatment [DOI] 10.1007/s00277-021-04594-w PMC 바로가기 [Article Type] Article